Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Sepsis
go back to main search page
Accession:DOID:9004484 term browser browse the term
Definition:Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Synonyms:exact_synonym: Blood Poisoning;   Pyaemia;   Pyaemias;   Pyemia;   Pyemias;   Pyohemia;   Pyohemias;   Septicemia;   Septicemias;   blood poisonings
 narrow_synonym: septic shock;   severe sepsis
 related_synonym: SEPSIS, SUSCEPTIBILITY TO
 primary_id: MESH:D018805
 xref: EFO:0001420


show annotations for term's descendants           Sort by:
Sepsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin ISO mRNA:increased expression:liver RGD PMID:9843780 PMID:15167684 RGD:1598509, RGD:10046033 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186 		JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase severity ISO DNA:polymorphism:cds:allele A (human) RGD PMID:4375858 RGD:39938844 NCBI chr 2:26,732,508...26,754,973
Ensembl chr 2:26,732,515...26,754,991 		JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:insertion/deletion:intron: RGD PMID:19143971 RGD:40400706 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO
IMP
IEP		 mRNA, protein:decreasedexpression:serum, omental fat pad: RGD PMID:16488436 PMID:19481767 PMID:21962804 RGD:1599144, RGD:5686835, RGD:5686408 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adm adrenomedullin treatment ISO protein:increased expression:plasma:
CTD Direct Evidence: marker/mechanism
associated with Jaundice,Obstructive;		 CTD
RGD		 PMID:14766677 PMID:20132852 PMID:19009024 PMID:20132852 RGD:7364952, RGD:7364986, RGD:7364952 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27757725 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618 		JBrowse link
G Adora2b adenosine A2b receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27757725 NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279 		JBrowse link
G Adra2a adrenergic receptor, alpha 2a disease_progression ISO RGD PMID:19894027 RGD:6480483 NCBI chr19:54,033,690...54,037,413
Ensembl chr19:54,032,582...54,037,413 		JBrowse link
G Adrb2 adrenergic receptor, beta 2 ISO mRNA,protein:decreased expression:liver: RGD PMID:16603198 PMID:10409266 RGD:1598745, RGD:8548498 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Adrb3 adrenergic receptor, beta 3 ISO mRNA, protein:increased expression:heart left ventricle (human) RGD PMID:17999941 RGD:2292119 NCBI chr 8:27,715,804...27,720,833
Ensembl chr 8:27,715,804...27,740,644 		JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment ISO RGD PMID:19623040 RGD:10402067 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Alas1 aminolevulinic acid synthase 1 ISO mRNA:increased expression:duodenum, jejunum, ileum (rat) RGD PMID:12627002 RGD:4144178 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853 		JBrowse link
G Alb albumin disease_progression ISO protein:decreased expression:serum: RGD PMID:22801198 RGD:11036079 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial treatment ISO associated with heat shock treatment;protein:altered expression, altered phosphorylation:liver, mitochondria (rat) RGD PMID:17607160 RGD:15036802 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Angpt1 angiopoietin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16005988 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373 		JBrowse link
G Apoa1 apolipoprotein A-I treatment ISO RGD PMID:19561306 RGD:7241869 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Arg2 arginase type II ISO protein:decreased expression:lung RGD PMID:9635249 RGD:1626297 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075 		JBrowse link
G Atm ataxia telangiectasia mutated treatment IMP RGD PMID:24184056 RGD:126781746 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 ISO RGD PMID:28446393 RGD:13782063 NCBI chr 7:126,045,032...126,062,245
Ensembl chr 7:126,045,030...126,062,280 		JBrowse link
G Baat bile acid-Coenzyme A: amino acid N-acyltransferase ISO RGD PMID:7575455 RGD:69770 NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment ISO protein:increased localization:mitochondrion RGD PMID:24011917 PMID:22683079 RGD:10053647, RGD:10053707 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G C3 complement component 3 ISO
IEP		 protein:increased expression:liver
mRNA:increased expression:kidney		 RGD PMID:3339873 PMID:24154627 RGD:7411622, RGD:11040886 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G C5ar1 complement component 5a receptor 1 disease_progression ISO RGD PMID:12897064 PMID:18648551 RGD:5130176, RGD:5130170 NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465 		JBrowse link
G C6 complement component 6 severity ISO RGD PMID:15638131 RGD:1600672 NCBI chr15:4,756,550...4,833,527
Ensembl chr15:4,756,657...4,844,449 		JBrowse link
G Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit ISO protein:decreased expression:diaphragmaticus muscle RGD PMID:28044347 RGD:329849111 NCBI chr 1:135,980,549...136,047,268
Ensembl chr 1:135,980,488...136,047,560 		JBrowse link
G Camp cathelicidin antimicrobial peptide ISO RGD PMID:17142779 RGD:2316243 NCBI chr 9:109,676,445...109,678,524
Ensembl chr 9:109,676,447...109,678,685 		JBrowse link
G Casp3 caspase 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16003065 PMID:32062619 PMID:29180187 RGD:13782295 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp6 caspase 6 ISO protein:increased activity:thymus, T cell RGD PMID:11086028 RGD:2301332 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752 		JBrowse link
G Casp8 caspase 8 treatment ISO RGD PMID:18570579 PMID:29180187 RGD:2311435, RGD:13782295 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:29180187 RGD:13782295 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cast calpastatin ISO RGD PMID:15563579 RGD:5683871 NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929 		JBrowse link
G Cat catalase severity ISO RGD PMID:15836852 RGD:9068893 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cbs cystathionine beta-synthase susceptibility ISO DNA:SNP:intron (rs6586282, rs34758144) (human) RGD PMID:26508567 RGD:40903018 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 ISO RGD PMID:21652218 RGD:7248417 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO mRNA:increased expression:ileum RGD PMID:19111613 RGD:2307002 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 severity ISO RGD PMID:21208283 RGD:5683911 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased secretion:plasma (rat) RGD PMID:18290317 RGD:4890036 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Cd163 CD163 antigen ISO protein:increased expression:blood serum, CD-14 positive monocyte (human) RGD PMID:24637679 RGD:127285802 NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486 		JBrowse link
G Cd1d1 CD1d1 antigen treatment IMP RGD PMID:14572776 RGD:127345103 NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748 		JBrowse link
G Cd209a CD209a antigen IMP RGD PMID:23254286 RGD:39938991 NCBI chr 8:3,793,395...3,798,984
Ensembl chr 8:3,793,397...3,798,984 		JBrowse link
G Cd274 CD274 antigen disease_progression ISO protein:increased expression:monocyte
protein:increased expression:B cell,CD4T cell		 RGD PMID:30595665 PMID:27156867 PMID:29702526 PMID:29661225 RGD:40818235, RGD:41412183, RGD:40822808, RGD:40818424 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Cd28 CD28 antigen severity ISO Higher soluble CD28 in human patients that died RGD PMID:17989345 RGD:5131622 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cd36 CD36 molecule IMP RGD PMID:22327076 RGD:6893490 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cd40 CD40 antigen ISO protein:decreased nitrosylation:monocyte RGD PMID:20473113 RGD:5490974 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd40lg CD40 ligand ISO mRNA:increased expression:heart (rat) RGD PMID:20933523 RGD:11352671 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO RGD PMID:10451498 RGD:10043817 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO protein:increased expression:skeletal muscle RGD PMID:11792653 RGD:625506 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta ISO protein:increased expression:skeletal muscle RGD PMID:11792653 RGD:625506 NCBI chr16:15,705,150...15,707,409
Ensembl chr16:15,705,150...15,708,895 		JBrowse link
G Cfb complement factor B treatment IMP RGD PMID:24154627 RGD:11040886 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494 		JBrowse link
G Cfh complement component factor h treatment ISO protein:decreased expression:plasma:
associated with Jaundice,Obstructive;		 RGD PMID:20132852 PMID:19009024 PMID:20132852 RGD:7364952, RGD:7364986, RGD:7364952 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502 		JBrowse link
G Cpb2 carboxypeptidase B2 ISO protein:increased activity:plasma: RGD PMID:15497025 RGD:2313648 NCBI chr14:75,479,727...75,520,995
Ensembl chr14:75,479,727...75,520,995 		JBrowse link
G Crh corticotropin releasing hormone ISO protein:increased expression:hypothalamus (rat) RGD PMID:21549066 RGD:5490558 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:blood: RGD PMID:21797109 PMID:19060982 RGD:6482315, RGD:9491784 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Cs citrate synthase ISO protein:decreased expression:cerebral cortex RGD PMID:25299715 RGD:329337347 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) ISO protein:increased expression:plasma: RGD PMID:10664226 RGD:10449523 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) treatment ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:17505274 PMID:8706460 RGD:11039434 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:increased expression:lung, macrophage RGD PMID:19733456 RGD:4144897 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,877,749...119,898,945 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 exacerbates ISO protein:increased expression:blood plasma (human) RGD PMID:31818332 RGD:40924635 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IMP RGD PMID:9284162 RGD:5135255 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 IEP protein:increased expression:multiple tissues RGD PMID:9284162 RGD:5135255 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17138957 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO mRNA, protein:decreased expression:liver RGD PMID:15665729 RGD:5147745 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO RGD PMID:18360687 PMID:15665729 RGD:2303376, RGD:5147745 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 ISO RGD PMID:15665729 RGD:5147745 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO RGD PMID:15665729 RGD:5147745 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp2j6 cytochrome P450, family 2, subfamily j, polypeptide 6 ISO RGD PMID:15190971 RGD:1625384 NCBI chr 4:96,404,375...96,449,835
Ensembl chr 4:96,404,375...96,441,898 		JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 ISO RGD PMID:15190971 RGD:1625384 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815 		JBrowse link
G Defb2 defensin beta 2 treatment ISO RGD PMID:17177330 RGD:9685178 NCBI chr 8:22,329,942...22,333,519
Ensembl chr 8:22,329,942...22,333,498 		JBrowse link
G Edn1 endothelin 1 ISO mRNA, protein:increased expression:multiple (rat) RGD PMID:10838194 RGD:8662298 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B, subunit 5 epsilon ISO protein:increased serine phosphorylation:gastrocnemius RGD PMID:12376332 RGD:11041880 NCBI chr16:20,317,544...20,328,073
Ensembl chr16:20,317,567...20,328,073 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha ISO RGD PMID:8141277 RGD:10395355 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E ISO RGD PMID:17709445 RGD:10401144 NCBI chr 3:138,231,952...138,265,457
Ensembl chr 3:138,231,940...138,265,457 		JBrowse link
G Elane elastase, neutrophil expressed IMP associated with Klebsiella Infections; RGD PMID:9585238 RGD:10450543 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 ISO protein:increased activity:lymphocyte: RGD PMID:22645477 RGD:9685487 NCBI chr19:40,600,810...40,730,046
Ensembl chr19:40,600,810...40,730,046 		JBrowse link
