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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Splenic Neoplasms
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Accession:DOID:9005343 term browser browse the term
Definition:Tumors or cancer of the SPLEEN.
Synonyms:exact_synonym: spleen neoplasm;   spleen neoplasms;   splenic neoplasm
 primary_id: MESH:D013160


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Splenic Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26558449 NCBI chrNW_004955476:11,508,446...11,510,333
Ensembl chrNW_004955476:11,508,126...11,510,333
JBrowse link
spleen cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ramp2 receptor activity modifying protein 2 ameliorates ISO RGD PMID:31754214 RGD:152985691 NCBI chrNW_004955451:16,584,742...16,586,093 JBrowse link
splenic marginal zone lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd79b CD79b molecule ISO protein:decreased expression:blood, B cell (human) RGD PMID:10329919 RGD:11531139 NCBI chrNW_004955478:7,909,353...7,912,814
Ensembl chrNW_004955478:7,909,153...7,913,166
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16047
    disease of cellular proliferation 6669
      Neoplasms by Site 6183
        Splenic Neoplasms 3
          Littoral Cell Angioma of the Spleen 0
          spleen cancer + 2
Path 2
Term Annotations click to browse term
  disease 16047
    disease of anatomical entity 13770
      Immune & Inflammatory Diseases 4589
        immune system disease 3995
          lymphatic system disease 1467
            splenic disease 137
              Splenic Neoplasms 3
                Littoral Cell Angioma of the Spleen 0
                spleen cancer + 2
paths to the root