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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Sepsis
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Accession:DOID:9004484 term browser browse the term
Definition:Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Synonyms:exact_synonym: Pyaemia;   Pyaemias;   Pyemia;   Pyemias;   Pyohemias;   blood poisoning;   pyohemia;   septicemia
 narrow_synonym: septic shock;   severe sepsis
 related_synonym: SEPSIS, SUSCEPTIBILITY TO
 xref: HP:0100806;   MESH:D018805


show annotations for term's descendants           Sort by:
Sepsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin ISO mRNA:increased expression:liver RGD PMID:9843780 PMID:15167684 RGD:1598509, RGD:10046033 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229 		JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase severity IAGP DNA:polymorphism:cds:allele A (human) RGD PMID:4375858 RGD:39938844 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024 		JBrowse link
G ACE angiotensin I converting enzyme susceptibility IAGP DNA:insertion/deletion:intron: RGD PMID:19143971 RGD:40400706 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO mRNA, protein:decreasedexpression:serum, omental fat pad: RGD PMID:16488436 PMID:19481767 PMID:21962804 RGD:1599144, RGD:5686835, RGD:5686408 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADM adrenomedullin treatment ISO
EXP
IDA 		protein:increased expression:plasma:
CTD Direct Evidence: marker/mechanism
associated with Jaundice,Obstructive; 		CTD
RGD		 PMID:14766677 PMID:20132852 PMID:19009024 PMID:20132852 RGD:7364952, RGD:7364986, RGD:7364952 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADORA2A adenosine A2a receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:27757725 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G ADORA2B adenosine A2b receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:27757725 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746 		JBrowse link
G ADRA2A adrenoceptor alpha 2A disease_progression ISO RGD PMID:19894027 RGD:6480483 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907 		JBrowse link
G ADRB2 adrenoceptor beta 2 ISO mRNA,protein:decreased expression:liver: RGD PMID:16603198 PMID:10409266 RGD:1598745, RGD:8548498 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G ADRB3 adrenoceptor beta 3 IEP mRNA, protein:increased expression:heart left ventricle (human) RGD PMID:17999941 RGD:2292119 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599 		JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO RGD PMID:19623040 RGD:10402067 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 ISO mRNA:increased expression:duodenum, jejunum, ileum (rat) RGD PMID:12627002 RGD:4144178 NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327 		JBrowse link
G ALB albumin disease_progression IEP protein:decreased expression:serum: RGD PMID:22801198 RGD:11036079 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member treatment ISO associated with heat shock treatment;protein:altered expression, altered phosphorylation:liver, mitochondria (rat) RGD PMID:17607160 RGD:15036802 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ANGPT1 angiopoietin 1 EXP CTD Direct Evidence: therapeutic CTD PMID:16005988 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055 		JBrowse link
G APOA1 apolipoprotein A1 treatment ISO RGD PMID:19561306 RGD:7241869 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ARG2 arginase 2 ISO protein:decreased expression:lung RGD PMID:9635249 RGD:1626297 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G ATM ATM serine/threonine kinase treatment ISO RGD PMID:24184056 RGD:126781746 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO RGD PMID:28446393 RGD:13782063 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466 		JBrowse link
G BAAT bile acid-CoA:amino acid N-acyltransferase ISO RGD PMID:7575455 RGD:69770 NCBI chr 9:101,360,417...101,385,006
Ensembl chr 9:101,354,182...101,385,400 		JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO protein:increased localization:mitochondrion RGD PMID:24011917 PMID:22683079 RGD:10053647, RGD:10053707 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G C3 complement C3 ISO protein:increased expression:liver
mRNA:increased expression:kidney 		RGD PMID:3339873 PMID:24154627 RGD:7411622, RGD:11040886 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C5 complement C5 ISO protein:increased activation:plasma RGD PMID:18648551 PMID:14688199 RGD:5130170, RGD:1600599 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195 		JBrowse link
G C5AR1 complement C5a receptor 1 disease_progression ISO RGD PMID:12897064 PMID:18648551 RGD:5130176, RGD:5130170 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G C6 complement C6 severity ISO RGD PMID:15638131 RGD:1600672 NCBI chr 5:41,142,116...41,261,469
Ensembl chr 5:41,142,116...41,261,438 		JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S ISO protein:decreased expression:diaphragmaticus muscle RGD PMID:28044347 RGD:329849111 NCBI chr 1:201,039,512...201,112,426
Ensembl chr 1:201,039,512...201,112,451 		JBrowse link
G CAMP cathelicidin antimicrobial peptide ISO RGD PMID:17142779 RGD:2316243 NCBI chr 3:48,223,495...48,225,485
Ensembl chr 3:48,223,347...48,225,491 		JBrowse link
G CASP3 caspase 3 treatment ISO
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16003065 PMID:32062619 PMID:29180187 RGD:13782295 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP6 caspase 6 ISO protein:increased activity:thymus, T cell RGD PMID:11086028 RGD:2301332 NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583 		JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:18570579 PMID:29180187 RGD:2311435, RGD:13782295 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:29180187 RGD:13782295 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAST calpastatin ISO RGD PMID:15563579 RGD:5683871 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595
Ensembl chr 5:96,247,756...96,779,595 		JBrowse link
G CAT catalase severity ISO RGD PMID:15836852 RGD:9068893 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CBS cystathionine beta-synthase susceptibility IAGP DNA:SNP:intron (rs6586282, rs34758144) (human) RGD PMID:26508567 RGD:40903018 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 ISO RGD PMID:21652218 RGD:7248417 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO mRNA:increased expression:ileum RGD PMID:19111613 RGD:2307002 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 severity IEP RGD PMID:21208283 RGD:5683911 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:plasma (rat) RGD PMID:18290317 RGD:4890036 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CD163 CD163 molecule IEP protein:increased expression:blood serum, CD-14 positive monocyte (human) RGD PMID:24637679 RGD:127285802 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893 		JBrowse link
G CD1D CD1d molecule treatment ISO RGD PMID:14572776 RGD:127345103 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G CD274 CD274 molecule disease_progression IEP protein:increased expression:monocyte
