Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Painful Neuropathy
go back to main search page
Accession:DOID:9004974 term browser browse the term
Synonyms:primary_id: MESH:C564945
 alt_id: RDO:0013734
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Painful Neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO
IEP
protein:increased expression:medulla oblongata, dorsal horn of spinal cord (mouse)
protein:increased expression:ipsilateral side, dorsal root ganglion (rat)
RGD PMID:22721162 PMID:15041200 RGD:8548831, RGD:8548884 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ep300 E1A binding protein p300 treatment IMP
IEP
mRNA:increased expression:lumbar spinal cord (rat) RGD PMID:23176208 PMID:23176208 RGD:7327202, RGD:7327202 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Hmgb1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27474498 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Thbd thrombomodulin ISO CTD Direct Evidence: therapeutic CTD PMID:27474498 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Tlr4 toll-like receptor 4 treatment ISO RGD PMID:18615568 RGD:7815041 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor ISO
IMP
protein:increased expression:Schwann cell RGD PMID:11376190 PMID:10825476 PMID:9514564 PMID:18394803 RGD:7394735, RGD:7394741, RGD:7394740, RGD:7394739 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17205
    disease of anatomical entity 16551
      nervous system disease 12097
        peripheral nervous system disease 2533
          Painful Neuropathy 6
Path 2
Term Annotations click to browse term
  disease 17205
    disease of anatomical entity 16551
      nervous system disease 12097
        Neurologic Manifestations 5444
          Pain 306
            Painful Neuropathy 6
paths to the root