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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Chronic Brain Injury
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Accession:DOID:9005179 term browser browse the term
Definition:Conditions characterized by persistent brain damage or dysfunction as sequelae of cranial trauma. This disorder may result from DIFFUSE AXONAL INJURY; INTRACRANIAL HEMORRHAGES; BRAIN EDEMA; and other conditions. Clinical features may include DEMENTIA; focal neurologic deficits; PERSISTENT VEGETATIVE STATE; AKINETIC MUTISM; or COMA.
Synonyms:exact_synonym: Chronic Brain Injuries
 primary_id: MESH:D020208


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Chronic Brain Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E susceptibility ISO DNA:polymorphism:exon: RGD PMID:9214529 RGD:7495763 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G TARDBP TAR DNA binding protein ISO protein:increased expression:brain RGD PMID:20720505 RGD:5687179 NCBI chr 6:71,213,584...71,227,707
Ensembl chr 6:71,213,860...71,227,704 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17412
    Wounds and Injuries 937
      Nervous System Trauma 575
        Craniocerebral Trauma 350
          Brain Injuries 278
            Chronic Brain Injury 2
              chronic traumatic encephalopathy 0
Path 2
Term Annotations click to browse term
  disease 17412
    disease of anatomical entity 14873
      nervous system disease 12960
        Nervous System Trauma 575
          Craniocerebral Trauma 350
            Brain Injuries 278
              Chronic Brain Injury 2
                chronic traumatic encephalopathy 0
paths to the root