protein:increased expression:B cell,CD4T cell 		RGD PMID:30595665 PMID:27156867 PMID:29702526 PMID:29661225 RGD:40818235, RGD:41412183, RGD:40822808, RGD:40818424 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD28 CD28 molecule severity IEP Higher soluble CD28 in patients who died RGD PMID:17989345 RGD:5131622 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,517...203,739,756 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) ISO RGD PMID:22327076 RGD:6893490 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD40 CD40 molecule IDA protein:decreased nitrosylation:monocyte RGD PMID:20473113 RGD:5490974 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand ISO mRNA:increased expression:heart (rat) RGD PMID:20933523 RGD:11352671 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO RGD PMID:10451498 RGD:10043817 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO protein:increased expression:skeletal muscle RGD PMID:11792653 RGD:625506 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690 		JBrowse link
G CEBPD CCAAT enhancer binding protein delta ISO protein:increased expression:skeletal muscle RGD PMID:11792653 RGD:625506 NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164 		JBrowse link
G CFB complement factor B treatment ISO RGD PMID:24154627 RGD:11040886 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086 		JBrowse link
G CFH complement factor H treatment ISO
IDA 		protein:decreased expression:plasma:
associated with Jaundice,Obstructive; 		RGD PMID:20132852 PMID:19009024 PMID:20132852 RGD:7364952, RGD:7364986, RGD:7364952 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476 		JBrowse link
G CPB2 carboxypeptidase B2 ISO protein:increased activity:plasma: RGD PMID:15497025 RGD:2313648 NCBI chr13:46,053,186...46,105,033
Ensembl chr13:46,053,186...46,105,033 		JBrowse link
G CRH corticotropin releasing hormone ISO protein:increased expression:hypothalamus (rat) RGD PMID:21549066 RGD:5490558 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464 		JBrowse link
G CRP C-reactive protein ISO
IEP 		protein:increased expression:blood: RGD PMID:21797109 PMID:19060982 RGD:6482315, RGD:9491784 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CS citrate synthase ISO protein:decreased expression:cerebral cortex RGD PMID:25299715 RGD:329337347 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391 		JBrowse link
G CSF2 colony stimulating factor 2 IEP protein:increased expression:plasma: RGD PMID:10664226 RGD:10449523 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA
EXP 		CTD Direct Evidence: therapeutic CTD
RGD		 PMID:17505274 PMID:8706460 RGD:11039434 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 IEP protein:increased expression:lung, macrophage RGD PMID:19733456 RGD:4144897 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO RGD PMID:9284162 RGD:5135255 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 ISO protein:increased expression:multiple tissues RGD PMID:9284162 RGD:5135255 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO protein:increased expression:multiple tissues RGD PMID:9284162 RGD:5135255 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 exacerbates IEP protein:increased expression:blood plasma (human) RGD PMID:31818332 RGD:40924635 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17138957 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA, protein:decreased expression:liver RGD PMID:15665729 RGD:5147745 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO RGD PMID:18360687 PMID:15665729 RGD:2303376, RGD:5147745 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO RGD PMID:15665729 RGD:5147745 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO RGD PMID:15190971 RGD:1625384 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773 		JBrowse link
G EDN1 endothelin 1 ISO mRNA, protein:increased expression:multiple (rat) RGD PMID:10838194 RGD:8662298 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon ISO protein:increased serine phosphorylation:gastrocnemius RGD PMID:12376332 RGD:11041880 NCBI chr 3:184,135,358...184,145,311
Ensembl chr 3:184,135,038...184,146,127 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO RGD PMID:8141277 RGD:10395355 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G EIF4E eukaryotic translation initiation factor 4E ISO RGD PMID:17709445 RGD:10401144 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133 		JBrowse link
G ELANE elastase, neutrophil expressed ISO associated with Klebsiella Infections; RGD PMID:9585238 RGD:10450543 NCBI chr19:852,303...856,243
Ensembl chr19:851,014...856,247 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO protein:increased activity:lymphocyte: RGD PMID:22645477 RGD:9685487 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G EP300 E1A binding protein p300 ISO mRNA, protein:increased expression:muscle part of extensor digitorum longus (rat) RGD PMID:20538901 RGD:7364733 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:16755255 RGD:5508850 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G F11 coagulation factor XI ISO RGD PMID:12000738 RGD:1598921 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681 		JBrowse link
G F2 coagulation factor II, thrombin treatment ISO
IEP 		RGD PMID:19705256 PMID:12361199 RGD:7387324, RGD:10449428 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G F3 coagulation factor III, tissue factor treatment IEP
ISO 		RGD PMID:9875912 PMID:26311287 RGD:11340217, RGD:11341736 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G F5 coagulation factor V severity
treatment 		IAGP
ISO 		RGD PMID:16235188 PMID:12000738 RGD:4892622, RGD:1598921 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588 		JBrowse link
G F7 coagulation factor VII treatment ISO protein:decreased activity:plasma (rat) RGD PMID:3660344 PMID:12000738 RGD:2312320, RGD:1598921 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685 		JBrowse link
G F9 coagulation factor IX treatment ISO RGD PMID:12000738 RGD:1598921 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459 		JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:liver RGD PMID:17899301 RGD:2290175 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand ISO mRNA:increased expression:liver RGD PMID:17899301 RGD:2290175 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FGA fibrinogen alpha chain ISO protein:decreased expression:serum (rat) RGD PMID:24667622 RGD:9685020 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 disease_progression IEP Pneumonia associated sepsis RGD PMID:21219633 RGD:4891938 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FOXP3 forkhead box P3 severity IEP RGD PMID:25403265 RGD:38455982 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO protein:decreased phosphorylation, decreased activity:T cell (rat) RGD PMID:9551931 RGD:2324866 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G GAS6 growth arrest specific 6 IDA RGD PMID:16374177 RGD:1579935 NCBI chr13:113,820,549...113,864,076