G Ep300 E1A binding protein p300 ISO mRNA, protein:increased expression:muscle part of extensor digitorum longus (rat) RGD PMID:20538901 RGD:7364733 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Esr2 estrogen receptor 2 (beta) ISO RGD PMID:16755255 RGD:5508850 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G F11 coagulation factor XI ISO RGD PMID:12000738 RGD:1598921 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068 		JBrowse link
G F2 coagulation factor II treatment ISO RGD PMID:19705256 PMID:12361199 RGD:7387324, RGD:10449428 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G F3 coagulation factor III treatment ISO RGD PMID:9875912 PMID:26311287 RGD:11340217, RGD:11341736 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G F5 coagulation factor V severity
treatment		 ISO RGD PMID:16235188 PMID:12000738 RGD:4892622, RGD:1598921 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846 		JBrowse link
G F7 coagulation factor VII treatment ISO protein:decreased activity:plasma (rat) RGD PMID:3660344 PMID:12000738 RGD:2312320, RGD:1598921 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G F9 coagulation factor IX treatment ISO RGD PMID:12000738 RGD:1598921 NCBI chr  X:59,044,675...59,076,120
Ensembl chr  X:59,044,824...59,076,119 		JBrowse link
G Fas Fas cell surface death receptor ISO mRNA:increased expression:liver RGD PMID:17899301 RGD:2290175 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand ISO mRNA:increased expression:liver RGD PMID:17899301 RGD:2290175 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fga fibrinogen alpha chain ISO protein:decreased expression:serum (rat) RGD PMID:24667622 RGD:9685020 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 disease_progression ISO Pneumonia associated sepsis RGD PMID:21219633 RGD:4891938 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Foxp3 forkhead box P3 severity ISO RGD PMID:25403265 RGD:38455982 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Fyn Fyn proto-oncogene ISO protein:decreased phosphorylation, decreased activity:T cell (rat) RGD PMID:9551931 RGD:2324866 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377 		JBrowse link
G Gas6 growth arrest specific 6 ISO RGD PMID:16374177 RGD:1579935 NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490 		JBrowse link
G Gata3 GATA binding protein 3 severity ISO RGD PMID:25403265 RGD:38455982 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Gch1 GTP cyclohydrolase 1 treatment ISO associated with Staphylococcal Infections RGD PMID:12441764 PMID:29428597 RGD:401700401, RGD:401717570 NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration ISO protein:increased expression:serum: RGD PMID:23073658 RGD:9685733 NCBI chr17:24,912,164...24,915,065
Ensembl chr17:24,912,161...24,915,503 		JBrowse link
G Ghr growth hormone receptor ISO RGD PMID:11126270 RGD:2307382 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974 		JBrowse link
G Ghrl ghrelin ISO mRNA,protein:decreased expression:aorta,heart, intestine, plasma: RGD PMID:15155262 RGD:12905047 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
G Ghsr growth hormone secretagogue receptor disease_progression ISO RGD PMID:15155262 RGD:12905047 NCBI chr 3:27,425,500...27,433,384
Ensembl chr 3:27,425,500...27,432,159 		JBrowse link
G Gja5 gap junction protein, alpha 5 ISO mRNA, protein:increased expression:aorta endothelium RGD PMID:15942348 RGD:7207815 NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732 		JBrowse link
G Gp1ba glycoprotein 1b, alpha polypeptide exacerbates IMP associated with thrombocytopenia RGD PMID:24150174 RGD:42722621 NCBI chr11:70,529,928...70,534,812
Ensembl chr11:70,529,948...70,532,862 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble treatment ISO RGD PMID:26814114 PMID:25243423 RGD:14975161, RGD:401717564 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) ISO protein:increased expression:lung (rat) RGD PMID:19837828 RGD:2325949 NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO protein: increased expression: neutrophils RGD PMID:16849637 RGD:5688378 NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO protein: increased expression: neutrophils RGD PMID:16849637 RGD:5688378 NCBI chr19:60,877,995...61,084,406
Ensembl chr19:60,878,187...61,084,406 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO protein:decreased phosphorylation,increased activity: : RGD PMID:20926980 RGD:10045370 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gsn gelsolin ISO protein:decreased expression:blood serum (human) RGD PMID:9142022 RGD:329333022 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 disease_progression ISO RGD PMID:23131280 RGD:7245480 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Hc hemolytic complement ISO protein:increased activation:plasma RGD PMID:18648551 PMID:14688199 RGD:5130170, RGD:1600599 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450 		JBrowse link
G Hdac4 histone deacetylase 4 ISO RGD PMID:23925573 RGD:9681446 NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421 		JBrowse link
G Hdac6 histone deacetylase 6 ISO RGD PMID:20538901 RGD:7364733 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128 		JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19265175 PMID:23146691 PMID:19623040 PMID:20936717 RGD:10402067, RGD:10402173 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) IEP protein: decreased expression RGD PMID:9603077 RGD:5688768 NCBI chr 8:56,747,587...56,774,081
Ensembl chr 8:56,747,620...56,774,078 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) ISO associated with burns;protein:decreased expression:skeletal muscle RGD PMID:16483253 PMID:23143056 RGD:1624233, RGD:10402864 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Htra2 HtrA serine peptidase 2 treatment ISO RGD PMID:23557966 RGD:10402934 NCBI chr 6:83,028,247...83,031,552
Ensembl chr 6:83,028,247...83,032,254 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA:increased expression:brain (rat) RGD PMID:20451670 RGD:4145409 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 treatment IMP RGD PMID:25114116 RGD:39938864 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
G Ifng interferon gamma treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9806674 PMID:27598601 PMID:28711488 RGD:14975121, RGD:14974250 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il10 interleukin 10 treatment ISO
IDA
IEP		 protein:increased expression:serum
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:11441115 PMID:19371254 PMID:27488951 PMID:28108420 PMID:24055021 RGD:2311053, RGD:14975262, RGD:14975261, RGD:7364867 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il12b interleukin 12b ISO protein:increased expression:peritoneal fluid, plasma RGD PMID:15776385 RGD:4888507 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il13 interleukin 13 IMP
ISO		 protein:decreased expression:ileum RGD PMID:10679115 PMID:21159497 RGD:4145654, RGD:8549643 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il16 interleukin 16 IEP associated with Shock, Hemorrhagic;protein:increased expression:lung RGD PMID:19641139 RGD:5024925 NCBI chr 7:83,292,027...83,395,479
Ensembl chr 7:83,292,033...83,394,934 		JBrowse link
G Il17a interleukin 17A ISO RGD PMID:15776385 RGD:4888507 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il17d interleukin 17D severity
treatment		 IDA
ISO
IMP		 protein:increased expression:blood serum (human) RGD PMID:31634237 PMID:31634237 PMID:31634237 RGD:40903064, RGD:40903064, RGD:40903064 NCBI chr14:57,762,197...57,780,623
Ensembl chr14:57,762,234...57,780,623 		JBrowse link
G Il1b interleukin 1 beta treatment ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:32062619 PMID:17529909 PMID:21429520 RGD:1626657, RGD:7175319 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity IMP RGD PMID:30001716 RGD:39938964 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
disease_progression
severity		 IEP
ISO		 mRNA, protein:increased expression:lung
associated with Premature Birth;DNA:polymorphism::
DNA:repeats: :
mRNA:increased expression:pituitary gland (rat)
protein:increased expression:serum (human)		 RGD PMID:20454520 PMID:22882323 PMID:11876758 PMID:10048466 PMID:8196140 More... RGD:4142852, RGD:12910846, RGD:11528543, RGD:7175061, RGD:6909139, RGD:6907358 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il22 interleukin 22 ISO protein:increased expression:plasma RGD PMID:19664145 RGD:5147412 NCBI chr10:118,040,456...118,045,952
Ensembl chr10:118,040,847...118,045,952 		JBrowse link
G Il27 interleukin 27 exacerbates
severity
disease_progression		 ISO
IEP
IMP		 protein:increased expression:blood (human)
mRNA:increased expression:blood, leukocyte (human)
associated with Herpesviridae Infections;protein:increased expression:blood serum, spleen (mouse)
DNA:SNP:promoter:-964A>G (rs153109) (human)		 RGD PMID:22965735 PMID:18227999 PMID:20493722 PMID:26767500 PMID:30268141 RGD:126790502, RGD:126790544, RGD:126790537, RGD:126790536, RGD:126790509 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Il33 interleukin 33 severity IMP
IEP
ISO		 protein:increased expression:plasma, peritoneal fluid:
protein:increased expression:plasma:
protein:increased expression:plasma,lung		 RGD PMID:29672927 PMID:29935165 PMID:29935165 PMID:25665614 PMID:29672927 RGD:39939028, RGD:40400895, RGD:40400895, RGD:40400739, RGD:39939028 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118 		JBrowse link
G Il4 interleukin 4 ISO protein:increased expression:plasma RGD PMID:25403265 RGD:38455982 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il6 interleukin 6 treatment ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; mRNA, protein:increased expression:liver, extracellular space (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:32062619 PMID:19079684 PMID:27598601 PMID:25317848 RGD:2307280, RGD:14975121, RGD:11062009 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 ISO RGD PMID:23073793 RGD:7495805 NCBI chr15:94,441,495...94,466,198
Ensembl chr15:94,441,524...94,479,696 		JBrowse link
G Irs1 insulin receptor substrate 1 ISO protein:decreased tyrosine phosphorylation, increased serine phosphorylation:gastrocnemius RGD PMID:19781177 RGD:6482862 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137 		JBrowse link
G Itga4 integrin alpha 4 ISO protein:increased expression:neutrophil RGD PMID:19011162 RGD:13593535 NCBI chr 2:79,084,767...79,163,458
Ensembl chr 2:79,085,770...79,163,467 		JBrowse link
G Itgam integrin alpha M exacerbates ISO protein:increased expression:neutrophil (rat) RGD PMID:9151199 RGD:329902068 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO RGD PMID:24228589 RGD:10411888 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 IMP RGD PMID:21799073 RGD:6892955 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO RGD PMID:22352684 RGD:7297048 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896 		JBrowse link
G Klrk1 killer cell lectin-like receptor subfamily K, member 1 susceptibility IMP associated with Gram-Negative Bacterial Infections RGD PMID:28087665 RGD:38676493 NCBI chr 6:129,587,286...129,600,863
Ensembl chr 6:129,587,286...129,600,827 		JBrowse link
G Lbp lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22167001 NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772 		JBrowse link
G Lcn2 lipocalin 2 exacerbates IMP RGD PMID:22786765 RGD:126781712 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Lep leptin ISO RGD PMID:18575315 RGD:5128818 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lipc lipase, hepatic ISO protein:decreased expression:diaphragm, heart, adipose tissue (rat) RGD PMID:2113037 RGD:2308797 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508 		JBrowse link
G Lta lymphotoxin A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22977509 NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327 		JBrowse link
