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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Microscopic Polyangiitis
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Accession:DOID:9005070 term browser browse the term
Definition:A primary systemic vasculitis of small- and some medium-sized vessels. It is characterized by a tropism for kidneys and lungs, positive association with anti-neutrophil cytoplasmic antibodies (ANCA), and a paucity of immunoglobulin deposits in vessel walls.
Synonyms:exact_synonym: Microscopic Polyangiitides
 primary_id: MESH:D055953;   RDO:0007726
For additional species annotation, visit the Alliance of Genome Resources.

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Microscopic Polyangiitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cl1 C-X3-C motif chemokine ligand 1 severity ISO protein:increased expression:serum RGD PMID:19327232 RGD:9491765 NCBI chrNW_004936475:9,443,851...9,454,715 JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:increased expression:blood, T cell RGD PMID:19327232 RGD:9491765 NCBI chrNW_004936473:28,508,726...28,535,640 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13007
    syndrome 6936
      primary immunodeficiency disease 2173
        autoimmune disease 1407
          Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 27
            Microscopic Polyangiitis 2
Path 2
Term Annotations click to browse term
  disease 13007
    disease of anatomical entity 12685
      nervous system disease 10539
        central nervous system disease 9228
          brain disease 8666
            cerebrovascular disease 746
              Cerebral Small Vessel Diseases 28
                Microscopic Polyangiitis 2
paths to the root