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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Splenic Neoplasms
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Accession:DOID:9005343 term browser browse the term
Definition:Tumors or cancer of the SPLEEN.
Synonyms:exact_synonym: spleen neoplasm;   spleen neoplasms;   splenic neoplasm
 primary_id: MESH:D013160


show annotations for term's descendants           Sort by:
Splenic Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HRAS HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26558449 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078 		JBrowse link
spleen cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAMP2 receptor activity modifying protein 2 ameliorates ISO RGD PMID:31754214 RGD:152985691 NCBI chr17:14,554,888...14,557,175
Ensembl chr17:14,779,666...14,781,481 		JBrowse link
splenic marginal zone lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD79B CD79b molecule ISO protein:decreased expression:blood, B cell (human) RGD PMID:10329919 RGD:11531139 NCBI chr17:58,022,375...58,026,359
Ensembl chr17:63,116,722...63,120,335 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17918
    disease of cellular proliferation 7215
      Neoplasms by Site 6695
        Splenic Neoplasms 3
          Littoral Cell Angioma of the Spleen 0
          spleen cancer + 2
Path 2
Term Annotations click to browse term
  disease 17918
    disease of anatomical entity 15172
      Immune & Inflammatory Diseases 4990
        immune system disease 4345
          lymphatic system disease 1575
            splenic disease 149
              Splenic Neoplasms 3
                Littoral Cell Angioma of the Spleen 0
                spleen cancer + 2
paths to the root