Ensembl chr13:113,820,549...113,864,076 		JBrowse link
G GATA3 GATA binding protein 3 severity IEP RGD PMID:25403265 RGD:38455982 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G GCH1 GTP cyclohydrolase 1 treatment ISO associated with Staphylococcal Infections RGD PMID:12441764 PMID:29428597 RGD:401700401, RGD:401717570 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G GFER growth factor, augmenter of liver regeneration ISO protein:increased expression:serum: RGD PMID:23073658 RGD:9685733 NCBI chr16:1,984,193...1,987,749
Ensembl chr16:1,984,193...1,987,749 		JBrowse link
G GHR growth hormone receptor ISO RGD PMID:11126270 RGD:2307382 NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO mRNA,protein:decreased expression:aorta,heart, intestine, plasma: RGD PMID:15155262 RGD:12905047 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947 		JBrowse link
G GHSR growth hormone secretagogue receptor disease_progression ISO RGD PMID:15155262 RGD:12905047 NCBI chr 3:172,443,291...172,448,456
Ensembl chr 3:172,443,291...172,448,456 		JBrowse link
G GJA5 gap junction protein alpha 5 ISO mRNA, protein:increased expression:aorta endothelium RGD PMID:15942348 RGD:7207815 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362 		JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha exacerbates ISO associated with thrombocytopenia RGD PMID:24150174 RGD:42722621 NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023 		JBrowse link
G GPT glutamic--pyruvic transaminase treatment ISO RGD PMID:26814114 PMID:25243423 RGD:14975161, RGD:401717564 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO protein:increased expression:lung (rat) RGD PMID:19837828 RGD:2325949 NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,183,337 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 IEP protein: increased expression: neutrophils RGD PMID:16849637 RGD:5688378 NCBI chr11:67,266,473...67,286,556
Ensembl chr11:67,266,473...67,286,556 		JBrowse link
G GRK5 G protein-coupled receptor kinase 5 IEP protein: increased expression: neutrophils RGD PMID:16849637 RGD:5688378 NCBI chr10:119,207,571...119,459,745
Ensembl chr10:119,207,571...119,459,745 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO protein:decreased phosphorylation,increased activity: : RGD PMID:20926980 RGD:10045370 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSN gelsolin IEP protein:decreased expression:blood serum (human) RGD PMID:9142022 RGD:329333022 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 disease_progression IEP RGD PMID:23131280 RGD:7245480 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:23925573 RGD:9681446 NCBI chr 2:239,048,168...239,401,649
NCBI chr 2:239,193,331...239,195,457
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G HDAC6 histone deacetylase 6 ISO RGD PMID:20538901 RGD:7364733 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G HMGB1 high mobility group box 1 treatment ISO
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19265175 PMID:23146691 PMID:19623040 PMID:20936717 RGD:10402067, RGD:10402173 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase ISO protein: decreased expression RGD PMID:9603077 RGD:5688768 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO associated with burns;protein:decreased expression:skeletal muscle RGD PMID:16483253 PMID:23143056 RGD:1624233, RGD:10402864 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G HTRA2 HtrA serine peptidase 2 treatment ISO RGD PMID:23557966 RGD:10402934 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO mRNA:increased expression:brain (rat) RGD PMID:20451670 RGD:4145409 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 treatment ISO RGD PMID:25114116 RGD:39938864 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:3597002 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IFNG interferon gamma treatment EXP
ISO
IDA 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9806674 PMID:27598601 PMID:28711488 RGD:14975121, RGD:14974250 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL10 interleukin 10 treatment ISO
EXP 		protein:increased expression:serum
CTD Direct Evidence: therapeutic 		CTD
RGD		 PMID:11441115 PMID:19371254 PMID:27488951 PMID:28108420 PMID:24055021 RGD:2311053, RGD:14975262, RGD:14975261, RGD:7364867 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12B interleukin 12B ISO protein:increased expression:peritoneal fluid, plasma RGD PMID:15776385 RGD:4888507 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL13 interleukin 13 ISO protein:decreased expression:ileum RGD PMID:10679115 PMID:21159497 RGD:4145654, RGD:8549643 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL16 interleukin 16 ISO associated with Shock, Hemorrhagic;protein:increased expression:lung RGD PMID:19641139 RGD:5024925 NCBI chr15:81,182,712...81,314,058
Ensembl chr15:81,159,575...81,314,058 		JBrowse link
G IL17A interleukin 17A ISO RGD PMID:15776385 RGD:4888507 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL17D interleukin 17D severity
treatment 		ISO
IEP 		protein:increased expression:blood serum (human) RGD PMID:31634237 PMID:31634237 PMID:31634237 RGD:40903064, RGD:40903064, RGD:40903064 NCBI chr13:20,701,513...20,723,098
Ensembl chr13:20,702,127...20,723,098 		JBrowse link
G IL1B interleukin 1 beta treatment ISO
EXP 		protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:32062619 PMID:17529909 PMID:21429520 RGD:1626657, RGD:7175319 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 severity ISO RGD PMID:30001716 RGD:39938964 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility
disease_progression
severity 		ISO
IAGP
IDA
IEP 		mRNA, protein:increased expression:lung
associated with Premature Birth;DNA:polymorphism::
DNA:repeats: :
mRNA:increased expression:pituitary gland (rat)
protein:increased expression:serum (human) 		RGD PMID:20454520 PMID:22882323 PMID:11876758 PMID:10048466 PMID:8196140 More... RGD:4142852, RGD:12910846, RGD:11528543, RGD:7175061, RGD:6909139, RGD:6907358 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL22 interleukin 22 ISO protein:increased expression:plasma RGD PMID:19664145 RGD:5147412 NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604 		JBrowse link
G IL27 interleukin 27 exacerbates
severity
disease_progression 		IEP
ISO
IAGP 		protein:increased expression:blood (human)
mRNA:increased expression:blood, leukocyte (human)
associated with Herpesviridae Infections;protein:increased expression:blood serum, spleen (mouse)
DNA:SNP:promoter:-964A>G (rs153109) (human) 		RGD PMID:22965735 PMID:18227999 PMID:20493722 PMID:26767500 PMID:30268141 RGD:126790502, RGD:126790544, RGD:126790537, RGD:126790536, RGD:126790509 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL33 interleukin 33 severity ISO
IEP 		protein:increased expression:plasma,lung
protein:increased expression:plasma, peritoneal fluid:
protein:increased expression:plasma: 		RGD PMID:29672927 PMID:29935165 PMID:29935165 PMID:25665614 RGD:39939028, RGD:40400895, RGD:40400895, RGD:40400739 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL4 interleukin 4 IEP protein:increased expression:plasma RGD PMID:25403265 RGD:38455982 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 treatment ISO