G Ltf lactotransferrin ISO RGD PMID:23425819 RGD:7243861 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15489642 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15489642 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 treatment ISO RGD PMID:14662889 RGD:126928138 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO associated with Premature Birth;DNA:polymorphism:exon: RGD PMID:22882323 RGD:12910846 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Mfn2 mitofusin 2 ISO mRNA:decreased expression:liver (rat) RGD PMID:24720571 RGD:13204837 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:9892616 PMID:17585860 RGD:4891012 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mir143 microRNA 143 exacerbates ISO RGD PMID:30546393 RGD:155883166 NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329 		JBrowse link
G Mir146 microRNA 146 IEP miRNA:increased expression:myocardium, blood serum (mouse) RGD PMID:26048146 RGD:126925143 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Mir155 microRNA 155 ISO
IEP		 RGD PMID:27434558 PMID:29979224 RGD:21079467, RGD:21081538 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:plasma: RGD PMID:24680405 RGD:21408586 NCBI chr  X:95,286,423...95,286,532
Ensembl chr  X:95,286,423...95,286,532 		JBrowse link
G Mir483 microRNA 483 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32062619 NCBI chr 7:142,208,661...142,208,733
Ensembl chr 7:142,208,661...142,208,733 		JBrowse link
G Mir494 microRNA 494 ISO RNA:decreased expression:plasma RGD PMID:31002148 RGD:155900762 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836 		JBrowse link
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) ISO RGD PMID:23478082 RGD:8549749 NCBI chr 9:7,464,141...7,476,870
Ensembl chr 9:7,464,141...7,476,857 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) ISO RGD PMID:23478082 RGD:8549749 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO RGD PMID:23479197 RGD:8657110 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16003065 PMID:23479197 RGD:8657110 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mpo myeloperoxidase IMP RGD PMID:18424617 RGD:5130966 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G mt-Cytb cytochrome b, mitochondrial ISO protein:decreased expression:mitochondrion, skeletal muscle RGD PMID:6128308 RGD:2298978 NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288 		JBrowse link
G Mt1 metallothionein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17374846 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955 		JBrowse link
G Mt2 metallothionein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17374846 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:20577146 RGD:10041013 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Mylk myosin, light polypeptide kinase ISO RGD PMID:16399953 RGD:1581052 NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 ISO RGD PMID:22952679 RGD:13801198 NCBI chr19:44,537,010...44,543,881
Ensembl chr19:44,537,011...44,543,879 		JBrowse link
G Nefh neurofilament, heavy polypeptide severity ISO RGD PMID:30677080 RGD:27226881 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064 		JBrowse link
G Nefl neurofilament, light polypeptide disease_progression ISO RGD PMID:30677080 RGD:27226881 NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha treatment ISO RGD PMID:14662889 RGD:126928138 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility ISO DNA:missense mutations, frameshift mutation:cds:p.R702W, p.G908R, 3020_3021insC (human)
mRNA:increased expression:intestine mucosa (rat)		 RGD PMID:21460759 PMID:24059417 RGD:5508752, RGD:8547531 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal ISO RGD PMID:17191663 RGD:1642148 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible IDA
ISO		 associated with lung injury
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17138957 PMID:20035746 PMID:21184738 PMID:15665729 RGD:4891414, RGD:5147745 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO protein:increased expression:heart
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20035746 PMID:17999941 RGD:2292119 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nox1 NADPH oxidase 1 ameliorates IMP RGD PMID:22982050 RGD:329955362 NCBI chr  X:132,987,170...133,038,455
Ensembl chr  X:132,987,170...133,122,705 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IEP
ISO		 protein:decreased expression:alveolar macrophage RGD PMID:21057058 PMID:21787473 RGD:4892317, RGD:7174711 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Otc ornithine transcarbamylase ISO mRNA:decreased expression:liver (rat) RGD PMID:10353541 RGD:4144069 NCBI chr  X:10,118,584...10,187,275
Ensembl chr  X:10,118,544...10,187,263 		JBrowse link
G Pdcd1 programmed cell death 1 disease_progression ISO
IMP		 protein:increased expression:T cell
protein:increased expression:B cell,CD4T cell		 RGD PMID:30595665 PMID:27156867 PMID:29702526 PMID:29661225 PMID:19332785 RGD:40818235, RGD:41412183, RGD:40822808, RGD:40818424, RGD:40818273 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 ISO protein:increased expression:CD27B cell RGD PMID:29661225 RGD:40818424 NCBI chr19:29,388,319...29,450,327
Ensembl chr19:29,388,319...29,448,561 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 disease_progression IEP protein:increased expression:myeloid suppressor cell (mouse) RGD PMID:22451518 RGD:6771205 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Pgf placental growth factor IEP protein:increased expression:plasma RGD PMID:16702604 RGD:6483601 NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IMP RGD PMID:20508212 RGD:6482683 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) ISO protein:increased activity:liver RGD PMID:9879654 RGD:1642481 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041 		JBrowse link
G Plat plasminogen activator, tissue treatment ISO RGD PMID:12000738 RGD:1598921 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plau plasminogen activator, urokinase disease_progression ISO Pneumonia associated sepsis RGD PMID:21219633 RGD:4891938 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO protein:increased expression:plasma RGD PMID:22550400 RGD:6483789 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha severity IAGP DNA:knockout::associated with more severe disease RGD PMID:22089192 RGD:5562037 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha IEP mRNA:decreased expression:skeletal muscle RGD PMID:20647557 RGD:6484531 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta IEP mRNA:decreased expression:skeletal muscle RGD PMID:20647557 RGD:6484531 NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502 		JBrowse link
G Ppia peptidylprolyl isomerase A treatment IMP RGD PMID:29680745 RGD:150429626 NCBI chr11:6,365,867...6,369,817
Ensembl chr11:6,365,443...6,369,817 		JBrowse link
G Prkcq protein kinase C, theta ISO protein:decreased expression:lymphocyte RGD PMID:11735277 RGD:1625613 NCBI chr 2:11,176,922...11,306,033
Ensembl chr 2:11,176,919...11,306,033 		JBrowse link
G Proc protein C treatment
disease_progression		 ISO CTD Direct Evidence: therapeutic
mRNA, protein:decreased expression:liver, plasma		 CTD
RGD		 PMID:11820775 PMID:17556722 PMID:22940033 PMID:15241104 RGD:11100029, RGD:11250412 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Pvt1 Pvt1 oncogene ISO RNA:increased expression:myocardium RGD PMID:30546393 RGD:155883166 NCBI chr15:61,909,835...62,132,064
Ensembl chr15:61,888,639...62,249,945 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO mRNA:increased expression:blood serum (human) RGD PMID:33174038 RGD:152998912 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO protein:increased expression:nucleus, lung RGD PMID:17626913 RGD:2298853 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Retn resistin ISO protein:increased expression:serum RGD PMID:19545363 RGD:7207151 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 no_association
ameliorates		 IMP
IGI		 RGD PMID:23835476 PMID:32152555 PMID:22195746 RGD:127229908, RGD:127229919, RGD:127229909 NCBI chr14:56,022,452...56,026,314
Ensembl chr14:56,022,452...56,026,322 		JBrowse link
G Rpl4 ribosomal protein L4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27978524 NCBI chr 9:64,080,159...64,085,805
Ensembl chr 9:64,080,657...64,085,948 		JBrowse link
G Rpl9 ribosomal protein L9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27978524 NCBI chr 5:65,545,707...65,548,774
Ensembl chr 5:65,545,707...65,548,787 		JBrowse link
G Rxra retinoid X receptor alpha ISO protein:altered localization:liver
protein:decreased expression:liver		 RGD PMID:19008781 PMID:17483744 RGD:2317466, RGD:1643106 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G Ryr1 ryanodine receptor 1, skeletal muscle ISO mRNA:increased expression:fast muscle tissue
protein:decreased expression:diaphragmaticus muscle		 RGD PMID:18520643 PMID:28044347 RGD:329849107, RGD:329849111 NCBI chr 7:28,702,765...28,824,599
Ensembl chr 7:28,702,769...28,824,604 		JBrowse link
G S100b S100 protein, beta polypeptide, neural ISO RGD PMID:19809934 RGD:5508796 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993 		JBrowse link
G Sell selectin, lymphocyte ISO RGD PMID:16026013 PMID:15677732 RGD:5685706, RGD:5686285 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750 		JBrowse link
G Selp selectin, platelet IEP protein:increased expression:multiple RGD PMID:20690979 RGD:6478679 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 treatment ISO associated with Pneumonia; protein:increased expression:plasma RGD PMID:19753144 PMID:12000738 RGD:4144830, RGD:1598921 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 ISO RGD PMID:20338592 RGD:9999218 NCBI chr15:96,585,267...96,597,609
Ensembl chr15:96,585,273...96,597,611 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 ISO mRNA:decreased expression:liver RGD PMID:10500057 RGD:631887 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO protein:increased expression:gastrocnemius
mRNA:increased expression:liver		 RGD PMID:12644450 PMID:11312157 RGD:2298924, RGD:634751 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO protein:increased expression:gastrocnemius RGD PMID:12644450 RGD:2298924 NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO protein:increased expression:gastrocnemius
mRNA:increased expression:liver		 RGD PMID:12644450 PMID:11312157 RGD:2298924, RGD:634751 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873 		JBrowse link
G Sod1 superoxide dismutase 1, soluble ISO RGD PMID:26266917 RGD:11035300 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO mRNA, protein:increased expression:lung RGD PMID:26266917 RGD:11035300 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sod3 superoxide dismutase 3, extracellular ISO RGD PMID:26266917 RGD:11035300 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO protein:increased activity:liver, lung, small intestine RGD PMID:17067487 RGD:2291905 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment ISO RGD PMID:24228589 RGD:10411888 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 IMP RGD PMID:11257135 RGD:7207876 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity IMP RGD PMID:11257135 RGD:7207876 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Tbx21 T-box 21 severity ISO RGD PMID:25403265 RGD:38455982 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
G Tfpi tissue factor pathway inhibitor ISO protein:decreased activity:plasma: RGD PMID:15497025 RGD:2313648 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16003065 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfbi transforming growth factor, beta induced ISO CTD Direct Evidence: marker/mechanism CTD PMID:27887929 NCBI chr13:56,757,399...56,787,172
Ensembl chr13:56,757,336...56,787,375 		JBrowse link
G Thbd thrombomodulin ISO RGD PMID:17577447 RGD:2312462 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Tlr2 toll-like receptor 2 ISO associated with Burns;mRNA:increased expression:liver, lung, kidney
