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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Microscopic Polyangiitis
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Accession:DOID:9005070 term browser browse the term
Definition:A primary systemic vasculitis of small- and some medium-sized vessels. It is characterized by a tropism for kidneys and lungs, positive association with anti-neutrophil cytoplasmic antibodies (ANCA), and a paucity of immunoglobulin deposits in vessel walls.
Synonyms:exact_synonym: Microscopic Polyangiitides
 primary_id: MESH:D055953;   RDO:0007726
For additional species annotation, visit the Alliance of Genome Resources.

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Microscopic Polyangiitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cl1 C-X3-C motif chemokine ligand 1 severity ISO protein:increased expression:serum RGD PMID:19327232 RGD:9491765 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
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G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:increased expression:blood, T cell RGD PMID:19327232 RGD:9491765 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17014
    syndrome 7758
      primary immunodeficiency disease 2537
        autoimmune disease 1774
          Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 30
            Microscopic Polyangiitis 2
Path 2
Term Annotations click to browse term
  disease 17014
    disease of anatomical entity 16363
      nervous system disease 11947
        central nervous system disease 10253
          brain disease 9616
            cerebrovascular disease 819
              Cerebral Small Vessel Diseases 37
                Microscopic Polyangiitis 2
paths to the root