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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Ocular Toxoplasmosis
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Accession:DOID:9004945 term browser browse the term
Definition:Infection caused by the protozoan parasite TOXOPLASMA in which there is extensive connective tissue proliferation, the retina surrounding the lesions remains normal, and the ocular media remain clear. Chorioretinitis may be associated with all forms of toxoplasmosis, but is usually a late sequel of congenital toxoplasmosis. The severe ocular lesions in infants may lead to blindness.
Synonyms:exact_synonym: ocular toxoplasmoses
 primary_id: MESH:D014126
 xref: EFO:0007399


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show annotations for term's descendants           Sort by:
Ocular Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 ISO RGD PMID:22740770 RGD:7421536 NCBI chrNW_004624811:765,338...782,203
Ensembl chrNW_004624811:764,940...782,198
JBrowse link
G Il10 interleukin 10 ISO RGD PMID:19026704 RGD:7365028 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
JBrowse link
G Il17a interleukin 17A treatment ISO protein:increased expression:aqueous humor (human) RGD PMID:22927448 RGD:8698652 NCBI chrNW_004624855:3,911,349...3,914,214
Ensembl chrNW_004624855:3,911,349...3,913,136
JBrowse link
G Il27 interleukin 27 disease_progression ISO mRNA:increased expression:eye, cervical lymph node (mouse) RGD PMID:29779048 RGD:126790500 NCBI chrNW_004624782:13,009,450...13,015,548
Ensembl chrNW_004624782:13,009,564...13,015,440
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:snp:3' utr:g.*397A>C (rs3135499)(human) RGD PMID:23100559 RGD:8547527 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14230
    disease by infectious agent 1935
      parasitic infectious disease 267
        Parasitic Eye Infections 13
          Ocular Toxoplasmosis 5
Path 2
Term Annotations click to browse term
  disease 14230
    Pathological Conditions, Signs and Symptoms 11246
      Signs and Symptoms 9467
        Neurologic Manifestations 9169
          sensory system disease 6536
            eye disease 3371
              Eye Infections 50
                Parasitic Eye Infections 13
                  Ocular Toxoplasmosis 5
paths to the root