EXP 		associated with Diabetes Mellitus, Non-Insulin-Dependent; mRNA, protein:increased expression:liver, extracellular space (rat)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:32062619 PMID:19079684 PMID:27598601 PMID:25317848 RGD:2307280, RGD:14975121, RGD:11062009 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 ISO RGD PMID:23073793 RGD:7495805 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G IRS1 insulin receptor substrate 1 ISO protein:decreased tyrosine phosphorylation, increased serine phosphorylation:gastrocnemius RGD PMID:19781177 RGD:6482862 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G ITGA4 integrin subunit alpha 4 IEP protein:increased expression:neutrophil RGD PMID:19011162 RGD:13593535 NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940 		JBrowse link
G ITGAM integrin subunit alpha M exacerbates ISO protein:increased expression:neutrophil (rat) RGD PMID:9151199 RGD:329902068 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G JAK2 Janus kinase 2 treatment ISO RGD PMID:24228589 RGD:10411888 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO RGD PMID:21799073 RGD:6892955 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KLKB1 kallikrein B1 ISO RGD PMID:22352684 RGD:7297048 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 susceptibility ISO associated with Gram-Negative Bacterial Infections RGD PMID:28087665 RGD:38676493 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G LBP lipopolysaccharide binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:22167001 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LCN2 lipocalin 2 exacerbates ISO RGD PMID:22786765 RGD:126781712 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LEP leptin ISO RGD PMID:18575315 RGD:5128818 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LIPC lipase C, hepatic type ISO protein:decreased expression:diaphragm, heart, adipose tissue (rat) RGD PMID:2113037 RGD:2308797 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LPA lipoprotein(a) IEP protein:decreased expression:plasma RGD PMID:10764684 RGD:5509915 NCBI chr 6:160,531,482...160,664,275
Ensembl chr 6:160,531,482...160,664,275 		JBrowse link
G LTA lymphotoxin alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:22977509 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G LTF lactotransferrin IDA RGD PMID:23425819 RGD:7243861 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15489642 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15489642 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 treatment ISO RGD PMID:14662889 RGD:126928138 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP associated with Premature Birth;DNA:polymorphism:exon: RGD PMID:22882323 RGD:12910846 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MFN2 mitofusin 2 ISO mRNA:decreased expression:liver (rat) RGD PMID:24720571 RGD:13204837 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIF macrophage migration inhibitory factor IEP
EXP 		protein:increased expression:serum
CTD Direct Evidence: therapeutic 		CTD
RGD		 PMID:9892616 PMID:17585860 RGD:4891012 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR143 microRNA 143 exacerbates ISO RGD PMID:30546393 RGD:155883166 NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023 		JBrowse link
G MIR146A microRNA 146a ISO miRNA:increased expression:myocardium, blood serum (mouse) RGD PMID:26048146 RGD:126925143 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MIR155 microRNA 155 IEP
ISO 		RGD PMID:27434558 PMID:29979224 RGD:21079467, RGD:21081538 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR223 microRNA 223 IEP RNA:increased expression:plasma: RGD PMID:24680405 RGD:21408586 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979 		JBrowse link
G MIR483 microRNA 483 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32062619 NCBI chr11:2,134,134...2,134,209
Ensembl chr11:2,134,134...2,134,209 		JBrowse link
G MIR494 microRNA 494 IEP RNA:decreased expression:plasma RGD PMID:31002148 RGD:155900762 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:23478082 RGD:8549749 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP2 matrix metallopeptidase 2 treatment ISO RGD PMID:23479197 RGD:8657110 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16003065 PMID:23479197 RGD:8657110 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase ISO RGD PMID:18424617 RGD:5130966 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MT-CYB mitochondrially encoded cytochrome b ISO protein:decreased expression:mitochondrion, skeletal muscle RGD PMID:6128308 RGD:2298978 NCBI chr MT:14,747...15,887
Ensembl chr MT:14,747...15,887 		JBrowse link
G MT1X metallothionein 1X ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374846 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MT2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374846 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:20577146 RGD:10041013 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MYLK myosin light chain kinase IAGP RGD PMID:16399953 RGD:1581052 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332 		JBrowse link
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 ISO RGD PMID:22952679 RGD:13801198 NCBI chr10:100,523,729...100,529,923
Ensembl chr10:100,523,668...100,530,000 		JBrowse link
G NEFH neurofilament heavy chain severity IEP RGD PMID:30677080 RGD:27226881 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390 		JBrowse link
G NEFL neurofilament light chain disease_progression IEP RGD PMID:30677080 RGD:27226881 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NFKBIA NFKB inhibitor alpha treatment ISO RGD PMID:14662889 RGD:126928138 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility IAGP
ISO 		DNA:missense mutations, frameshift mutation:cds:p.R702W, p.G908R, 3020_3021insC (human)
mRNA:increased expression:intestine mucosa (rat) 		RGD PMID:21460759 PMID:24059417 RGD:5508752, RGD:8547531 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:17191663 RGD:1642148 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO
EXP 		associated with lung injury
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:17138957 PMID:20035746 PMID:21184738 PMID:15665729 RGD:4891414, RGD:5147745 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 IEP
EXP 		protein:increased expression:heart
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:20035746 PMID:17999941 RGD:2292119 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOX1 NADPH oxidase 1 ameliorates ISO RGD PMID:22982050 RGD:329955362 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment ISO protein:decreased expression:alveolar macrophage RGD PMID:21057058 PMID:21787473 RGD:4892317, RGD:7174711 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G OTC ornithine transcarbamylase ISO mRNA:decreased expression:liver (rat) RGD PMID:10353541 RGD:4144069 NCBI chr  X:38,327,684...38,422,928
