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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Paranoid Disorders
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Accession:DOID:9004890 term browser browse the term
Definition:Chronic mental disorders in which there has been an insidious development of a permanent and unshakeable delusional system (persecutory delusions or delusions of jealousy), accompanied by preservation of clear and orderly thinking. Emotional responses and behavior are consistent with the delusional state.
Synonyms:exact_synonym: Paranoia;   Paranoias;   Paranoid Disorder;   Paranoid Psychoses
 primary_id: MESH:D010259;   RDO:0006285



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Paranoid Disorders term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c6 aldo-keto reductase family 1, member C6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22356824 NCBI chr13:4,484,354...4,507,529
Ensembl chr13:4,484,305...4,507,876
JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO associated with cocaine dependence; DNA:SNPs,haplotypes:multiple RGD PMID:21656904 RGD:401940117 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Dbh dopamine beta hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10673769 PMID:12555232 PMID:17157269 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212
JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 susceptibility ISO CTD Direct Evidence: marker/mechanism
associated with cocaine dependence; DNA:SNP:: (rs1738240) (human)
CTD
RGD
PMID:18438686 PMID:18438686 RGD:401851917 NCBI chr17:30,845,909...31,094,736
Ensembl chr17:30,843,328...31,096,339
JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
associated with cocaine dependence;DNA:SNP:: (rs936013) (human)
CTD
RGD
PMID:18438686 PMID:18438686 RGD:401851917 NCBI chr 9:69,305,185...69,340,360
Ensembl chr 9:69,305,188...69,340,404
JBrowse link
G Manea mannosidase, endo-alpha susceptibility ISO CTD Direct Evidence: marker/mechanism
associated with cocaine dependence;DNA:SNPs:multiple
associated with cocaine dependence; DNA:SNP:3'utr: (rs1133503) (human)
CTD
RGD
PMID:18438686 PMID:19255376 PMID:18438686 RGD:401851915, RGD:401851917 NCBI chr 4:26,324,506...26,346,913
Ensembl chr 4:26,324,506...26,346,891
JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8825631 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791
JBrowse link
G Tyk2 tyrosine kinase 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
associated with cocaine dependence; DNA:SNP:: (rs280521) (human)
CTD
RGD
PMID:18438686 PMID:18438686 RGD:401851917 NCBI chr 9:21,015,364...21,042,689
Ensembl chr 9:21,015,364...21,042,539
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  disease 18300
    disease of anatomical entity 15630
      nervous system disease 13500
        central nervous system disease 12085
          brain disease 11342
            disease of mental health 8197
              Schizophrenia Spectrum and Other Psychotic Disorders 1179
                Paranoid Disorders 8
paths to the root