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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Mammary Neoplasms, Experimental
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Accession:DOID:9005233 term browser browse the term
Definition:Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.
Synonyms:exact_synonym: Experimental Mammary Neoplasm
 primary_id: MESH:D008325;   RDO:0006058
For additional species annotation, visit the Alliance of Genome Resources.


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Mammary Neoplasms, Experimental term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO RGD PMID:19654309 RGD:2315553 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO CTD Direct Evidence: therapeutic CTD PMID:22767648 NCBI chr 4:80,379,108...80,446,641
Ensembl chr 4:91,101,321...91,170,157
JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:176,920,811...176,991,495
Ensembl chr 4:189,145,403...189,198,646
JBrowse link
G ACTG1 actin gamma 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr17:75,965,911...75,968,822
Ensembl chr17:81,668,221...81,671,087
JBrowse link
G ACTN4 actinin alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr19:35,742,758...35,825,321
Ensembl chr19:44,313,569...44,395,508
JBrowse link
G ADCY5 adenylate cyclase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:120,380,094...120,545,725
Ensembl chr 3:127,283,921...127,446,508
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing treatment
disease_progression
ISO RGD PMID:19447866, PMID:22246620 RGD:8694414, RGD:8694468 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G AFP alpha fetoprotein ISO CTD Direct Evidence: therapeutic CTD PMID:16322315 NCBI chr 4:50,739,197...50,758,459
Ensembl chr 4:56,571,519...56,590,391
JBrowse link
G AGT angiotensinogen treatment ISO RGD PMID:20837666 RGD:5129167 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:18421211 RGD:2292665 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8389152 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:17210696 RGD:2315600 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO RGD PMID:17210696 RGD:2315600 NCBI chr19:37,275,799...37,331,971
Ensembl chr19:45,791,800...45,840,271
JBrowse link
G ALCAM activated leukocyte cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 3:102,468,354...102,677,932
Ensembl chr 3:109,407,992...109,616,518
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein ISO mRNA:increased expression:mammary gland tumor (rat) RGD PMID:18959458 RGD:2313895 NCBI chr13:12,012,399...12,041,557
Ensembl chr13:30,425,510...30,476,607
JBrowse link
G ANTXR1 ANTXR cell adhesion molecule 1 disease_progression ISO RGD PMID:22085271 RGD:9684855 NCBI chr2A:69,054,253...69,290,554
Ensembl chr2A:70,175,982...70,412,454
JBrowse link
G ANXA1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12376462, PMID:16316942 RGD:2306898 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779
JBrowse link
G ANXA4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr2A:69,686,651...69,869,340
Ensembl chr2A:70,902,260...70,986,917
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 ISO RGD PMID:14973070 RGD:2325748 NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939
JBrowse link
G APOE apolipoprotein E ISO RGD PMID:22469977 RGD:7771597 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 7:31,524,933...31,538,602 JBrowse link
G AR androgen receptor ISO RGD PMID:12150826 RGD:6482679 NCBI chr  X:56,722,828...56,909,004
Ensembl chr  X:66,791,081...66,969,357
JBrowse link
G AREG amphiregulin ISO protein:increased expression:mammary gland
mRNA:increased expression:mammary gland
RGD PMID:10225449, PMID:18421211 RGD:2292663, RGD:2292665 NCBI chr 4:49,737,191...49,747,013 JBrowse link
G ATP5IF1 ATP synthase inhibitory factor subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462, PMID:16316942 NCBI chr 1:27,495,250...27,497,255
Ensembl chr 1:28,532,091...28,542,607
JBrowse link
G AURKA aurora kinase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12124350 NCBI chr20:52,707,757...52,730,579
Ensembl chr20:53,994,881...54,017,339
JBrowse link
G BAD BCL2 associated agonist of cell death severity
treatment
ISO RGD PMID:20732338, PMID:23404339 RGD:10053670, RGD:10053708 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO RGD PMID:19222350 RGD:2315700 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BARD1 BRCA1 associated RING domain 1 ISO RGD PMID:18443292 RGD:2293149 NCBI chr2B:101,984,287...102,068,523
Ensembl chr2B:220,456,972...220,541,145
JBrowse link
G BASP1 brain abundant membrane attached signal protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 5:17,521,054...17,580,999 JBrowse link
G BAX BCL2 associated X, apoptosis regulator severity
treatment
ISO RGD PMID:20732338, PMID:23404339 RGD:10053670, RGD:10053708 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:22668016, PMID:23404339 RGD:10053670, RGD:10054128 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BCL2L1 BCL2 like 1 treatment ISO RGD PMID:23404339 RGD:10053670 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585
JBrowse link