Ensembl chr  X:38,327,598...38,422,908 		JBrowse link
G PDCD1 programmed cell death 1 disease_progression IEP
ISO 		protein:increased expression:T cell
protein:increased expression:B cell,CD4T cell 		RGD PMID:30595665 PMID:27156867 PMID:29702526 PMID:29661225 PMID:19332785 RGD:40818235, RGD:41412183, RGD:40822808, RGD:40818424, RGD:40818273 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PDCD1LG2 programmed cell death 1 ligand 2 IEP protein:increased expression:CD27B cell RGD PMID:29661225 RGD:40818424 NCBI chr 9:5,510,531...5,571,282
Ensembl chr 9:5,510,531...5,571,282 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 disease_progression ISO protein:increased expression:myeloid suppressor cell (mouse) RGD PMID:22451518 RGD:6771205 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PGF placental growth factor ISO protein:increased expression:plasma RGD PMID:16702604 RGD:6483601 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:20508212 RGD:6482683 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO protein:increased activity:liver RGD PMID:9879654 RGD:1642481 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PLAT plasminogen activator, tissue type treatment ISO RGD PMID:12000738 RGD:1598921 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLAU plasminogen activator, urokinase disease_progression IEP Pneumonia associated sepsis RGD PMID:21219633 RGD:4891938 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor IEP protein:increased expression:plasma RGD PMID:22550400 RGD:6483789 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha severity IEP RNA:decreased expression:blood:associated with more severe disease RGD PMID:22089192 RGD:5562037 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO mRNA:decreased expression:skeletal muscle RGD PMID:20647557 RGD:6484531 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPARGC1B PPARG coactivator 1 beta ISO mRNA:decreased expression:skeletal muscle RGD PMID:20647557 RGD:6484531 NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022 		JBrowse link
G PPIA peptidylprolyl isomerase A treatment ISO RGD PMID:29680745 RGD:150429626 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564 		JBrowse link
G PRKCQ protein kinase C theta ISO protein:decreased expression:lymphocyte RGD PMID:11735277 RGD:1625613 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment
disease_progression 		IDA
EXP
ISO 		CTD Direct Evidence: therapeutic
mRNA, protein:decreased expression:liver, plasma 		CTD
RGD		 PMID:11820775 PMID:17556722 PMID:22940033 PMID:15241104 RGD:11100029, RGD:11250412 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242 		JBrowse link
G PVT1 Pvt1 oncogene ISO RNA:increased expression:myocardium RGD PMID:30546393 RGD:155883166 NCBI chr 8:127,794,524...128,101,256
Ensembl chr 8:127,794,513...128,188,202 		JBrowse link
G RAC1 Rac family small GTPase 1 IEP mRNA:increased expression:blood serum (human) RGD PMID:33174038 RGD:152998912 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:nucleus, lung RGD PMID:17626913 RGD:2298853 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RETN resistin IEP protein:increased expression:serum RGD PMID:19545363 RGD:7207151 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 no_association
ameliorates 		ISO RGD PMID:23835476 PMID:32152555 PMID:22195746 RGD:127229908, RGD:127229919, RGD:127229909 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G RPL4 ribosomal protein L4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27978524 NCBI chr15:66,498,015...66,504,855
Ensembl chr15:66,498,015...66,524,532 		JBrowse link
G RPL9 ribosomal protein L9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27978524 NCBI chr 4:39,454,124...39,458,922
Ensembl chr 4:39,452,587...39,458,931 		JBrowse link
G RXRA retinoid X receptor alpha ISO protein:altered localization:liver
protein:decreased expression:liver 		RGD PMID:19008781 PMID:17483744 RGD:2317466, RGD:1643106 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G RYR1 ryanodine receptor 1 ISO mRNA:increased expression:fast muscle tissue
protein:decreased expression:diaphragmaticus muscle 		RGD PMID:18520643 PMID:28044347 RGD:329849107, RGD:329849111 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273 		JBrowse link
G S100B S100 calcium binding protein B IEP RGD PMID:19809934 RGD:5508796 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SELL selectin L ISO RGD PMID:16026013 PMID:15677732 RGD:5685706, RGD:5686285 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702 		JBrowse link
G SELP selectin P ISO protein:increased expression:multiple RGD PMID:20690979 RGD:6478679 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
G SERPINE1 serpin family E member 1 treatment IEP
ISO 		associated with Pneumonia; protein:increased expression:plasma RGD PMID:19753144 PMID:12000738 RGD:4144830, RGD:1598921 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SLC38A2 solute carrier family 38 member 2 ISO RGD PMID:20338592 RGD:9999218 NCBI chr12:46,358,188...46,372,773
Ensembl chr12:46,358,188...46,372,773 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 ISO mRNA:decreased expression:liver RGD PMID:10500057 RGD:631887 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO protein:increased expression:gastrocnemius
mRNA:increased expression:liver 		RGD PMID:12644450 PMID:11312157 RGD:2298924, RGD:634751 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G SOCS2 suppressor of cytokine signaling 2 ISO protein:increased expression:gastrocnemius RGD PMID:12644450 RGD:2298924 NCBI chr12:93,569,969...93,626,236
Ensembl chr12:93,569,814...93,583,487 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO protein:increased expression:gastrocnemius
mRNA:increased expression:liver 		RGD PMID:12644450 PMID:11312157 RGD:2298924, RGD:634751 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:26266917 RGD:11035300 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 ISO mRNA, protein:increased expression:lung RGD PMID:26266917 RGD:11035300 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOD3 superoxide dismutase 3 ISO RGD PMID:26266917 RGD:11035300 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO protein:increased activity:liver, lung, small intestine RGD PMID:17067487 RGD:2291905 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment ISO RGD PMID:24228589 RGD:10411888 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 ISO RGD PMID:11257135 RGD:7207876 NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 severity ISO RGD PMID:11257135 RGD:7207876 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G TBX21 T-box transcription factor 21 severity IEP RGD PMID:25403265 RGD:38455982 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
G TFPI tissue factor pathway inhibitor ISO protein:decreased activity:plasma: RGD PMID:15497025 RGD:2313648 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G TGFB1 transforming growth factor beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16003065 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFBI transforming growth factor beta induced EXP CTD Direct Evidence: marker/mechanism CTD PMID:27887929 NCBI chr 5:136,028,988...136,063,818