associated with Liver Diseases;mRNA:increased expression:liver		 RGD PMID:14604479 PMID:12831613 PMID:19489280 RGD:2312732, RGD:1302750, RGD:2312497 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 ISO associated with Sepsis;mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20624996 PMID:19489280 PMID:14604479 RGD:2312497, RGD:2312732 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tlr6 toll-like receptor 6 ISO mRNA:increased expression:plasma RGD PMID:31002148 RGD:155900762 NCBI chr 5:65,109,373...65,128,387
Ensembl chr 5:65,109,374...65,117,440 		JBrowse link
G Tnf tumor necrosis factor treatment ISO
IDA		 mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:8741040 PMID:9806674 PMID:15489642 PMID:19695174 PMID:27488951 More... RGD:4144094, RGD:14975262, RGD:7364867, RGD:5147745 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Top2a topoisomerase (DNA) II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27978524 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
G Tpp2 tripeptidyl peptidase II ISO mRNA, protein:increased expression, increased activity:extensor digitorum longus (rat) RGD PMID:12147224 RGD:634435 NCBI chr 1:43,973,130...44,042,160
Ensembl chr 1:43,972,807...44,042,160 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 disease_progression
treatment		 ISO mRNA:decreased expression:polymorph nuclear cell: RGD PMID:22809118 PMID:22147417 PMID:22996209 RGD:126925981, RGD:127284847, RGD:126925987 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Tslp thymic stromal lymphopoietin treatment
disease_progression		 IMP
IEP		 protein:increased expression:peritoneum, plasma (mouse) RGD PMID:24990542 PMID:26934097 RGD:38549375, RGD:38596335 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850 		JBrowse link
G Xdh xanthine dehydrogenase treatment ISO RGD PMID:19751566 RGD:7247648 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
G Xiap X-linked inhibitor of apoptosis ISO ClinVar Annotator: match by term: Sepsis ClinVar PMID:17080092 PMID:21119115 PMID:25666262 PMID:25741868 PMID:27747465 More... NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533 		JBrowse link
Bacteremia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement component 3 ISO associated with Experimental Liver Cirrhosis; protein:decreased expression:serum RGD PMID:11349015 RGD:408395143 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO associated with Febrile Neutropenia;protein:increased expression:serum (human) RGD PMID:22584776 RGD:11528568 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta IEP associated with alcohol use disorder;mRNA:increased expression:bone marrow (mouse) RGD PMID:28784931 RGD:40903040 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Cfh complement component factor h ISO associated with Meningococcal Infections; RGD PMID:22104107 RGD:7364945 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502 		JBrowse link
G Cish cytokine inducible SH2-containing protein susceptibility ISO ClinVar Annotator: match by term: Bacteremia, susceptibility to, 2
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:20484391 NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983 		JBrowse link
G Cpb2 carboxypeptidase B2 ISO protein:decreased activity:plasma RGD PMID:17911187 RGD:2313646 NCBI chr14:75,479,727...75,520,995
Ensembl chr14:75,479,727...75,520,995 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:serum: RGD PMID:18443549 RGD:9491402 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) treatment IDA RGD PMID:2192004 RGD:10449532 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III ISO associated with Pneumonia;DNA:SNP: :p.H131R (rs1801274) (human) RGD PMID:21317643 RGD:5147986 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase severity ISO RGD PMID:11565076 RGD:5508478 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP mRNA:increased expression:lung,thymus,spleen: RGD PMID:24891762 RGD:11354979 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Il17a interleukin 17A ISO associated with Respiratory Distress Syndrome, Adult; protein:increased expression:serum RGD PMID:21062445 RGD:5128683 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il27 interleukin 27 ISO protein:increased expression:blood serum (human) RGD PMID:26514771 RGD:126790515 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Itih4 inter alpha-trypsin inhibitor, heavy chain 4 IEP protein:increased expression:liver, serum RGD PMID:33348064 RGD:40907057 NCBI chr14:30,608,433...30,623,943
Ensembl chr14:30,608,433...30,624,310 		JBrowse link
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 ISO ClinVar Annotator: match by term: Bacteremia, susceptibility to, 2 ClinVar PMID:20484391 NCBI chr 9:107,132,125...107,167,082
Ensembl chr 9:107,132,126...107,167,076 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 treatment ISO associated with Multiple Myeloma:DNA:polymorphism:exon: RGD PMID:16953214 RGD:11530047 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 severity ISO associated with Staphylococcal Infections; RGD PMID:24086711 RGD:13204726 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plaur plasminogen activator, urokinase receptor severity ISO RGD PMID:21332843 RGD:6483799 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 treatment ISO RGD PMID:2679067 RGD:11035251 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial IEP mRNA:increased expression:liver: RGD PMID:24253037 RGD:26923958 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Bacteremia, susceptibility to, 1		 CTD
ClinVar
OMIM		 PMID:16991088 PMID:17322885 PMID:18305471 PMID:25741868 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587 		JBrowse link
G Tlr4 toll-like receptor 4 susceptibility ISO DNA:polymorphisms:cds:p.D299G, T399I (human) RGD PMID:18180796 RGD:4144194 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
bacterial sepsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem1 triggering receptor expressed on myeloid cells 1 treatment
ameliorates
exacerbates		 ISO
IMP		 associated with bacterial pneumonia RGD PMID:21507332 PMID:16960786 PMID:17230441 RGD:126925982, RGD:127229902, RGD:126928125 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
Candidemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 antigen ameliorates IMP associated with endotoxemia RGD PMID:32154791 RGD:127345119 NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748 		JBrowse link
G Ephb2 Eph receptor B2 exacerbates IMP RGD PMID:33685996 RGD:127229905 NCBI chr 4:136,374,850...136,563,637
Ensembl chr 4:136,374,850...136,563,299 		JBrowse link
cerebral malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 susceptibility ISO DNA:SNP:intron 1: C>T RGD PMID:20117248 RGD:40818420 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Aqp4 aquaporin 4 disease_progression IEP protein:increased expression:astrocyte: RGD PMID:21904632 RGD:8698661 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039 		JBrowse link
G Cast calpastatin IEP protein:increased express:brain RGD PMID:16236382 RGD:5509817 NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929 		JBrowse link
G Cd36 CD36 molecule IMP RGD PMID:17367535 RGD:6893527 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Clec12a C-type lectin domain family 12, member a ameliorates IMP RGD PMID:31269448 RGD:41412201 NCBI chr 6:129,327,207...129,342,266
Ensembl chr 6:129,319,654...129,342,266 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 treatment IMP RGD PMID:25682948 RGD:40400741 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575 		JBrowse link
G Il33 interleukin 33 treatment IDA
IEP		 protein:increased expression:brain RGD PMID:25659095 PMID:25682948 RGD:39938955, RGD:40400741 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118 		JBrowse link
G Jak3 Janus kinase 3 IMP RGD PMID:22363534 RGD:11531103 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Lta lymphotoxin A IMP RGD PMID:12021316 RGD:10449455 NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327 		JBrowse link
G Nrg1 neuregulin 1 treatment IEP
ISO		 mRNA, protein:increased expression:cerebral cortex (mouse)
human protein in a mouse model		 RGD PMID:29636063 PMID:24433482 RGD:39456084, RGD:39456102 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IMP RGD PMID:25775137 RGD:38599200 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658 		JBrowse link
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit IEP mRNA:decreased expression:brain (mouse) RGD PMID:29107705 RGD:39456137 NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b IMP RGD PMID:12228317 RGD:5131158 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
Endotoxemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 ISO RGD PMID:9828229 RGD:1598596 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958 		JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO mRNA:decreased expression:liver (rat) RGD PMID:26977098 RGD:11041000 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20300455 PMID:9828229 RGD:1598596 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO RGD PMID:16572733 RGD:1598611 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc8 ATP-binding cassette, sub-family C member 8 ISO RGD PMID:17285300 RGD:2301914 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Ace angiotensin I converting enzyme ISO associated with Hemorrhage;protein:decreased activity:plasma (rat) RGD PMID:3028670 RGD:8142370 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ache acetylcholinesterase ISO RGD PMID:17657467 RGD:5688055 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 ISO RGD PMID:11680626 RGD:1598729 NCBI chr 2:113,877,763...113,883,356
Ensembl chr 2:113,877,763...113,884,029 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO protein:increased expression:plasma, spleen RGD PMID:23025351 RGD:9681752 NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with Obesity RGD PMID:23838384 RGD:8695926 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adipor2 adiponectin receptor 2 severity ISO associated with obesity;mRNA:decreased expression:liver (rat) RGD PMID:23838384 RGD:8695926 NCBI chr 6:119,330,111...119,394,489
Ensembl chr 6:119,330,111...119,394,665 		JBrowse link
G Adra2a adrenergic receptor, alpha 2a onset ISO mRNA:increased expression:spleen RGD PMID:20302880 RGD:6480487 NCBI chr19:54,033,690...54,037,413
Ensembl chr19:54,032,582...54,037,413 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO protein:increased expression:kidney RGD PMID:16725227 RGD:6903849 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO protein:decreased expression:kidney RGD PMID:16725227 RGD:6903849 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Ahr aryl-hydrocarbon receptor severity IMP RGD PMID:24930766 RGD:39939032 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Akp3 alkaline phosphatase 3, intestine, not Mn requiring IMP RGD PMID:23569246 RGD:14349049 NCBI chr 1:87,052,676...87,056,450
Ensembl chr 1:87,052,695...87,055,634 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 ISO RGD PMID:22824368 RGD:38676479 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Aldoa aldolase A, fructose-bisphosphate ISO RGD PMID:16930621 RGD:1599054 NCBI chr 7:126,394,406...126,399,537
Ensembl chr 7:126,394,406...126,399,923 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15328337 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Apoa1 apolipoprotein A-I treatment ISO RGD PMID:18593575 PMID:23227448 RGD:7241573, RGD:7241868 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Apob apolipoprotein B ISO RGD PMID:16719989 RGD:1599165 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Apoe apolipoprotein E ISO rat model treated with human protein RGD PMID:9153287 RGD:6904216 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Asl argininosuccinate lyase ISO RGD PMID:10652239 RGD:1599265 NCBI chr 5:130,040,099...130,053,222
Ensembl chr 5:130,040,099...130,058,088 		JBrowse link
G Ass1 argininosuccinate synthetase 1 ISO RGD PMID:10652239 RGD:1599265 NCBI chr 2:31,360,282...31,410,682
Ensembl chr 2:31,360,219...31,410,684 		JBrowse link
G Atf2 activating transcription factor 2 treatment ISO protein:increased expression, increased activity:small intestine mucosa RGD PMID:21641970 PMID:24312512 RGD:5135029, RGD:10047418 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569 		JBrowse link
