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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Cardiovirus Infections
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Accession:DOID:9004531 term browser browse the term
Definition:Infections caused by viruses of the genus CARDIOVIRUS, family PICORNAVIRIDAE.
Synonyms:exact_synonym: Cardiovirus Infection
 primary_id: MESH:D018188;   RDO:0007096
For additional species annotation, visit the Alliance of Genome Resources.


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Cardiovirus Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 ISO encephalomyocarditis virus;mRNA, protein:decreased expression, increased expression:heart (mouse) RGD PMID:19453650 RGD:40818405 NCBI chr  X:30,293,597...30,340,961 JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 ISO RGD PMID:21636578 RGD:40902809 NCBI chr 6:16,189,000...16,224,972 JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 susceptibility IMP RGD PMID:27999109, PMID:27999109 RGD:12910492, RGD:12910492 NCBI chr11:30,725,774...30,752,227 JBrowse link
G Ifnar1em1 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 1 IMP RGD PMID:27999109 RGD:12910492
G Ifnar1em2 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 2 IMP RGD PMID:27999109 RGD:12910492
G Il33 interleukin 33 ISO mRNA:increased expression:brain: RGD PMID:18552204 RGD:40400716 NCBI chr 1:227,701,964...227,736,374 JBrowse link
G Pde12 phosphodiesterase 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26055709 NCBI chr16:1,915,386...1,925,427 JBrowse link
G Rnasel ribonuclease L ISO RGD PMID:21636578 RGD:40902809 NCBI chr13:65,894,990...65,910,354 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:10609881 NCBI chr20:3,622,011...3,624,629 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  disease 17160
    disease by infectious agent 1911
      viral infectious disease 1565
        RNA Virus Infections 1351
          Picornaviridae Infections 83
            Cardiovirus Infections 11
paths to the root