Ensembl chr 5:136,028,988...136,063,818 		JBrowse link
G THBD thrombomodulin ISO RGD PMID:17577447 RGD:2312462 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G TLR2 toll like receptor 2 ISO associated with Burns;mRNA:increased expression:liver, lung, kidney
associated with Liver Diseases;mRNA:increased expression:liver 		RGD PMID:14604479 PMID:12831613 PMID:19489280 RGD:2312732, RGD:1302750, RGD:2312497 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 ISO
EXP 		associated with Liver Diseases;mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:20624996 PMID:19489280 PMID:14604479 RGD:2312497, RGD:2312732 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 IEP mRNA:increased expression:plasma RGD PMID:31002148 RGD:155900762 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TNF tumor necrosis factor treatment ISO
EXP 		mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:8741040 PMID:9806674 PMID:15489642 PMID:19695174 PMID:27488951 More... RGD:4144094, RGD:14975262, RGD:7364867, RGD:5147745 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TOP2A DNA topoisomerase II alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:27978524 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TPP2 tripeptidyl peptidase 2 ISO mRNA, protein:increased expression, increased activity:extensor digitorum longus (rat) RGD PMID:12147224 RGD:634435 NCBI chr13:102,596,986...102,679,958
Ensembl chr13:102,596,958...102,679,958 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 disease_progression
treatment 		IEP
ISO 		mRNA:decreased expression:polymorph nuclear cell: RGD PMID:22809118 PMID:22147417 PMID:22996209 RGD:126925981, RGD:127284847, RGD:126925987 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,100...41,286,682 		JBrowse link
G TSLP thymic stromal lymphopoietin treatment
disease_progression 		ISO protein:increased expression:peritoneum, plasma (mouse) RGD PMID:24990542 PMID:26934097 RGD:38549375, RGD:38596335 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026 		JBrowse link
G XDH xanthine dehydrogenase treatment ISO RGD PMID:19751566 RGD:7247648 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
G XIAP X-linked inhibitor of apoptosis IAGP ClinVar Annotator: match by term: Sepsis ClinVar PMID:17080092 PMID:21119115 PMID:25666262 PMID:25741868 PMID:27747465 More... NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
Bacteremia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ISO associated with Experimental Liver Cirrhosis; protein:decreased expression:serum RGD PMID:11349015 RGD:408395143 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 IEP associated with Febrile Neutropenia;protein:increased expression:serum (human) RGD PMID:22584776 RGD:11528568 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO associated with alcohol use disorder;mRNA:increased expression:bone marrow (mouse) RGD PMID:28784931 RGD:40903040 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690 		JBrowse link
G CFH complement factor H IDA associated with Meningococcal Infections; RGD PMID:22104107 RGD:7364945 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476 		JBrowse link
G CISH cytokine inducible SH2 containing protein susceptibility IAGP
EXP 		ClinVar Annotator: match by term: Bacteremia, susceptibility to, 2
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM		 PMID:20484391 NCBI chr 3:50,606,489...50,611,774
Ensembl chr 3:50,606,489...50,611,774 		JBrowse link
G CPB2 carboxypeptidase B2 ISO protein:decreased activity:plasma RGD PMID:17911187 RGD:2313646 NCBI chr13:46,053,186...46,105,033
Ensembl chr13:46,053,186...46,105,033 		JBrowse link
G CRP C-reactive protein IEP protein:increased expression:serum: RGD PMID:18443549 RGD:9491402 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF2 colony stimulating factor 2 treatment ISO RGD PMID:2192004 RGD:10449532 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G FCGR2A Fc gamma receptor IIa IAGP associated with Pneumonia;DNA:SNP: :p.H131R (rs1801274) (human) RGD PMID:21317643 RGD:5147986 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase severity IMP RGD PMID:11565076 RGD:5508478 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO mRNA:increased expression:lung,thymus,spleen: RGD PMID:24891762 RGD:11354979 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL17A interleukin 17A IEP associated with Respiratory Distress Syndrome, Adult; protein:increased expression:serum RGD PMID:21062445 RGD:5128683 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL27 interleukin 27 HEP protein:increased expression:blood serum (human) RGD PMID:26514771 RGD:126790515 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 ISO protein:increased expression:liver, serum RGD PMID:33348064 RGD:40907057 NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688 		JBrowse link
G LOC129936806 ATAC-STARR-seq lymphoblastoid silent region 14400 IAGP ClinVar Annotator: match by term: Bacteremia, susceptibility to, 2 ClinVar PMID:20484391 NCBI chr 3:50,611,643...50,612,122 JBrowse link
G MAPKAPK3 MAPK activated protein kinase 3 IAGP ClinVar Annotator: match by term: Bacteremia, susceptibility to, 2 ClinVar PMID:20484391 NCBI chr 3:50,611,520...50,649,291
Ensembl chr 3:50,611,520...50,649,291 		JBrowse link
G MBL2 mannose binding lectin 2 treatment IAGP associated with Multiple Myeloma:DNA:polymorphism:exon: RGD PMID:16953214 RGD:11530047 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 severity IAGP associated with Staphylococcal Infections; RGD PMID:24086711 RGD:13204726 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PLAT plasminogen activator, tissue type EXP CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor severity IEP RGD PMID:21332843 RGD:6483799 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G SERPINC1 serpin family C member 1 treatment IDA RGD PMID:2679067 RGD:11035251 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327 		JBrowse link
G SOD2 superoxide dismutase 2 ISO mRNA:increased expression:liver: RGD PMID:24253037 RGD:26923958 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G TIRAP TIR domain containing adaptor protein IAGP
EXP 		ClinVar Annotator: match by term: Bacteremia, susceptibility to, 1
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD		 PMID:16991088 PMID:17322885 PMID:18305471 PMID:25741868 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR4 toll like receptor 4 susceptibility IAGP DNA:polymorphisms:cds:p.D299G, T399I (human) RGD PMID:18180796 RGD:4144194 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
bacterial sepsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM1 triggering receptor expressed on myeloid cells 1 treatment
ameliorates
exacerbates 		IDA
ISO 		associated with bacterial pneumonia RGD PMID:21507332 PMID:16960786 PMID:17230441 RGD:126925982, RGD:127229902, RGD:126928125 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,100...41,286,682 		JBrowse link
Candidemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule ameliorates ISO associated with endotoxemia RGD PMID:32154791 RGD:127345119 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G EPHB2 EPH receptor B2 exacerbates ISO RGD PMID:33685996 RGD:127229905 NCBI chr 1:22,710,838...22,921,500
Ensembl chr 1:22,710,839...22,921,500 		JBrowse link
cerebral malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 susceptibility IAGP DNA:SNP:intron 1: C>T RGD PMID:20117248 RGD:40818420 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G AQP4 aquaporin 4 disease_progression ISO protein:increased expression:astrocyte: RGD PMID:21904632 RGD:8698661 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771 		JBrowse link
G CAST calpastatin ISO protein:increased express:brain RGD PMID:16236382 RGD:5509817 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595
Ensembl chr 5:96,247,756...96,779,595 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) ISO RGD PMID:17367535 RGD:6893527 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CLEC12A C-type lectin domain family 12 member A ameliorates ISO RGD PMID:31269448 RGD:41412201 NCBI chr12:9,951,268...10,006,150
Ensembl chr12:9,951,316...9,995,694 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 treatment ISO RGD PMID:25682948 RGD:40400741 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL33 interleukin 33 treatment ISO protein:increased expression:brain RGD PMID:25659095 PMID:25682948 RGD:39938955, RGD:40400741 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G JAK3 Janus kinase 3 ISO RGD PMID:22363534 RGD:11531103 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071 		JBrowse link
G LTA lymphotoxin alpha ISO RGD PMID:12021316 RGD:10449455 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G NRG1 neuregulin 1 treatment ISO
IDA 		mRNA, protein:increased expression:cerebral cortex (mouse)
human protein in a mouse model 		RGD PMID:29636063 PMID:24433482 RGD:39456084, RGD:39456102 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:25775137 RGD:38599200 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 ISO mRNA:decreased expression:brain (mouse) RGD PMID:29107705 RGD:39456137 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO RGD PMID:12228317 RGD:5131158 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
Endotoxemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO mRNA:decreased expression:liver (rat) RGD PMID:26977098 RGD:11041000 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 ISO RGD PMID:9828229 RGD:1598596 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO RGD PMID:16572733 RGD:1598611 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC8 ATP binding cassette subfamily C member 8 ISO RGD PMID:17285300 RGD:2301914 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
G ACE angiotensin I converting enzyme ISO associated with Hemorrhage;protein:decreased activity:plasma (rat) RGD PMID:3028670 RGD:8142370 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACHE acetylcholinesterase (Yt blood group) IDA RGD PMID:17657467 RGD:5688055 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACTC1 actin alpha cardiac muscle 1 ISO RGD PMID:11680626 RGD:1598729 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,107...34,795,589 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO protein:increased expression:plasma, spleen RGD PMID:23025351 RGD:9681752 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO associated with Obesity RGD PMID:23838384 RGD:8695926 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADIPOR2 adiponectin receptor 2 severity ISO associated with obesity;mRNA:decreased expression:liver (rat) RGD PMID:23838384 RGD:8695926 NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674 		JBrowse link
G ADRA2A adrenoceptor alpha 2A onset ISO mRNA:increased expression:spleen RGD PMID:20302880 RGD:6480487 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO protein:increased expression:kidney RGD PMID:16725227 RGD:6903849 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO protein:decreased expression:kidney RGD PMID:16725227 RGD:6903849 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G AHR aryl hydrocarbon receptor severity ISO RGD PMID:24930766 RGD:39939032 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:22824368 RGD:38676479 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A ISO RGD PMID:16930621 RGD:1599054 NCBI chr16:30,053,151...30,070,414
Ensembl chr16:30,053,090...30,070,420
Ensembl chr16:30,053,090...30,070,420
Ensembl chr16:30,053,090...30,070,420 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A ISO RGD PMID:16930621 RGD:1599054 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:15328337 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G APOA1 apolipoprotein A1 treatment IDA
ISO 		RGD PMID:18593575 PMID:23227448 RGD:7241573, RGD:7241868 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOB apolipoprotein B ISO RGD PMID:16719989 RGD:1599165 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOE apolipoprotein E IDA rat model treated with human protein RGD PMID:9153287 RGD:6904216 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G ASL argininosuccinate lyase ISO RGD PMID:10652239 RGD:1599265 NCBI chr 7:66,075,819...66,093,576
Ensembl chr 7:66,075,800...66,094,697 		JBrowse link
G ASS1 argininosuccinate synthase 1 ISO RGD PMID:10652239 RGD:1599265 NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274 		JBrowse link
G ATF2 activating transcription factor 2 treatment ISO protein:increased expression, increased activity:small intestine mucosa RGD PMID:21641970 PMID:24312512 RGD:5135029, RGD:10047418 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO mRNA:increased expression:diaphragm RGD PMID:23940949 RGD:10054120 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCHE butyrylcholinesterase IDA RGD PMID:17657467 RGD:5688055 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA:decreased expression:diaphragm RGD PMID:23940949 RGD:10054120 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G C5AR1 complement C5a receptor 1 ISO mRNA:increased expression:lung RGD PMID:9272704 RGD:70679 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G CASP1 caspase 1 ISO RGD PMID:17384935 RGD:2315892 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP3 caspase 3 ISO mRNA:increased expression:diaphragm RGD PMID:23940949 RGD:10054120 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 ISO RGD PMID:19168786 RGD:5684539 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:23214195 RGD:10400903 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CBS cystathionine beta-synthase severity ISO mRNA:increased expression:liver (rat)
