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ONTOLOGY REPORT - ANNOTATIONS
Term:Cushing Syndrome
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Accession:DOID:9005158 term browser browse the term
Definition:A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
Synonyms:exact_synonym: Cushing syndrome;   Cushing's syndrome;   hypercortisolism
 primary_id: MESH:D003480
 alt_id: DOID:12252;   RDO:0005304
For additional species annotation, visit the Alliance of Genome Resources.

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Cushing Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Avpr1b arginine vasopressin receptor 1B JBrowse link 13 48,367,307 48,378,831 RGD:14700670
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:11554173
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 JBrowse link 10 27,847,447 27,862,896 RGD:1626491
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:8554872
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:7174715
RGD:7174723
RGD:7174722
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:11554173
G Prkacb protein kinase cAMP-activated catalytic subunit beta JBrowse link 2 252,602,197 252,691,886 RGD:11554173
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha JBrowse link 10 97,940,705 97,959,199 RGD:1581269
RGD:11554173
ACTH-Independent Macronodular Adrenal Hyperplasia 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Armc5 armadillo repeat containing 5 JBrowse link 1 199,655,069 199,662,419 RGD:11554173
G Gcgr glucagon receptor JBrowse link 10 109,707,863 109,716,253 RGD:11554173
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:7240710
RGD:8554872
RGD:11568052
ACTH-Independent Macronodular Adrenal Hyperplasia 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Armc5 armadillo repeat containing 5 JBrowse link 1 199,655,069 199,662,419 RGD:7240710
RGD:8554872
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15553
    syndrome 5224
      Cushing Syndrome 10
        ACTH-Independent Macronodular Adrenal Hyperplasia 1 3
        ACTH-Independent Macronodular Adrenal Hyperplasia 2 1
        ectopic Cushing syndrome 0
Path 2
Term Annotations click to browse term
  disease 15553
    disease of anatomical entity 14837
      endocrine system disease 4808
        adrenal gland disease 170
          adrenal cortex disease 75
            adrenal gland hyperfunction 31
              Cushing Syndrome 10
                ACTH-Independent Macronodular Adrenal Hyperplasia 1 3
                ACTH-Independent Macronodular Adrenal Hyperplasia 2 1
                ectopic Cushing syndrome 0
paths to the root

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