G BRCA1 BRCA1 DNA repair associated susceptibility ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:12203372, PMID:17505536, PMID:18443292, PMID:22767648 RGD:1599502, RGD:2293149, RGD:2293155 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G BST2 bone marrow stromal cell antigen 2 disease_progression ISO RGD PMID:23806386 RGD:14398495 NCBI chr19:16,890,257...16,892,989
Ensembl chr19:17,863,991...17,866,728
JBrowse link
G CA9 carbonic anhydrase 9 ISO RGD PMID:17280655 RGD:2293194 NCBI chr 9:35,525,877...35,533,159
Ensembl chr 9:36,328,303...36,335,340
JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase disease_progression ISO protein:increased expression:mammary gland RGD PMID:6030068 RGD:2303540 NCBI chr2A:27,218,699...27,245,156
Ensembl chr2A:27,306,527...27,332,804
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:18,297,434...18,444,011
Ensembl chr 1:19,344,154...19,488,133
JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr  X:33,967,329...34,374,385
Ensembl chr  X:41,659,295...42,066,570
JBrowse link
G CASP1 caspase 1 ISO RGD PMID:10557324 RGD:2315886 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
JBrowse link
G CASP3 caspase 3 treatment
severity
ISO RGD PMID:20732338, PMID:23404339, PMID:26699876 RGD:10053670, RGD:10053708, RGD:13782283 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP7 caspase 7 treatment ISO RGD PMID:23404339, PMID:23979166, PMID:26699876 RGD:10053670, RGD:13209143, RGD:13782283 NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626
JBrowse link
G CASP8 caspase 8 severity ISO RGD PMID:20732338 RGD:10053708 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G CASP9 caspase 9 severity
treatment
ISO RGD PMID:17297389, PMID:20012353, PMID:20732338, PMID:26699876 RGD:10053708, RGD:13782283, RGD:2315928, RGD:2315933 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266
JBrowse link
G CAV1 caveolin 1 onset
treatment
ISO protein:decreased expression:mammary gland RGD PMID:9685399, PMID:15334058, PMID:15355971 RGD:2289100, RGD:2289106, RGD:8661780 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CCNA2 cyclin A2 ISO protein:increased expression:mammary gland RGD PMID:10713672 RGD:2293347 NCBI chr 4:114,016,917...114,024,816
Ensembl chr 4:125,153,810...125,161,302
JBrowse link
G CCNB1 cyclin B1 ISO RGD PMID:11146550 RGD:2315939 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332
JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:mammary gland
RGD
CTD
PMID:12376462, PMID:12602925, PMID:12649181, PMID:14522882, PMID:16316942, PMID:17440082 RGD:2289336, RGD:2289337, RGD:2296037 NCBI chr11:64,737,006...64,750,353 JBrowse link
G CCND3 cyclin D3 ISO mRNA, protein:increased expression:mammary gland RGD PMID:12853979, PMID:16311245 RGD:2316015, RGD:2316020 NCBI chr 6:41,518,421...41,630,103
Ensembl chr 6:42,820,569...42,827,498
JBrowse link
G CCNE1 cyclin E1 ISO protein:decreased expression:mammary gland RGD PMID:12602925, PMID:12649181 RGD:2289336, RGD:2289337 NCBI chr19:26,739,285...26,751,630
Ensembl chr19:35,496,700...35,510,295
JBrowse link
G CCNH cyclin H ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:mammary gland
CTD
RGD
PMID:12606953 RGD:9590264 NCBI chr 5:27,958,859...27,995,815
Ensembl chr 5:28,094,064...28,116,149
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:21621198 RGD:6893427 NCBI chr 3:46,147,928...46,172,947
Ensembl chr 3:47,253,878...47,278,630
JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO RGD PMID:14597737, PMID:22637726 RGD:8551810, RGD:8551813 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379
JBrowse link
G CD40 CD40 molecule ISO RGD PMID:21137078 RGD:8547744 NCBI chr20:42,455,711...42,467,139
Ensembl chr20:43,541,619...43,552,994
JBrowse link
G CD44 CD44 molecule (Indian blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283680 NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009
JBrowse link
G CDC25A cell division cycle 25A ISO RGD PMID:16951165, PMID:17283130, PMID:17638870 RGD:2754551, RGD:2764000, RGD:2771824 NCBI chr 3:48,068,601...48,099,806
Ensembl chr 3:49,154,307...49,186,115
JBrowse link
G CDC42 cell division cycle 42 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G CDH1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488
JBrowse link
G CDH13 cadherin 13 severity ISO RGD PMID:18316604 RGD:2293540 NCBI chr16:63,255,482...64,418,053
Ensembl chr16:82,883,184...83,808,996
JBrowse link
G CDK2 cyclin dependent kinase 2 ISO RGD PMID:16924466 RGD:2293558 NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945
JBrowse link
G CDK4 cyclin dependent kinase 4 susceptibility ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:mammary gland
RGD
CTD
PMID:12376462, PMID:14522882, PMID:16413469, PMID:25221644 RGD:2293577, RGD:2293581 NCBI chr12:31,174,446...31,178,597
Ensembl chr12:31,434,594...31,438,876
JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25221644 NCBI chr 7:84,603,419...84,835,082 JBrowse link
G CDKL2 cyclin dependent kinase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25333262 NCBI chr 4:48,575,933...48,628,916
Ensembl chr 4:54,415,305...54,458,111
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B treatment ISO protein:increased expression:mammary gland RGD PMID:15844214, PMID:22651929 RGD:10045559, RGD:2293626 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A disease_progression ISO RGD PMID:18060046, PMID:20681787 RGD:2289674, RGD:8552689 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CDS1 CDP-diacylglycerol synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:39,530,229...39,598,543
