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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Microscopic Polyangiitis
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Accession:DOID:9005070 term browser browse the term
Definition:A primary systemic vasculitis of small- and some medium-sized vessels. It is characterized by a tropism for kidneys and lungs, positive association with anti-neutrophil cytoplasmic antibodies (ANCA), and a paucity of immunoglobulin deposits in vessel walls.
Synonyms:exact_synonym: Microscopic Polyangiitides
 primary_id: MESH:D055953
 xref: EFO:1000784


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Microscopic Polyangiitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CX3CL1 C-X3-C motif chemokine ligand 1 severity ISO protein:increased expression:serum RGD PMID:19327232 RGD:9491765 NCBI chr16:37,646,447...37,659,078
Ensembl chr16:56,779,065...56,791,760 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO protein:increased expression:blood, T cell RGD PMID:19327232 RGD:9491765 NCBI chr 3:39,158,346...39,176,604
Ensembl chr 3:39,440,955...39,457,219 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17996
    disease of anatomical entity 15260
      immune system disease 4393
        autoimmune disease 2024
          Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 32
            Microscopic Polyangiitis 2
Path 2
Term Annotations click to browse term
  disease 17996
    disease of anatomical entity 15260
      Immune & Inflammatory Diseases 5048
        immune system disease 4393
          primary immunodeficiency disease 3796
            autoimmune disease 2024
              Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 32
                Microscopic Polyangiitis 2
paths to the root