G Bax BCL2-associated X protein ISO mRNA:increased expression:diaphragm RGD PMID:23940949 RGD:10054120 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bche butyrylcholinesterase ISO RGD PMID:17657467 RGD:5688055 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO mRNA:decreased expression:diaphragm RGD PMID:23940949 RGD:10054120 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G C5ar1 complement component 5a receptor 1 ISO mRNA:increased expression:lung RGD PMID:9272704 RGD:70679 NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465 		JBrowse link
G Casp1 caspase 1 ISO RGD PMID:17384935 RGD:2315892 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp3 caspase 3 ISO mRNA:increased expression:diaphragm RGD PMID:23940949 RGD:10054120 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp7 caspase 7 IMP RGD PMID:19168786 RGD:5684539 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:23214195 RGD:10400903 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cbs cystathionine beta-synthase severity IMP
IEP
ISO		 Protein:increased expression:spleen, lung (mouse)
mRNA:increased expression:liver (rat)		 RGD PMID:27748832 PMID:27748832 PMID:24702258 PMID:16100527 RGD:40903019, RGD:40903019, RGD:40903035, RGD:40903049 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO protein:increased expression:plasma RGD PMID:19060786 RGD:2307004 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased expression:plasma RGD PMID:16215387 RGD:2307171 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 IMP RGD PMID:17016504 RGD:5688178 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729 		JBrowse link
G Cd14 CD14 antigen ISO protein:increased expression:liver, endothelial cell of sinusoid RGD PMID:12046090 RGD:724637 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd40 CD40 antigen IDA protein:decreased nitrosylation:macrophage RGD PMID:20473113 RGD:5490974 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta treatment ISO
IDA		 RGD PMID:15192048 PMID:14659593 RGD:1625687, RGD:40903034 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Cps1 carbamoyl-phosphate synthetase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr 1:67,151,294...67,270,426
Ensembl chr 1:67,162,185...67,270,418 		JBrowse link
G Cs citrate synthase ISO protein:increased expression:gastrocnemius RGD PMID:25674200 RGD:329337350 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) treatment ISO RGD PMID:9514298 RGD:11039535 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:atrium endocardium RGD PMID:19282612 RGD:4891965 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 IEP mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Edn1 endothelin 1 ISO mRNA, protein:increased expression:liver (rat) RGD PMID:11206318 RGD:8662297 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Ep300 E1A binding protein p300 ISO associated with Kidney Reperfusion Injury; protein:altered localization:kidney (rat) RGD PMID:23936185 RGD:7257563 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic IMP RGD PMID:19154430 RGD:5688360 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:23214195 RGD:10400903 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO RGD PMID:11092686 RGD:7394782 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606 		JBrowse link
G F2 coagulation factor II treatment
severity		 ISO associated with liver cirrhosis;protein:increased expression:blood plasma (human)
associated with liver cirrhosis;protein:increased expression:plasma (human)		 RGD PMID:21396682 PMID:10604885 PMID:7615203 PMID:10887118 PMID:9863491 More... RGD:5147765, RGD:40818436, RGD:14974253, RGD:40818427, RGD:14401592, RGD:10449434, RGD:6893482, RGD:5147779 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G F3 coagulation factor III treatment ISO
IMP		 associated with Protein C Deficiency RGD PMID:21396682 PMID:20858853 PMID:8956768 RGD:5147765, RGD:11341685, RGD:11340208 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G F5 coagulation factor V ISO RGD PMID:11092686 RGD:7394782 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846 		JBrowse link
G F7 coagulation factor VII treatment ISO
IMP		 RGD PMID:11092686 PMID:16378835 RGD:7394782, RGD:11041650 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G F8 coagulation factor VIII ISO RGD PMID:11092686 RGD:7394782 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221 		JBrowse link
G Fas Fas cell surface death receptor ISO mRNA, protein:increased expression:spleen (rat) RGD PMID:20428798 RGD:8662930 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fga fibrinogen alpha chain treatment ISO RGD PMID:19295478 RGD:11040925 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934 		JBrowse link
G Foxp3 forkhead box P3 ISO protein:increased expression:intestinal mucosa RGD PMID:19998507 RGD:38455980 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gch1 GTP cyclohydrolase 1 treatment ISO mRNA:increased expression:lung
associated with liver cirrhosis		 RGD PMID:9388472 PMID:16845913 PMID:14647062 RGD:329961576, RGD:401793756, RGD:401700399 NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration ISO RGD PMID:23073658 RGD:9685733 NCBI chr17:24,912,164...24,915,065
Ensembl chr17:24,912,161...24,915,503 		JBrowse link
G Ghr growth hormone receptor ISO mRNA:decreased expression:liver RGD PMID:12654216 PMID:12217886 RGD:2307380, RGD:625688 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble treatment ISO RGD PMID:25514429 RGD:401717525 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gsr glutathione reductase treatment ISO RGD PMID:25469663 RGD:10401928 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Hmgb1 high mobility group box 1 ISO protein:increased expression:heart, serum RGD PMID:18503231 RGD:10402065 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:21396999 RGD:10755715 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hsf1 heat shock factor 1 treatment ISO RGD PMID:25571843 RGD:10402404 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113 		JBrowse link
G Hspa9 heat shock protein 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) ISO mRNA, protein:increased expression:medulla oblongata
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16741687 PMID:16675490 RGD:1624232 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:lung (rat) RGD PMID:19776691 RGD:4145502 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IMP RGD PMID:24930766 PMID:28077574 RGD:39939032, RGD:39939117 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IMP RGD PMID:24930766 RGD:39939032 NCBI chr 8:25,021,908...25,066,430
Ensembl chr 8:25,021,908...25,066,349 		JBrowse link
G Ifng interferon gamma ISO protein:increased expression:serum: RGD PMID:9195172 RGD:10755747 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO mRNA, protein:decreased expression:liver, serum RGD PMID:18492809 PMID:12217886 RGD:10402757, RGD:625688 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit ISO RGD PMID:12217886 RGD:625688 NCBI chr17:25,096,818...25,100,985
Ensembl chr17:25,084,971...25,100,984 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 ISO RGD PMID:12217886 RGD:625688 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO mRNA, protein:decreased expression:liver, serum RGD PMID:18492809 RGD:10402757 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 ISO RGD PMID:12217886 RGD:625688 NCBI chr 1:72,897,224...72,914,024
Ensembl chr 1:72,897,091...72,914,043 		JBrowse link
G Il10 interleukin 10 treatment IEP RGD PMID:28664613 PMID:27943364 RGD:14975137, RGD:14975170 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il13 interleukin 13 treatment ISO RGD PMID:10674721 RGD:8549626 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il1a interleukin 1 alpha IEP
ISO		 protein:increased expression:plasma RGD PMID:9636192 PMID:22426124 RGD:6907109, RGD:7794786 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:plasma RGD PMID:17201737 RGD:1626625 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO mRNA:increased expression:lung, spleen, liver (rat) RGD PMID:1385928 PMID:8855299 RGD:8551846, RGD:11522760 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il6 interleukin 6 ISO associated with Diabetes Mellitus, Experimental; Protein:increased expression:extracellular space (rat)
protein:increased expression:serum (rat)		 RGD PMID:19449282 PMID:22227956 PMID:21396682 RGD:2307179, RGD:6893482, RGD:5147765 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA, protein:increased expression:blood (human) RGD PMID:17982103 RGD:36049802 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Irs1 insulin receptor substrate 1 IDA protein:increased tyrosine nitration, decreased tyrosine phosphorylation:skeletal muscle RGD PMID:21206533 RGD:6483008 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137 		JBrowse link
G Itga2b integrin alpha 2b ISO RGD PMID:15280099 RGD:2316360 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948 		JBrowse link
G Itgb3 integrin beta 3 ISO RGD PMID:15280099 RGD:2316360 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 IMP RGD PMID:22609006 RGD:6892951 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G Lbp lipopolysaccharide binding protein treatment ISO
IMP		 mRNA:increased expression:hepatocyte RGD PMID:8418776 PMID:8593028 PMID:16307218 RGD:9685191, RGD:9685196, RGD:9685193 NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772 		JBrowse link
G Lcn2 lipocalin 2 IEP mRNA:increased expression:brain,liver RGD PMID:21943033 RGD:126779582 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Map2 microtubule-associated protein 2 IEP mRNA, protein:decreased expression:neuron RGD PMID:21421895 RGD:6483086 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 treatment ISO protein:increased activity:small intestine mucosa RGD PMID:21641970 PMID:24312512 RGD:5135029, RGD:10047418 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO protein:increased phophorylation:hippocampus (rat) RGD PMID:12207162 RGD:150340687 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mc4r melanocortin 4 receptor ISO mRNA:increased expression:paraventricular nucleus (rat) RGD PMID:21343543 RGD:6484214 NCBI chr18:66,990,776...66,993,558
Ensembl chr18:66,990,775...66,993,577 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) ISO protein:increased expression:plasma RGD PMID:16601957 RGD:1641983 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mir146 microRNA 146 treatment IEP miRNA:increased expression:spleen (mouse) RGD PMID:30867482 RGD:34888227 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Mir155 microRNA 155 treatment IEP associated with familial hyperlipidemia RGD PMID:28970282 PMID:28264607 PMID:29079998 PMID:29979224 RGD:21079445, RGD:24922204, RGD:21081539, RGD:21081538 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Mme membrane metallo endopeptidase severity ISO RGD PMID:11078421 RGD:13801040 NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:17083784 RGD:2290426 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mt2 metallothionein 2 ISO mRNA:increased expression:liver (rat) RGD PMID:22100509 RGD:6483852 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Mt3 metallothionein 3 ISO RGD PMID:12135776 RGD:10412330 NCBI chr 8:94,879,235...94,880,776
Ensembl chr 8:94,879,235...94,880,774 		JBrowse link
G Muc2 mucin 2 ISO RGD PMID:19099858 RGD:7349370 NCBI chr 7:141,276,583...141,308,428
Ensembl chr 7:141,276,583...141,308,430 		JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha ISO RGD PMID:7874842 RGD:12792976 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384 		JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta ISO RGD PMID:7874842 RGD:12792976 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO RGD PMID:26646455 RGD:42722616 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha exacerbates
treatment		 IMP
IEP		 RGD PMID:19098124 PMID:10229101 RGD:126908017, RGD:126928139 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO mRNA, protein:increased expression:intestine