Ensembl chr 4:45,379,856...45,448,170
JBrowse link
G CLU clusterin disease_progression ISO RGD PMID:23099883 RGD:8699504 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523
JBrowse link
G CNN3 calponin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:97,558,652...97,588,791
Ensembl chr 1:96,286,015...96,316,249
JBrowse link
G COL18A1 collagen type XVIII alpha 1 chain severity ISO RGD PMID:10766159 RGD:70690 NCBI chr21:31,720,358...31,834,470 JBrowse link
G COL5A1 collagen type V alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 9:105,746,388...105,956,280
Ensembl chr 9:134,342,955...134,544,651
JBrowse link
G CSF1 colony stimulating factor 1 ISO RGD PMID:15205327 RGD:2293710 NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943
JBrowse link
G CSN2 casein beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:9879772, PMID:16316942 NCBI chr 4:54,276,495...54,282,221
Ensembl chr 4:60,613,091...60,618,815
JBrowse link
G CSN3 casein kappa ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:53,972,361...53,981,203
Ensembl chr 4:60,315,922...60,324,767
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO RGD PMID:11827167 RGD:727632 NCBI chr20:689,494...752,092
Ensembl chr20:456,629...521,126
JBrowse link
G CTNNB1 catenin beta 1 ISO DNA:missense mutations: :p.S33Y, p.S45F
protein:increased expression:mammary gland
RGD PMID:17510243, PMID:18060046 RGD:2289674, RGD:2289816 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr2B:6,309,048...6,314,660 JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283680 NCBI chr 6:30,625,871...30,645,066
Ensembl chr 6:31,496,047...31,513,455
JBrowse link
G DES desmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr2B:106,675,761...106,684,129
Ensembl chr2B:225,266,261...225,273,604
JBrowse link
G DIO1 iodothyronine deiodinase 1 ISO RGD PMID:11765219 RGD:727335 NCBI chr 1:53,167,840...53,184,961
Ensembl chr 1:54,762,744...54,779,679
JBrowse link
G DNMT3B DNA methyltransferase 3 beta treatment ISO RGD PMID:24447120 RGD:9588304 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487
JBrowse link
G DUSP1 dual specificity phosphatase 1 treatment ISO RGD PMID:20837666 RGD:5129167 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960
JBrowse link
G DUSP6 dual specificity phosphatase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:86,875,289...86,879,731
Ensembl chr12:90,195,482...90,200,321
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 6:71,342,291...71,346,033 JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr2A:56,017,678...56,076,059
Ensembl chr2A:57,155,000...57,212,500
JBrowse link
G EGFR epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:2523869, PMID:8603490, PMID:17203220 RGD:2289979 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G EIF5A eukaryotic translation initiation factor 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr17:7,341,076...7,346,570
Ensembl chr17:7,327,363...7,333,270
JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:7,619,490...7,637,558 JBrowse link
G EPCAM epithelial cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr2A:47,490,748...47,508,418
Ensembl chr2A:48,413,520...48,432,038
JBrowse link
G EPHX1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:201,271,366...201,306,635
Ensembl chr 1:206,272,866...206,307,581
JBrowse link
G EPO erythropoietin treatment ISO RGD PMID:12118093 RGD:11041669 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974
JBrowse link
G EPOR erythropoietin receptor treatment ISO RGD PMID:12118093 RGD:11041669 NCBI chr19:10,925,148...10,931,955
Ensembl chr19:11,635,248...11,642,383
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO Androgen-dependent
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:1913683, PMID:8603490, PMID:12150826, PMID:17203220, PMID:25221644 RGD:2289920, RGD:2289979, RGD:6482679 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 ISO RGD PMID:17203220 RGD:2289979 NCBI chr12:32,811,533...32,834,958
Ensembl chr12:33,063,434...33,084,994
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:17203220 RGD:2289979 NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006
JBrowse link
G ESR1 estrogen receptor 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:epithelial cell, nucleus
CTD
RGD
PMID:11759285, PMID:15637090, PMID:18055862 RGD:2290019, RGD:8552983, RGD:8553057 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G ESR2 estrogen receptor 2 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:epithelial cell, nucleus
CTD
RGD
PMID:15637090, PMID:24078029 RGD:7364911, RGD:8552983 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303
JBrowse link
G EZR ezrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 6:156,656,146...156,709,986
Ensembl chr 6:161,670,483...161,723,102
JBrowse link
G F11R F11 receptor ISO RGD PMID:22120722 RGD:7488922 NCBI chr 1:136,399,766...136,424,722
Ensembl chr 1:140,324,943...140,346,890
JBrowse link
G FABP4 fatty acid binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 8:78,001,476...78,006,006
Ensembl chr 8:79,624,899...79,630,168
JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:18094967 RGD:2290047 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FBXO10 F-box protein 10 ISO RGD PMID:17404222 RGD:1601189 NCBI chr 9:37,355,861...37,421,321
Ensembl chr 9:38,279,653...38,345,040
JBrowse link
G FGF10 fibroblast growth factor 10 ISO mRNA:increased expression:mammary gland RGD PMID:18421211 RGD:2292665 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706
JBrowse link
G FGF8 fibroblast growth factor 8 ISO RGD PMID:9840935 RGD:2301098 NCBI chr10:98,372,251...98,378,811
Ensembl chr10:101,844,792...101,853,916
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO RGD PMID:10498246 RGD:2302211 NCBI chr13:9,283,747...9,381,553
Ensembl chr13:27,627,178...27,723,940
JBrowse link
G FN1 fibronectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr2B:102,623,568...102,698,747
Ensembl chr2B:221,208,431...221,284,003
JBrowse link
G FRMPD1 FERM and PDZ domain containing 1 ISO RGD PMID:17404222 RGD:1601189 NCBI chr 9:37,497,210...37,595,867
Ensembl chr 9:38,421,706...38,519,025
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462, PMID:16316942 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023
JBrowse link
G G0S2 G0/G1 switch 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:185,251,903...185,252,882
Ensembl chr 1:190,057,382...190,057,693
JBrowse link
G GATA3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G GATM glycine amidinotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr15:24,309,045...24,326,673
Ensembl chr15:42,639,597...42,657,209
JBrowse link
G GDA guanine deaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 9:52,559,752...52,662,886
Ensembl chr 9:70,891,319...70,994,574
JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr22:5,424,334...5,469,705 JBrowse link
G GNAI2 G protein subunit alpha i2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988
JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO RGD PMID:28810530 RGD:13792729 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G GSN gelsolin ISO mRNA:decreased expression RGD PMID:8895730 RGD:1599869 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831
JBrowse link
G GSS glutathione synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr20:31,256,734...31,284,356
Ensembl chr20:32,381,745...32,409,297
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:17280655 RGD:2293194 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:16319139, PMID:23215791 RGD:10755708 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:34,456,900...34,463,317
Ensembl chr12:35,184,943...35,188,443
JBrowse link
G HNRNPAB heterogeneous nuclear ribonucleoprotein A/B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15538050 NCBI chr 5:173,364,301...173,370,974 JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO DNA:mutation: :p.G12E (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8185828, PMID:11376698, PMID:19652463 RGD:2314834 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283680 NCBI chr20:27,895,177...27,896,414
Ensembl chr20:28,535,582...28,536,311
JBrowse link
G ID3 inhibitor of DNA binding 3, HLH protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:22,748,714...22,750,582
Ensembl chr 1:23,734,263...23,736,175
JBrowse link
G ID4 inhibitor of DNA binding 4, HLH protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:14633621 NCBI chr 6:19,665,197...19,668,517 JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15217511, PMID:15528971, PMID:17584969, PMID:23342276 RGD:8549490 NCBI chr12:99,986,887...100,066,773 JBrowse link
G IL10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14999141 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL18BP interleukin 18 binding protein ISO mRNA:increased expression:mammary gland RGD PMID:18959458 RGD:2313895 NCBI chr11:67,078,251...67,083,043
Ensembl chr11:70,302,923...70,307,511
JBrowse link
G IL6ST interleukin 6 signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 5:58,023,704...58,081,895
Ensembl chr 5:59,669,606...59,708,817
JBrowse link
G ILK integrin linked kinase ISO late onset development of tumors in transgenic mice overexpressing human ILK in mammary glands RGD PMID:11704830 RGD:2301733 NCBI chr11:6,735,735...6,742,922
Ensembl chr11:6,418,717...6,425,788
JBrowse link
G INSIG1 insulin induced gene 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012
JBrowse link
G ITGB3 integrin subunit beta 3 ISO protein:increased expression:mammary gland: RGD PMID:22022542 RGD:8693386 NCBI chr17:10,134,450...10,194,596 JBrowse link
G KDR kinase insert domain receptor ISO inhibition prevents DMBA-induced atypical ductal hyperplasia and carcinoma in situ RGD PMID:15170218, PMID:19888452 RGD:2291936, RGD:5684399 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO DNA:mutation (rat) RGD PMID:18445266 RGD:2302172 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473
JBrowse link
G KITLG KIT ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:86,036,501...86,124,274
Ensembl chr12:89,341,921...89,436,758
JBrowse link
G KRT5 keratin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:36,243,221...36,249,573
Ensembl chr12:37,021,432...37,025,105
JBrowse link
G KRT7 keratin 7 ISO RGD PMID:8570173 RGD:2317439 NCBI chr12:36,514,021...36,529,721
Ensembl chr12:37,291,244...37,307,341
JBrowse link
G KRT71 keratin 71 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:36,211,012...36,220,249
