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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Cardiovirus Infections
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Accession:DOID:9004531 term browser browse the term
Definition:Infections caused by viruses of the genus CARDIOVIRUS, family PICORNAVIRIDAE.
Synonyms:exact_synonym: Cardiovirus infection;   Cardiovirus infectious disease
 xref: EFO:0007194;   MESH:D018188;   MONDO:0005691


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Cardiovirus Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 ISO encephalomyocarditis virus;mRNA, protein:decreased expression, increased expression:heart (mouse) RGD PMID:19453650 RGD:40818405 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 ISO RGD PMID:21636578 RGD:40902809 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 susceptibility ISO RGD PMID:27999109 PMID:27999109 RGD:12910492, RGD:12910492 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,387...33,359,864 		JBrowse link
G IL33 interleukin 33 ISO mRNA:increased expression:brain: RGD PMID:18552204 RGD:40400716 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G PDE12 phosphodiesterase 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26055709 NCBI chr 3:57,556,274...57,656,495
Ensembl chr 3:57,556,274...57,656,480 		JBrowse link
G RNASEL ribonuclease L ISO RGD PMID:21636578 RGD:40902809 NCBI chr 1:182,573,634...182,589,256
Ensembl chr 1:182,573,634...182,589,256 		JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:10609881 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 97387
    disease by infectious agent 4422
      viral infectious disease 3242
        RNA Virus Infections 2617
          Picornaviridae Infections 70
            Cardiovirus Infections 7
paths to the root