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12620498 PMID:16787348 PMID:20519137 RGD:4891470, RGD:5147779 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO protein:increased expression:aorta (rat) RGD PMID:10462376 RGD:7794732 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Npy neuropeptide Y treatment ISO RGD PMID:15342191 RGD:1580787 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO RGD PMID:15640646 RGD:4892561 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Otc ornithine transcarbamylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr  X:10,118,584...10,187,275
Ensembl chr  X:10,118,544...10,187,263 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic ISO RGD PMID:19268478 PMID:12217886 RGD:10427879, RGD:625688 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) ISO mRNA,protein:decreased expression,decreased activity:liver: RGD PMID:19268478 RGD:10427879 NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 ISO RGD PMID:16337011 RGD:6483567 NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 ISO RGD PMID:16337011 RGD:6483567 NCBI chr 2:143,388,053...143,658,204
Ensembl chr 2:143,388,076...143,658,205 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 IMP RGD PMID:22119535 RGD:6771174 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Pf4 platelet factor 4 treatment ISO RGD PMID:20601223 RGD:329901905 NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242 		JBrowse link
G Pgf placental growth factor IEP protein:increased expression:multiple RGD PMID:16702604 RGD:6483601 NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564 		JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) ISO protein:increased expression: : RGD PMID:10748027 RGD:7248791 NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092 		JBrowse link
G Plat plasminogen activator, tissue treatment ISO RGD PMID:9091588 RGD:11541073 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO protein:increased expression:small intestine mucosa RGD PMID:21641970 RGD:5135029 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit IEP mRNA:decreased expression:epididymal fat pad RGD PMID:20421294 RGD:6484543 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IEP protein:increased expression:liver, mitochondrion (mouse) RGD PMID:28615325 RGD:13432559 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Proc protein C treatment ISO RGD PMID:18205901 PMID:23170801 RGD:11100030, RGD:11100034 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Ptafr platelet-activating factor receptor treatment ISO RGD PMID:2178565 RGD:10041063 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994 		JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) ISO protein:increased expression:paraventricular hypothalamic nucleus parvicellular division (rat) RGD PMID:11058222 RGD:10043329 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668 		JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase treatment ISO RGD PMID:11076704 RGD:401960076 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:21641970 RGD:5135029 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Ren1 renin 1 structural IEP
ISO		 protein:increased activity:blood plasma (mouse)
protein:increased activity:blood plasma (rat)		 RGD PMID:30027346 PMID:16512638 RGD:125097481, RGD:125097499 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 treatment ISO RGD PMID:16457847 PMID:21396682 PMID:20519137 PMID:15995859 RGD:1599326, RGD:5147765, RGD:5147779, RGD:1599332 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 treatment ISO RGD PMID:21396682 PMID:25396762 RGD:5147765, RGD:10449434 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 ISO protein:increased expression:plasma (human) RGD PMID:12386642 RGD:36174005 NCBI chr11:75,300,855...75,313,449
Ensembl chr11:75,300,595...75,313,527 		JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 treatment ISO RGD PMID:18652771 RGD:8661643 NCBI chr 2:84,595,704...84,605,748
Ensembl chr 2:84,595,731...84,605,788 		JBrowse link
G Slc18a3 solute carrier family 18 (vesicular monoamine), member 3 ISO protein:decreased expression:parietal cortex RGD PMID:17306796 RGD:5686693 NCBI chr14:32,184,394...32,186,807
Ensembl chr14:32,184,395...32,186,807 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 treatment ISO RGD PMID:18313662 RGD:7243881 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 treatment ISO RGD PMID:18313662 RGD:7243881 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Slc38a3 solute carrier family 38, member 3 ISO RGD PMID:20036385 RGD:9999227 NCBI chr 9:107,528,353...107,546,167
Ensembl chr 9:107,527,833...107,546,729 		JBrowse link
G Slc38a5 solute carrier family 38, member 5 ISO RGD PMID:20036385 RGD:9999227 NCBI chr  X:8,137,620...8,146,418
Ensembl chr  X:8,137,372...8,146,418 		JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 ISO RGD PMID:26337286 RGD:151361133 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor ISO RGD PMID:25466948 RGD:9999425 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 IEP mRNA:increased expression:liver, skeletal muscle RGD PMID:15169905 RGD:2298923 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 IEP
ISO		 mRNA:increased expression:liver, skeletal muscle RGD PMID:15169905 PMID:12217886 RGD:2298923, RGD:625688 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein ISO mRNA, protein:decreased expression:kidney RGD PMID:10703670 RGD:2300026 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B ISO protein:decreased tyrosine phosphorylation:liver RGD PMID:17327369 RGD:1601383 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550 		JBrowse link
G Tbxa2r thromboxane A2 receptor ISO RGD PMID:15647606 PMID:2580129 RGD:1601450, RGD:11059531 NCBI chr10:81,164,102...81,171,008
Ensembl chr10:81,164,565...81,171,006 		JBrowse link
G Tbxas1 thromboxane A synthase 1, platelet ISO RGD PMID:15647606 RGD:1601450 NCBI chr 6:38,817,897...39,061,524
Ensembl chr 6:38,852,338...39,061,519 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase severity IMP RGD PMID:24930766 RGD:39939032 NCBI chr 3:81,865,719...81,883,035
Ensembl chr 3:81,864,397...81,883,509 		JBrowse link
G Tfpi tissue factor pathway inhibitor treatment ISO RGD PMID:17537762 RGD:11062086 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119 		JBrowse link
G Thbd thrombomodulin ISO
IEP		 mRNA:decreased expression:endothelial cell RGD PMID:12611420 PMID:20348393 PMID:19487933 RGD:1601652, RGD:5685037, RGD:5684988 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Timp3 tissue inhibitor of metalloproteinase 3 ISO RGD PMID:17083784 RGD:2290426 NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370 		JBrowse link
G Tlr2 toll-like receptor 2 treatment ISO RGD PMID:22172266 RGD:7241094 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 treatment
disease_progression		 ISO
IEP
IMP		 mRNA:increased expression:liver: RGD PMID:22172266 PMID:23977376 PMID:23977376 RGD:7241094, RGD:14697731, RGD:14697731 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor treatment ISO
IEP		 protein:increased expression:plasma
XCO:0000822 JTE-607
associated with liver cirrhosis
protein:increased expression:plasma (rat)		 RGD PMID:17324147 PMID:10493164 PMID:15242491 PMID:18078960 PMID:8283134 More... RGD:4891465, RGD:40903016, RGD:38501090, RGD:15023464, RGD:14995443, RGD:14995427, RGD:5147765, RGD:5147779 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment IEP
ISO		 RGD PMID:21507332 PMID:15585833 RGD:126925982, RGD:126928122 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO mRNA:increased expression:brain: RGD PMID:20061033 RGD:7240511 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337 		JBrowse link
G Vwf Von Willebrand factor ISO protein:increased expression:endothelial cell: RGD PMID:2650559 RGD:11079230 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
endotoxin shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 treatment ISO RGD PMID:8602831 RGD:329961578 NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870 		JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A treatment ISO RGD PMID:19318092 RGD:401901206 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934 		JBrowse link
Fungemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 antigen treatment IMP RGD PMID:23663657 RGD:40818234 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Pdcd1 programmed cell death 1 treatment IMP
IEP		 protein:increased expression:CD4 Tcell, CD8 Tcell: RGD PMID:23663657 PMID:23663657 RGD:40818234, RGD:40818234 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A treatment
susceptibility		 ISO DNA:SNP: :c3435C>T(human)
DNA:hypermethylation:promoter
DNA:SNPs,haplotype: :rs2032582, rs1128503 (human)
DNA:haplotype: :1236C>T, 2677G>T,3435C>T (human) 		RGD PMID:28934955 PMID:19331170 PMID:28422980 PMID:17015054 RGD:39456120, RGD:39457680, RGD:39457679, RGD:39456123 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Ace angiotensin I converting enzyme severity IMP RGD PMID:31234939 RGD:39939120 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ackr1 atypical chemokine receptor 1 (Duffy blood group) ISO ClinVar Annotator: match by term: Plasmodium vivax, resistance to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:7663520 PMID:8547665 PMID:8651934 PMID:10570183 PMID:10791881 More... NCBI chr 1:173,159,457...173,161,079
Ensembl chr 1:173,159,453...173,161,317 		JBrowse link
G Aicda activation-induced cytidine deaminase IEP protein:increased expression: B cell RGD PMID:27980783 RGD:30310233 NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139 		JBrowse link
G Ank1 ankyrin 1, erythroid IAGP OMIM:609148 | OMIM:611162 MouseDO NCBI chr 8:23,464,852...23,640,517
Ensembl chr 8:23,464,860...23,640,513 		JBrowse link
G Apoe apolipoprotein E ISO DNA:missense mutations:cds:p.C112R, p.C158R (human) RGD PMID:24116184 RGD:11039486 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Aqp4 aquaporin 4 IAGP OMIM:609148 | OMIM:611162 MouseDO NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039 		JBrowse link
G Cbs cystathionine beta-synthase susceptibility ISO DNA:insertion:cds: (844ins68) (human) RGD PMID:27198213 RGD:40903062 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212 		JBrowse link
G Cd163 CD163 antigen exacerbates
severity		 ISO protein:increased expression:blood plasma (human)
protein:altered expression:blood plasma (human)		 RGD PMID:22290142 PMID:18632918 RGD:127285797, RGD:149735529 NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486 		JBrowse link
G Cd1d1 CD1d1 antigen ameliorates
exacerbates		 IMP RGD PMID:12938235 PMID:24703850 RGD:127345117, RGD:127345121 NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748 		JBrowse link
G Cd36 CD36 molecule susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to | ClinVar Annotator: match by term: Malaria, susceptibility to		 CTD
OMIM
ClinVar		 PMID:10890433 PMID:18305138 PMID:19403559 PMID:25741868 PMID:28960434 More... NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cd40 CD40 antigen severity IMP RGD PMID:11485931 RGD:11352239 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd40lg CD40 ligand severity IMP RGD PMID:11485931 RGD:11352239 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cish cytokine inducible SH2-containing protein susceptibility ISO ClinVar Annotator: match by term: Malaria, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:20484391 NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO CTD Direct Evidence: marker/mechanism CTD PMID:8730300 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 treatment
disease_progression		 IMP
ISO		 RGD PMID:28892065 PMID:28892065 RGD:38455986, RGD:38455986 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Ephb2 Eph receptor B2 IEP mRNA:increased expression:liver RGD PMID:25784101 RGD:127285023 NCBI chr 4:136,374,850...136,563,637
Ensembl chr 4:136,374,850...136,563,299 		JBrowse link
G Ephb3 Eph receptor B3 ISO RGD PMID:25784101 RGD:127285023 NCBI chr16:21,023,530...21,042,054
Ensembl chr16:21,023,505...21,042,055 		JBrowse link
G Ephb6 Eph receptor B6 IEP RGD PMID:25784101 RGD:127285023 NCBI chr 6:41,581,940...41,597,445