Ensembl chr12:36,988,665...36,997,215
JBrowse link
G LEP leptin treatment ISO RGD PMID:22246620 RGD:8694468 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO mRNA:splice variant (rat) RGD PMID:15044717 RGD:2302177 NCBI chr2A:48,808,822...48,879,021 JBrowse link
G LIN7A lin-7 homolog A, crumbs cell polarity complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:78,312,501...78,456,871
Ensembl chr12:81,442,152...81,567,522
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16619500 RGD:1582109 NCBI chr 5:92,247,060...92,348,900
Ensembl chr 5:97,842,110...97,893,876
JBrowse link
G LOC100971374 thioredoxin-interacting protein severity ISO mRNA:decreased expression:mammary gland RGD PMID:15170812 RGD:1642758 NCBI chr 1:90,007,878...90,012,055 JBrowse link
G LOC100971425 somatotropin treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:6139974, PMID:12082019, PMID:15528971, PMID:17584969 RGD:11352806, RGD:2315650 NCBI chr17:58,010,848...58,013,421 JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A susceptibility ISO CTD Direct Evidence: marker/mechanism
protein:altered localization:nucleus
protein:increased tyrosine phosphorylation:mammary gland
CTD
RGD
PMID:12082622, PMID:12376462, PMID:15609129, PMID:16316942, PMID:17173897 RGD:2291927, RGD:2291932, RGD:2298539 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783
JBrowse link
G LOC100988671 histone H3.3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr17:69,728,165...69,730,519
Ensembl chr17:75,277,614...75,281,106
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein treatment ISO human protein in a mouse model RGD PMID:21890879 RGD:6771361 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G LOC100994157 histone H2AX treatment ISO RGD PMID:22384017 RGD:7240549 NCBI chr11:113,932,078...113,933,679 JBrowse link
G LOC100995326 serotransferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9879772, PMID:16316942 NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476
JBrowse link
G LOC100995394 uncharacterized LOC100995394 ISO RGD PMID:9000125 RGD:2301094 Ensembl chr15:46,702,119...46,770,163 JBrowse link
G LPL lipoprotein lipase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 8:19,164,541...19,193,100
Ensembl chr 8:16,113,415...16,142,966
JBrowse link
G LSR lipolysis stimulated lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462, PMID:16316942 NCBI chr19:32,195,036...32,214,300
Ensembl chr19:40,932,180...40,951,448
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21317887 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:29435821 RGD:13800872 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:29435821 RGD:13800872 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MDH2 malate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 7:67,953,759...67,973,270
Ensembl chr 7:82,497,800...82,516,526
JBrowse link
G MGP matrix Gla protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462, PMID:16316942 NCBI chr12:14,887,806...14,891,796 JBrowse link
G MIF macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009
JBrowse link
G MMP1 matrix metallopeptidase 1 treatment ISO RGD PMID:19622769 RGD:8549722 NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104
JBrowse link
G MMP13 matrix metallopeptidase 13 severity ISO RGD PMID:18698413 RGD:2306081 NCBI chr11:97,890,811...97,902,778
Ensembl chr11:101,377,001...101,387,679
JBrowse link
G MMP15 matrix metallopeptidase 15 ISO mRNA:increased expression:mammary gland RGD PMID:15895410 RGD:2314949 NCBI chr16:38,304,856...38,326,193
Ensembl chr16:57,433,813...57,457,122
JBrowse link
G MMP2 matrix metallopeptidase 2 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:mammary gland
RGD
CTD
PMID:19725228, PMID:23359979, PMID:28574600 RGD:2325823, RGD:8657038 NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279
JBrowse link
G MMP3 matrix metallopeptidase 3 ISO RGD PMID:10428026 RGD:8662909 NCBI chr11:97,776,729...97,784,549
Ensembl chr11:101,267,566...101,275,354
JBrowse link
G MMP7 matrix metallopeptidase 7 onset ISO RGD PMID:9850086 RGD:9685350 NCBI chr11:97,467,037...97,477,305
Ensembl chr11:100,960,032...100,971,099
JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO mRNA, protein:increased expression:mammary gland
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19725228, PMID:21283680, PMID:23359979 RGD:2325823, RGD:8657038 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MPZL1 myelin protein zero like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:143,154,682...143,221,780
Ensembl chr 1:146,937,479...147,004,503
JBrowse link
G MRC2 mannose receptor C type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr17:56,692,163...56,757,966
Ensembl chr17:61,842,236...61,907,029
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:22349822 RGD:10040957 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G MUC1 mucin 1, cell surface associated treatment ISO RGD PMID:23015160 RGD:7349374 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor treatment ISO RGD PMID:22384017 RGD:7240549 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NCOA1 nuclear receptor coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21080969 NCBI chr2A:24,485,068...24,764,135
Ensembl chr2A:24,733,117...24,859,488
