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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Stable Angina
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Accession:DOID:9005269 term browser browse the term
Definition:Persistent and reproducible chest discomfort usually precipitated by a physical exertion that dissipates upon cessation of such an activity. The symptoms are manifestations of MYOCARDIAL ISCHEMIA.
Synonyms:exact_synonym: Chronic Stable Angina;   Chronic Stable Anginas;   Stable Angina Pectori;   Stable Angina Pectoris;   Stable Anginas
 primary_id: MESH:D060050


show annotations for term's descendants           Sort by:
Stable Angina term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F7 coagulation factor VII ISO protein:increased activity:plasma (human) RGD PMID:17357481 RGD:11049525 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G MIR126 microRNA mir-126 ISO RNA:decreased expression:plasma RGD PMID:27900989 RGD:401850572
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G RBP4 retinol binding protein 4 ISO protein:increased expression:blood serum (human) RGD PMID:25142320 RGD:329845867 NCBI chr14:105,037,360...105,044,552
Ensembl chr14:105,037,464...105,044,765 		JBrowse link
G TLR4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17415
    disease of anatomical entity 14875
      cardiovascular system disease 4329
        heart disease 3043
          Myocardial Ischemia 872
            Angina Pectoris 41
              Stable Angina 6
Path 2
Term Annotations click to browse term
  disease 17415
    disease of anatomical entity 14875
      cardiovascular system disease 4329
        vascular disease 3053
          ischemia 1401
            Myocardial Ischemia 872
              Angina Pectoris 41
                Stable Angina 6
paths to the root