Ensembl chr 6:41,582,416...41,597,443 		JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb IAGP
ISO		 OMIM:609148 | OMIM:611162
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malaria, resistance to		 MouseDO
OMIM
CTD
ClinVar		 PMID:12115230 PMID:15459183 PMID:16115811 PMID:16170323 PMID:17435165 More... NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116 		JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III ISO DNA:missense mutation:cds:p.H131R (human) RGD PMID:19965803 RGD:5147921 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504 		JBrowse link
G Foxp3 forkhead box P3 disease_progression ISO RGD PMID:19338000 PMID:16169501 RGD:38455985, RGD:38455992 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked susceptibility
severity		 ISO DNA:SNPs: :multiple
ClinVar Annotator: match by term: Malaria, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:point mutation:cds:c.968T>C (human)		 ClinVar
CTD
OMIM
RGD		 PMID:5448 PMID:16832 PMID:511159 PMID:736032 PMID:853376 More... RGD:10449111, RGD:10449115 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800 		JBrowse link
G Gypa glycophorin A ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr 8:81,220,674...81,237,414
Ensembl chr 8:81,220,410...81,237,171 		JBrowse link
G Gypc glycophorin C ISO ClinVar Annotator: match by term: Malaria, resistance to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:1991173 PMID:5011657 PMID:8157284 PMID:11719395 PMID:12469115 More... NCBI chr18:32,661,373...32,693,087
Ensembl chr18:32,661,375...32,693,087 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain resistance ISO Hemoglobin C; DNA:polymorphism:CDS:69G>A, amino acid E6K
ClinVar Annotator: match by term: Malaria, resistance to | ClinVar Annotator: match by term: Malaria, susceptibility to
CTD Direct Evidence: marker/mechanism		 RGD
ClinVar
CTD
OMIM		 PMID:14973 PMID:81926 PMID:88735 PMID:893136 PMID:909565 More... RGD:1600894
G Hbb-b2 hemoglobin, beta adult minor chain resistance ISO RGD PMID:11001883 RGD:1600894
G Hmox1 heme oxygenase 1 IAGP OMIM:609148 | OMIM:611162 MouseDO NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hp haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8730300 PMID:16597321 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Icam1 intercellular adhesion molecule 1 susceptibility IAGP
ISO		 OMIM:609148 | OMIM:611162
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to | ClinVar Annotator: match by term: Malaria, susceptibility to
CTD Direct Evidence: marker/mechanism		 MouseDO
ClinVar
CTD
OMIM		 PMID:9259284 PMID:9861406 PMID:10417733 PMID:10699175 PMID:23609612 More... NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Ifng interferon gamma IAGP OMIM:609148 | OMIM:611162 MouseDO NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma ISO ClinVar Annotator: match by term: Malaria, susceptibility to ClinVar PMID:1945893 PMID:3198117 PMID:6805883 PMID:7803800 PMID:8244337 More... NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 IMP RGD PMID:28359899 RGD:39938859 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575 		JBrowse link
G Il21 interleukin 21 exacerbates IMP RGD PMID:25763578 RGD:127285358 NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785 		JBrowse link
G Il27 interleukin 27 ameliorates IMP RGD PMID:24522137 PMID:26968425 RGD:126790512, RGD:11530371 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Il33 interleukin 33 IEP protein:increased expression:serum: RGD PMID:28359899 RGD:39938859 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118 		JBrowse link
G Kir3dl1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 severity ISO DNA:deletion:cds RGD PMID:21889618 RGD:38676475 NCBI chr  X:135,418,748...135,435,055
Ensembl chr  X:135,418,748...135,435,058 		JBrowse link
G LOC111365144 Nos2 promoter region ISO ClinVar Annotator: match by term: Malaria, resistance to ClinVar PMID:12433515 NCBI chr11:78,810,061...78,811,815 JBrowse link
G Ltbr lymphotoxin B receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15788153 NCBI chr 6:125,283,534...125,291,026
Ensembl chr 6:125,283,534...125,290,848 		JBrowse link
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 ISO ClinVar Annotator: match by term: Malaria, susceptibility to ClinVar PMID:20484391 NCBI chr 9:107,132,125...107,167,082
Ensembl chr 9:107,132,126...107,167,076 		JBrowse link
G Mir122 microRNA 122 treatment IEP RGD PMID:28123381 RGD:35673288 NCBI chr18:65,381,932...65,381,997
Ensembl chr18:65,381,932...65,381,997 		JBrowse link
G Mir142 microRNA 142 treatment IEP RGD PMID:28123381 RGD:35673288 NCBI chr11:87,647,690...87,647,753
Ensembl chr11:87,647,690...87,647,753 		JBrowse link
G Mir669n microRNA 669n treatment IEP RGD PMID:28123381 RGD:35673288 NCBI chr 3:115,773,551...115,773,604
Ensembl chr 3:115,773,551...115,773,604 		JBrowse link
G Mir709 microRNA 709 treatment IEP RGD PMID:28123381 RGD:35673288 NCBI chr 8:84,812,728...84,812,815
Ensembl chr 8:84,812,728...84,812,815 		JBrowse link
G Mirlet7a-1 microRNA let7a-1 treatment IEP RGD PMID:28123381 RGD:35673288 NCBI chr13:48,691,655...48,691,748
Ensembl chr13:48,691,655...48,691,748 		JBrowse link
G Mirlet7c-1 microRNA let7c-1 treatment IEP RGD PMID:28123381 RGD:35673288 NCBI chr16:77,396,545...77,396,638
Ensembl chr16:77,396,545...77,396,638 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 IDA associated with Lung Neoplasms RGD PMID:21931708 RGD:6483517 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Ncr3-ps natural cytotoxicity triggering receptor 3, pseudogene susceptibility ISO ClinVar Annotator: match by term: Malaria, severe, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:17208487 NCBI chr17:35,399,512...35,403,785
Ensembl chr17:35,399,511...35,403,638 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO ClinVar Annotator: match by term: Malaria, resistance to | ClinVar Annotator: match by term: Malaria, severe, resistance to | ClinVar Annotator: match by term: Malaria, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:9457101 PMID:12433515 PMID:31995689 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Pklr pyruvate kinase liver and red blood cell susceptibility ISO
IAGP		 DNA:mutations, haplotype:multiple (human)
OMIM:609148 | OMIM:611162
DNA:missense mutation:cds:p.I90N (mouse)		 MouseDO
RGD		 PMID:20377593 PMID:14595440 RGD:11535999, RGD:11537407 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091 		JBrowse link
G Prf1 perforin 1 (pore forming protein) IMP RGD PMID:21525386 RGD:6482803 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459 		JBrowse link
G Procr protein C receptor, endothelial disease_progression ISO RGD PMID:27671831 RGD:126848795 NCBI chr 2:155,592,159...155,597,391
Ensembl chr 2:155,593,037...155,597,391 		JBrowse link
G Slc19a1 solute carrier family 19 (folate transporter), member 1 ISO DNA:SNP::g.80G>A (human) RGD PMID:27198213 RGD:40903062 NCBI chr10:76,868,103...76,886,266
Ensembl chr10:76,868,075...76,896,836 		JBrowse link
G Slc4a1 solute carrier family 4 (anion exchanger), member 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malaria, cerebral, resistance to | ClinVar Annotator: match by term: Malaria, susceptibility to		 CTD
ClinVar		 PMID:1378323 PMID:1722314 PMID:1737855 PMID:2146504 PMID:6338046 More... NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029 		JBrowse link
G Spp1 secreted phosphoprotein 1 IDA RGD PMID:16552072 RGD:1581333 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Tbx21 T-box 21 ISO RGD PMID:19338000 RGD:38455985 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malaria, resistance to		 CTD
OMIM
ClinVar		 PMID:16991088 PMID:17322885 PMID:18305471 PMID:25741868 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587 		JBrowse link
G Tnf tumor necrosis factor susceptibility ISO DNA:polymorphism:promoter:-376G>A
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD
RGD		 PMID:8056188 PMID:9818939 PMID:10369255 PMID:10450718 PMID:11261930 More... RGD:1624967 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 severity ISO DNA:SNP: :rs2234237A>T (human) RGD PMID:27671831 RGD:126848795 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Tslp thymic stromal lymphopoietin IEP mRNA:altered expression:multiple (mouse) RGD PMID:28955823 RGD:38596344 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850 		JBrowse link
Malarial Anemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr4 Fc receptor, IgG, low affinity IV severity
susceptibility		 ISO DNA:polymorphism: :p.F176V (human) RGD PMID:20231419 PMID:23045477 RGD:11040771, RGD:11344971 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330 		JBrowse link
G Slc4a1 solute carrier family 4 (anion exchanger), member 1 severity ISO DNA:snp:promoter:g.-5699T>C (human) RGD PMID:16960783 RGD:10450507 NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029 		JBrowse link
G Tlr9 toll-like receptor 9 susceptibility ISO DNA:SNP:promoter:g.-1237T>C (rs5743836) (human) RGD PMID:23045477 RGD:11344971 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
Neonatal Sepsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camp cathelicidin antimicrobial peptide ameliorates ISO RGD PMID:15645239 RGD:458925287 NCBI chr 9:109,676,445...109,678,524
Ensembl chr 9:109,676,447...109,678,685 		JBrowse link
G Crp C-reactive protein, pentraxin-related treatment ISO RGD PMID:15645239 RGD:458925287 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Il27 interleukin 27 IEP
ISO		 protein:increased expression:blood serum (mouse)
protien:increased expression:blood serum (human)		 RGD PMID:31818960 PMID:22766719 RGD:126790524, RGD:126790543 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) susceptibility ISO DNA:SNP:enhancer: (rs1891320) (human) RGD PMID:20463618 RGD:6482720 NCBI chr 4:138,559,168...138,562,500
Ensembl chr 4:138,559,171...138,562,497 		JBrowse link
Plasmodium falciparum malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility ISO DNA:SNPs,haplotype:multiple RGD PMID:18003641 RGD:39938831 NCBI chr 2:26,732,508...26,754,973
Ensembl chr 2:26,732,515...26,754,991 		JBrowse link
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif 13 ISO protein:decreased activity:plasma (human) RGD PMID:20062916 RGD:10449041 NCBI chr 2:26,863,363...26,899,638
Ensembl chr 2:26,863,428...26,899,640 		JBrowse link
G Bsg basigin ISO CTD Direct Evidence: therapeutic CTD PMID:22080952 PMID:26195724 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G Cast calpastatin ISO protein:alter localization:erythrocyte RGD PMID:17359359 RGD:5509812 NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO mRNA, protein:increased expression:blood, RGD PMID:15972509 RGD:5683898 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509 		JBrowse link
G Clec11a C-type lectin domain family 11, member a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19884328 NCBI chr 7:43,953,190...43,956,383
Ensembl chr 7:43,952,111...43,956,326 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 treatment ISO DNA:polymorphisms:: RGD PMID:10471063 RGD:124713538 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Fas Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625619 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III severity ISO DNA:missense mutation:cds:p.R131H (rs1801274) (human) RGD PMID:18194515 RGD:5147927 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked severity ISO DNA:missense mutation:cds:202G>A (p.V68M) (human) RGD PMID:24943486 RGD:10449113 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 severity ISO RGD PMID:19635899 RGD:10450848 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility ISO DNA:polymorphism:cds:HLA-DQB1*0501 (human) RGD PMID:11076705 RGD:11041780 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20305663