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 treatment ISO RGD PMID:22072621 RGD:10412719 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G NOTCH4 notch receptor 4 ISO RGD PMID:15531924 RGD:2299154 NCBI chr 6:31,842,233...31,871,412
Ensembl chr 6:32,722,112...32,750,978
JBrowse link
G NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 9:108,518,698...108,531,316
Ensembl chr 9:137,482,420...137,495,990
JBrowse link
G NUDT1 nudix hydrolase 1 ISO mRNA:increased expression:mammary gland RGD PMID:12036445 RGD:724605 NCBI chr 7:2,511,573...2,520,643
Ensembl chr 7:2,614,005...2,621,997
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:8647655, PMID:15089975 NCBI chr20:3,157,246...3,159,013 JBrowse link
G PADI4 peptidyl arginine deiminase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:16,255,680...16,311,256
Ensembl chr 1:17,311,436...17,365,426
JBrowse link
G PAK4 p21 (RAC1) activated kinase 4 ISO RGD PMID:20697354 RGD:7775027 NCBI chr19:36,224,442...36,278,371
Ensembl chr19:44,816,601...44,825,827
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 treatment ISO RGD PMID:23404339 RGD:10053670 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PCNA proliferating cell nuclear antigen ISO mRNA,protein:increased expression:mammary gland: RGD PMID:2567593 RGD:10448972 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G PCP4 Purkinje cell protein 4 ISO mRNA,protein:increased expression:cytoplasm: RGD PMID:19480007 RGD:9850273 NCBI chr21:26,069,039...26,284,247
Ensembl chr21:39,587,400...39,618,734
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462, PMID:16316942 NCBI chr 7:648,722...672,023 JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:115,716,953...115,726,412
Ensembl chr12:119,093,952...119,105,054
JBrowse link
G PGAM1 phosphoglycerate mutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:94,048,829...94,056,082
Ensembl chr10:97,542,558...97,549,867
JBrowse link
G PGR progesterone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15637090 NCBI chr11:95,997,677...96,098,866 JBrowse link
G PHB prohibitin ISO mRNA, protein:increased expression:mammary gland
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12376462 RGD:2292404 NCBI chr17:8,189,555...8,200,491 JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:22064478 RGD:8693420 NCBI chr19:9,389,829...9,404,099
Ensembl chr19:10,053,254...10,066,853
JBrowse link
G PKM pyruvate kinase M1/2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr15:51,149,584...51,182,193 JBrowse link
G PLAU plasminogen activator, urokinase disease_progression ISO RGD PMID:18052026 RGD:6484140 NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136
JBrowse link
G PLK2 polo like kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:11137312 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G PRDX2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr19:12,359,084...12,363,552
Ensembl chr19:13,103,422...13,107,369
JBrowse link
G PRL prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829
JBrowse link
G PRLR prolactin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 5:75,139,852...75,321,695
Ensembl chr 5:80,532,058...80,600,403
JBrowse link
G PSMA4 proteasome 20S subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr15:57,468,590...57,477,390
Ensembl chr15:76,431,890...76,440,655
JBrowse link
G PSME1 proteasome activator subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr14:4,912,390...4,915,219
Ensembl chr14:23,033,548...23,039,405
JBrowse link
G PTBP1 polypyrimidine tract binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr19:319,953...334,945 JBrowse link
G PTEN phosphatase and tensin homolog onset ISO RGD PMID:18381417 RGD:2292496 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G PTGER1 prostaglandin E receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11751431 NCBI chr19:14,035,876...14,038,812 JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO mRNA:increased expression:breast RGD PMID:18279516, PMID:18676768, PMID:21623034 RGD:2300118, RGD:2300130, RGD:5135030 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G PTK2 protein tyrosine kinase 2 disease_progression ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:15930288, PMID:18056629, PMID:24809783 RGD:2292554, RGD:2292560 NCBI chr 8:137,330,777...137,677,306
Ensembl chr 8:140,412,773...140,684,898
JBrowse link
G PTN pleiotrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623
JBrowse link
G RAN RAN, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462, PMID:16316942 NCBI chr12:128,497,407...128,503,049 JBrowse link
G RASA1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 5:27,980,907...28,104,368
Ensembl chr 5:28,115,159...28,240,321
JBrowse link
G RASGRF2 Ras protein specific guanine nucleotide releasing factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 5:34,048,832...34,326,755
Ensembl chr 5:34,359,896...34,635,488
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14522882 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
G RBP1 retinol binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:136,554,315...136,576,682
Ensembl chr 3:144,153,937...144,176,209
JBrowse link
G RBP4 retinol binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887
JBrowse link
G RCN1 reticulocalbin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr11:32,054,917...32,069,524 JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:decreased expression:peritoneal macrophage RGD PMID:16288051 RGD:2298764 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit ISO RGD PMID:16260626 RGD:7777148 NCBI chr19:41,948,559...41,987,121
Ensembl chr19:50,554,864...50,590,223
JBrowse link
G RNPEP arginyl aminopeptidase ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16619500 RGD:1582109 NCBI chr 1:177,579,349...177,602,865
Ensembl chr 1:181,880,404...181,903,906
JBrowse link
G RPL3 ribosomal protein L3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr22:20,216,370...20,223,259 JBrowse link
G RPL6 ribosomal protein L6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:110,002,667...110,008,899 JBrowse link
G RPS14 ribosomal protein S14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 5:145,869,410...145,875,038
Ensembl chr 5:151,873,605...151,879,128
JBrowse link
G RXRA retinoid X receptor alpha ISO RGD PMID:16344269 RGD:1643109 NCBI chr 9:105,424,046...105,539,241
Ensembl chr 9:134,082,865...134,144,704
JBrowse link
G S100A6 S100 calcium binding protein A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:128,889,749...128,891,425
Ensembl chr 1:132,518,834...132,520,499
JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:103,893,199...103,898,381
Ensembl chr 1:102,608,839...102,609,987
JBrowse link
G SCARB1 scavenger receptor class B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:122,293,803...122,455,314 JBrowse link
G SCD stearoyl-CoA desaturase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462, PMID:16316942 NCBI chr10:96,948,212...96,965,633 JBrowse link
G SELENOP selenoprotein P ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462, PMID:16316942 NCBI chr 5:67,570,087...67,582,192
Ensembl chr 5:72,619,607...72,627,213
JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 6:131,936,397...132,082,670
Ensembl chr 6:136,033,851...136,180,121
JBrowse link
G SLC12A2 solute carrier family 12 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 5:123,499,267...123,603,777
Ensembl chr 5:129,262,134...129,364,563
JBrowse link
G SLC25A10 solute carrier family 25 member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr17:76,171,759...76,180,484
Ensembl chr17:81,875,710...81,882,106
JBrowse link
G SNCG synuclein gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:83,383,566...83,391,064 JBrowse link
G SNRPD3 small nuclear ribonucleoprotein D3 polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr22:5,361,886...5,378,465
Ensembl chr22:22,227,328...22,246,676
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO mRNA:increased expression:mammary gland RGD PMID:18381452, PMID:20354188 RGD:21079418, RGD:2298899 NCBI chr16:10,196,432...10,198,205 JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO mRNA:increased expression:mammary gland RGD PMID:18381452 RGD:2298899 NCBI chr17:72,433,206...72,436,500
Ensembl chr17:77,983,389...77,984,066
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23964924 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
G SOX9 SRY-box transcription factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr17:66,028,737...66,034,122 JBrowse link
G SPINT2 serine peptidase inhibitor, Kunitz type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr19:35,354,043...35,384,063
Ensembl chr19:43,928,847...43,958,886
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:15318939 NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr17:70,809,931...70,813,191
Ensembl chr17:76,375,957...76,379,759
JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO RGD PMID:11325527 RGD:2291895 NCBI chr2B:78,270,642...78,316,074
Ensembl chr2B:196,186,906...196,232,280
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:16316942, PMID:17483332 RGD:2291914 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G STC2 stanniocalcin 2 ISO mRNA:increased expression:mammary gland RGD PMID:18959458 RGD:2313895 NCBI chr 5:168,668,851...168,681,274
Ensembl chr 5:175,575,419...175,587,832
JBrowse link
G STMN1 stathmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:25,159,241...25,165,535
Ensembl chr 1:26,208,731...26,230,925
JBrowse link
G TDG thymine DNA glycosylase ISO mRNA:increased expression:mammary gland tumor (mouse) RGD PMID:9794235 RGD:2317355 NCBI chr12:101,543,945...101,567,035
Ensembl chr12:104,938,519...104,961,284
JBrowse link
G TFF1 trefoil factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283680 NCBI chr21:28,669,323...28,673,556
Ensembl chr21:41,988,039...41,992,270
JBrowse link
G TGFA transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8603490 NCBI chr2A:70,510,727...70,617,628
Ensembl chr2A:71,625,196...71,731,461
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO RGD PMID:8466857 RGD:7394797 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO RGD PMID:12808151 RGD:737735 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO RGD PMID:12808151 RGD:737735 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856
JBrowse link
G THBS1 thrombospondin 1 ISO mRNA:increased expression:mammary gland RGD PMID:15459484 RGD:1626167 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170
JBrowse link