G Hp haptoglobin severity ISO DNA:missense mutation:cds:p.K54E (human) RGD PMID:24478401 RGD:11041793 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:plasma RGD PMID:21985368 RGD:5684362 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO DNA:haplotype:exon: RGD PMID:18396436 RGD:11530064 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Tnf tumor necrosis factor severity ISO protein:increased expression:plasma RGD PMID:1984482 RGD:10450571 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Plasmodium vivax malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr1 atypical chemokine receptor 1 (Duffy blood group) ISO ClinVar Annotator: match by term: Resistance to Plasmodium vivax infection OMIM
ClinVar		 PMID:7663520 PMID:8547665 PMID:8651934 PMID:10570183 PMID:10791881 More... NCBI chr 1:173,159,457...173,161,079
Ensembl chr 1:173,159,453...173,161,317 		JBrowse link
Pregnancy-associated Malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO RGD PMID:24717969 RGD:11041890 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Mir146 microRNA 146 susceptibility ISO miRNA:SNP: (rs2910164) (human) RGD PMID:30642347 RGD:126925184 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
toxic shock syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin treatment ISO RGD PMID:2424486 RGD:10046036 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186 		JBrowse link
G Ace angiotensin I converting enzyme severity ISO DNA:SNP, insertion/deletion:promoter, intron: (rs4291, rs4646994) RGD PMID:28336767 RGD:39939121 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Adk adenosine kinase IMP RGD PMID:8207212 RGD:6482670 NCBI chr14:21,102,622...21,498,637
Ensembl chr14:21,102,642...21,498,637 		JBrowse link
G Adm adrenomedullin ISO RGD PMID:17318497 PMID:17766482 RGD:1625310, RGD:1642599 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Adrb2 adrenergic receptor, beta 2 disease_progression
treatment		 ISO DNA:polymorphism: :rs1042717(human) RGD PMID:19850944 PMID:16076286 RGD:8548487, RGD:8548529 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IAGP RGD PMID:21270403 RGD:6767566 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Aqp1 aquaporin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24028651 NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540 		JBrowse link
G C5ar1 complement component 5a receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18063050 NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465 		JBrowse link
G Cckbr cholecystokinin B receptor ISO mRNA:increased expression:myocardium RGD PMID:15948246 RGD:2311332 NCBI chr 7:105,075,201...105,085,546
Ensembl chr 7:105,074,938...105,120,105 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 disease_progression ISO RGD PMID:28834779 RGD:14995949 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Cd274 CD274 antigen severity ISO protein:increased expression:serum
protein:increased expression:lymphocyte, mononcyte		 RGD PMID:29702526 PMID:26063974 RGD:40822808, RGD:41410786 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Elane elastase, neutrophil expressed treatment ISO RGD PMID:18323746 RGD:10450579 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049 		JBrowse link
G Eno2 enolase 2, gamma neuronal ISO proteiin:increased expression:serum RGD PMID:17083782 RGD:2293748 NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636 		JBrowse link
G F2 coagulation factor II severity ISO protein:decreased expression:blood plasma (human) RGD PMID:2788582 RGD:40822807 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G Fancc Fanconi anemia, complementation group C IMP RGD PMID:17404312 RGD:11045879 NCBI chr13:63,452,519...63,645,126
Ensembl chr13:63,432,857...63,645,092 		JBrowse link
G Gc vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17852808 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO mRNA:decreased expression:polymorphonuclear leukocyte RGD PMID:24465168 RGD:126848796 NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250 		JBrowse link
G H2-Ea histocompatibility 2, class II antigen E alpha disease_progression ISO associated with Burns
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:28771573 PMID:17568330 PMID:15644645 RGD:5490160, RGD:5490203 NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta ISO mRNA:decreased expression:blood RGD PMID:15644645 RGD:5490203 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:18208666 RGD:4145362 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hspa1b heat shock protein 1B susceptibility ISO associated wit community-acquired pneumonia;DNA:SNP: :1267A>G (human) RGD PMID:12771604 RGD:5147601 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 severity ISO protein:increased activity, increased expression:plasma, heart (human) RGD PMID:21765346 RGD:39939075 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma RGD PMID:25403265 RGD:38455982 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il10 interleukin 10 onset
severity		 IAGP
IEP
ISO
IMP		 protein:increased expression:lung (mouse)
protein:increased expression:plasma		 RGD PMID:12117955 PMID:28659355 PMID:25403265 PMID:7593621 RGD:1598471, RGD:40890272, RGD:38455982, RGD:11049456 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il19 interleukin 19 IMP RGD PMID:18246602 RGD:5037232 NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852 		JBrowse link
G Il1b interleukin 1 beta severity IEP protein:increased expression:lung (mouse) RGD PMID:28659355 RGD:40890272 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment
susceptibility		 ISO human gene in a mouse model
associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:polymorphism::		 RGD PMID:15516267 PMID:23014359 RGD:8551736, RGD:11522756 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il20ra interleukin 20 receptor, alpha IEP mRNA:increased expression:multiple RGD PMID:18246602 RGD:5037232 NCBI chr10:19,587,421...19,635,801
Ensembl chr10:19,588,318...19,635,801 		JBrowse link
G Il20rb interleukin 20 receptor beta IEP mRNA:increased expression:multiple RGD PMID:18246602 RGD:5037232 NCBI chr 9:100,339,772...100,368,526
Ensembl chr 9:100,339,772...100,368,841 		JBrowse link
G Il27 interleukin 27 IEP protein, mRNA:increased expression:blood serum, spleen (mouse) RGD PMID:20435892 RGD:126790535 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Il6 interleukin 6 treatment IMP RGD PMID:2124237 RGD:11060276 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO associated with acute pyelonephritis;DNA:SNPs, missense mutations, haplotypes:promoter, cds:multiple RGD PMID:17202308 PMID:17202308 RGD:6903268, RGD:6903268 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Mc2r melanocortin 2 receptor ISO protein:increased expression:liver (rat) RGD PMID:2822467 RGD:6484558 NCBI chr18:68,539,970...68,562,391
Ensembl chr18:68,539,978...68,562,391 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) ISO RGD PMID:17381395 PMID:17565848 RGD:4891013, RGD:1641978 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:29979224 RGD:21081538 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Mir21a microRNA 21a exacerbates
ameliorates		 IMP RGD PMID:28437377 PMID:31189875 RGD:41404641, RGD:41404698 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Mir494 microRNA 494 severity ISO RGD PMID:30783439 RGD:150527846 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836 		JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial susceptibility ISO associated with Burns; DNA:missense mutation:cds:m.4216T>C (human) RGD PMID:19487983 RGD:5148017 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha treatment ISO RGD PMID:11961112 RGD:126928137 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:8745224 PMID:16601845 RGD:1580268 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nppc natriuretic peptide type C ISO protein:increased expression:plasma RGD PMID:8117275 RGD:1642297 NCBI chr 1:86,594,015...86,598,295
Ensembl chr 1:86,594,013...86,598,293 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 IMP RGD PMID:15677345 RGD:8657146 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 IMP RGD PMID:12445868 RGD:10414070 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pdcd1 programmed cell death 1 severity ISO protein:increased expression:serum
protein:increased expression:lymphocyte, mononcyte		 RGD PMID:29702526 PMID:26063974 RGD:40822808, RGD:41410786 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta severity IMP RGD PMID:28659355 RGD:40890272 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028 		JBrowse link
G Plaur plasminogen activator, urokinase receptor IMP RGD PMID:20693875 RGD:6484122 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Proc protein C treatment IMP
ISO		 RGD PMID:19320827 PMID:21850534 RGD:11100015, RGD:11100041 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Ptx3 pentraxin related gene ISO protein:increased expression:plasma (human) RGD PMID:30687307 RGD:38508896 NCBI chr 3:66,127,308...66,133,227
Ensembl chr 3:66,127,331...66,133,226 		JBrowse link
G Ren1 renin 1 structural exacerbates ISO protein:increased activity:blood plasma (human) RGD PMID:31723628 RGD:125097502 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063 		JBrowse link
G Sell selectin, lymphocyte ISO protein:increased expression:plasma RGD PMID:19375498 RGD:5685700 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 treatment ISO RGD PMID:16732381 RGD:1599323 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 susceptibility ISO associated with Pneumonia; DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:20429897 RGD:4144828 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 severity ISO protein:decreased expression:plasma (human) RGD PMID:6158114 RGD:36174004 NCBI chr11:75,300,855...75,313,449
Ensembl chr11:75,300,595...75,313,527 		JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 treatment ISO RGD PMID:8172580 RGD:8661646 NCBI chr 2:84,595,704...84,605,748
Ensembl chr 2:84,595,731...84,605,788 		JBrowse link
G Sftpb surfactant associated protein B ISO associated with Pneumonia;DNA:polymorphism: :1580C>T (human) RGD PMID:15190959 RGD:4143404 NCBI chr 6:72,281,594...72,291,354
Ensembl chr 6:72,281,594...72,291,354 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 severity IMP RGD PMID:19469017 RGD:150573701 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Tbxa2r thromboxane A2 receptor treatment ISO RGD PMID:7816742 RGD:11059599 NCBI chr10:81,164,102...81,171,008
Ensembl chr10:81,164,565...81,171,006 		JBrowse link
G Tfpi tissue factor pathway inhibitor treatment ISO RGD PMID:11776329 RGD:11062085 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119 		JBrowse link
G Thpo thrombopoietin ISO protein:increased expression:serum: RGD PMID:20467749 RGD:10449021 NCBI chr16:20,543,204...20,553,261
Ensembl chr16:20,543,204...20,553,261 		JBrowse link
G Tnf tumor necrosis factor treatment ISO protein:increased expression:peritoneal macrophage, cell surface (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20054000 PMID:2213560 PMID:12622907 RGD:10449465, RGD:1598936 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ISO mRNA:decreased expression:polymorphonuclear leukocyte RGD PMID:24465168 RGD:126848796 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A IMP RGD PMID:23422584 RGD:39938961 NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633 		JBrowse link
Viremia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 ISO associated with Retroviridae Infections; RGD PMID:28381565 RGD:14398820 NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain ISO RGD PMID:29307521 RGD:42724467 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16225
    syndrome 10770
      Systemic Inflammatory Response Syndrome 406
        Sepsis 404
          Fungemia + 4
          Neonatal Sepsis 4
          Parasitemia + 84
          Viremia + 2
          bacterial sepsis + 177
          toxic shock syndrome 62
Path 2
Term Annotations click to browse term
  disease 16225
    Pathological Conditions, Signs and Symptoms 12631
      Pathologic Processes 7995
        Shock 427
          Systemic Inflammatory Response Syndrome 406
            Sepsis 404
              Fungemia + 4
              Neonatal Sepsis 4
              Parasitemia + 84
              Viremia + 2
              bacterial sepsis + 177
              toxic shock syndrome 62
paths to the root