G THRSP thyroid hormone responsive ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr11:73,123,030...73,128,461
Ensembl chr11:76,747,547...76,747,987
JBrowse link
G TKT transketolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:53,168,426...53,199,003
Ensembl chr 3:54,389,549...54,420,704
JBrowse link
G TLE4 TLE family member 4, transcriptional corepressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 9:45,103,762...45,258,137
Ensembl chr 9:78,436,831...78,590,626
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:19755514 RGD:7401185 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO RGD PMID:17671220 RGD:2290495 NCBI chr 8:22,440,502...22,476,790
Ensembl chr 8:19,378,547...19,414,724
JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:21252285 NCBI chr 3:169,512,491...169,530,706
Ensembl chr 3:177,694,021...177,712,137
JBrowse link
G TP53 tumor protein p53 disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:17470299, PMID:18092324, PMID:24809783 RGD:2290539, RGD:2290577 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G TPM3 tropomyosin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462, PMID:16316942 NCBI chr 1:129,511,914...129,538,703
Ensembl chr 1:133,126,641...133,161,894
JBrowse link
G TRPS1 transcriptional repressor GATA binding 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 8:112,079,147...112,339,567 JBrowse link
G TSC22D1 TSC22 domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr13:25,597,530...25,743,522
Ensembl chr 3:198,325,494...198,469,869
JBrowse link
G TYMS thymidylate synthetase ISO RGD PMID:9635926 RGD:2315839 NCBI chr18:13,653,085...13,668,478
Ensembl chr18:17,295,182...17,310,320
JBrowse link
G UBE2I ubiquitin conjugating enzyme E2 I ISO CTD Direct Evidence: marker/mechanism
MCF-7 human breast cancer cell tumors grown in nude mice
CTD
RGD
PMID:15735760, PMID:16316942 RGD:2301345 Ensembl chr16:1,367,288...1,382,575 JBrowse link
G UCP2 uncoupling protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr11:69,047,397...69,056,056
Ensembl chr11:72,354,529...72,363,185
JBrowse link
G VAMP8 vesicle associated membrane protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr2A:85,627,678...85,632,205
Ensembl chr2A:87,180,681...87,185,195
JBrowse link
G VDR vitamin D receptor ISO RGD PMID:15333467 RGD:8158073 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192
JBrowse link
G VEGFA vascular endothelial growth factor A treatment ISO human protein in a mouse model RGD PMID:21890879 RGD:6771361 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
G WNT1 Wnt family member 1 ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359, PMID:9419423 RGD:2298848, RGD:2298863 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583
JBrowse link
G WNT2 Wnt family member 2 ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359, PMID:9419423 RGD:2298848, RGD:2298863 NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862
JBrowse link
G WNT3 Wnt family member 3 ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:9419423 RGD:2298848 NCBI chr17:10,685,160...10,741,402
Ensembl chr17:10,862,310...10,918,865
JBrowse link
G WNT3A Wnt family member 3A ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359, PMID:9419423 RGD:2298848, RGD:2298863 NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469
JBrowse link
G WNT5B Wnt family member 5B no_association ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359, PMID:9419423 RGD:2298848, RGD:2298863 NCBI chr12:1,633,987...1,757,431
Ensembl chr12:1,691,097...1,708,351
JBrowse link
G WNT6 Wnt family member 6 no_association ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359, PMID:9419423 RGD:2298848, RGD:2298863 NCBI chr2B:106,119,740...106,134,317
Ensembl chr2B:224,714,229...224,728,171
JBrowse link
G WNT7A Wnt family member 7A ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359, PMID:9419423 RGD:2298848, RGD:2298863 NCBI chr 3:13,733,487...13,797,189
Ensembl chr 3:14,077,839...14,138,386
JBrowse link
G WNT7B Wnt family member 7B no_association ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359, PMID:9419423 RGD:2298848, RGD:2298863 Ensembl chr22:44,988,647...45,044,841 JBrowse link
G XDH xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455
JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO CTD Direct Evidence: therapeutic CTD PMID:12766084 NCBI chr  X:113,052,164...113,105,160
Ensembl chr  X:123,232,643...123,278,606
JBrowse link
G XRCC3 X-ray repair cross complementing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283680 NCBI chr14:84,323,644...84,341,763
Ensembl chr14:104,131,903...104,149,037
JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 8:97,560,251...97,595,117 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12749
    Animal Diseases 1164
      Animal Mammary Neoplasms 287
        Mammary Neoplasms, Experimental 271
Path 2
Term Annotations click to browse term
  disease 12749
    disease of anatomical entity 12279
      nervous system disease 10025
        sensory system disease 4755
          skin disease 2513
            breast disease 1059
              Breast Neoplasms 1050
                Animal Mammary Neoplasms 287
                  Mammary Neoplasms, Experimental 271
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.