Protein:increased expression:spleen, lung (mouse) 		RGD PMID:27748832 PMID:16100527 PMID:24702258 PMID:27748832 RGD:40903019, RGD:40903049, RGD:40903035, RGD:40903019 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO protein:increased expression:plasma RGD PMID:19060786 RGD:2307004 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased expression:plasma RGD PMID:16215387 RGD:2307171 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:17016504 RGD:5688178 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CD14 CD14 molecule ISO protein:increased expression:liver, endothelial cell of sinusoid RGD PMID:12046090 RGD:724637 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD40 CD40 molecule ISO protein:decreased nitrosylation:macrophage RGD PMID:20473113 RGD:5490974 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta treatment ISO RGD PMID:15192048 PMID:14659593 RGD:1625687, RGD:40903034 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107 		JBrowse link
G CS citrate synthase ISO protein:increased expression:gastrocnemius RGD PMID:25674200 RGD:329337350 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391 		JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA RGD PMID:9514298 RGD:11039535 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:atrium endocardium RGD PMID:19282612 RGD:4891965 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 ISO mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G EDN1 endothelin 1 ISO mRNA, protein:increased expression:liver (rat) RGD PMID:11206318 RGD:8662297 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EP300 E1A binding protein p300 ISO associated with Kidney Reperfusion Injury; protein:altered localization:kidney (rat) RGD PMID:23936185 RGD:7257563 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:19154430 RGD:5688360 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564 		JBrowse link
G EPO erythropoietin treatment IDA RGD PMID:23214195 RGD:10400903 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G F12 coagulation factor XII ISO RGD PMID:11092686 RGD:7394782 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583 		JBrowse link
G F2 coagulation factor II, thrombin treatment
severity 		ISO
IEP 		associated with liver cirrhosis;protein:increased expression:blood plasma (human)
associated with liver cirrhosis;protein:increased expression:plasma (human) 		RGD PMID:21396682 PMID:10604885 PMID:7615203 PMID:10887118 PMID:9863491 More... RGD:5147765, RGD:40818436, RGD:14974253, RGD:40818427, RGD:14401592, RGD:10449434, RGD:6893482, RGD:5147779 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G F3 coagulation factor III, tissue factor treatment ISO
IMP 		associated with Protein C Deficiency RGD PMID:21396682 PMID:20858853 PMID:8956768 RGD:5147765, RGD:11341685, RGD:11340208 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G F5 coagulation factor V ISO RGD PMID:11092686 RGD:7394782 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588 		JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:11092686 PMID:16378835 RGD:7394782, RGD:11041650 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685 		JBrowse link
G F8 coagulation factor VIII ISO RGD PMID:11092686 RGD:7394782 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940 		JBrowse link
G FAS Fas cell surface death receptor ISO mRNA, protein:increased expression:spleen (rat) RGD PMID:20428798 RGD:8662930 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FGA fibrinogen alpha chain treatment ISO RGD PMID:19295478 RGD:11040925 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FOXP3 forkhead box P3 ISO protein:increased expression:intestinal mucosa RGD PMID:19998507 RGD:38455980 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G GCH1 GTP cyclohydrolase 1 treatment ISO mRNA:increased expression:lung
associated with liver cirrhosis 		RGD PMID:9388472 PMID:16845913 PMID:14647062 RGD:329961576, RGD:401793756, RGD:401700399 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G GFER growth factor, augmenter of liver regeneration ISO RGD PMID:23073658 RGD:9685733 NCBI chr16:1,984,193...1,987,749
Ensembl chr16:1,984,193...1,987,749 		JBrowse link
G GHR growth hormone receptor ISO mRNA:decreased expression:liver RGD PMID:12654216 PMID:12217886 RGD:2307380, RGD:625688 NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878 		JBrowse link
G GPT glutamic--pyruvic transaminase treatment ISO RGD PMID:25514429 RGD:401717525 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GSR glutathione-disulfide reductase treatment ISO RGD PMID:25469663 RGD:10401928 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G HMGB1 high mobility group box 1 ISO protein:increased expression:heart, serum RGD PMID:18503231 RGD:10402065 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO RGD PMID:21396999 RGD:10755715 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSF1 heat shock transcription factor 1 treatment ISO RGD PMID:25571843 RGD:10402404 NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO
EXP 		mRNA, protein:increased expression:medulla oblongata
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:16741687 PMID:16675490 RGD:1624232 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:lung (rat) RGD PMID:19776691 RGD:4145502 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:24930766 PMID:28077574 RGD:39939032, RGD:39939117 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 ISO RGD PMID:24930766 RGD:39939032 NCBI chr 8:39,934,651...40,016,392
Ensembl chr 8:39,934,614...40,016,392 		JBrowse link
G IFNG interferon gamma ISO protein:increased expression:serum: RGD PMID:9195172 RGD:10755747 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1 insulin like growth factor 1 ISO mRNA, protein:decreased expression:liver, serum RGD PMID:18492809 PMID:12217886 RGD:10402757, RGD:625688 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO RGD PMID:12217886 RGD:625688 NCBI chr16:1,790,413...1,794,908
Ensembl chr16:1,790,413...1,794,971 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO RGD PMID:12217886 RGD:625688 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO mRNA, protein:decreased expression:liver, serum RGD PMID:18492809 RGD:10402757 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 ISO RGD PMID:12217886 RGD:625688 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:28664613 PMID:27943364 RGD:14975137, RGD:14975170 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 treatment IDA RGD PMID:10674721 RGD:8549626 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:plasma RGD PMID:9636192 PMID:22426124 RGD:6907109, RGD:7794786 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:plasma RGD PMID:17201737 RGD:1626625 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO
IDA 		mRNA:increased expression:lung, spleen, liver (rat) RGD PMID:1385928 PMID:8855299 RGD:8551846, RGD:11522760 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL32 interleukin 32 ameliorates IMP human gene in a mouse model RGD PMID:24743568 RGD:150340731 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192 		JBrowse link
G IL6 interleukin 6 ISO associated with Diabetes Mellitus, Experimental; Protein:increased expression:extracellular space (rat)
protein:increased expression:serum (rat) 		RGD PMID:19449282 PMID:22227956 PMID:21396682 RGD:2307179, RGD:6893482, RGD:5147765 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 IEP mRNA, protein:increased expression:blood (human) RGD PMID:17982103 RGD:36049802 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRS1 insulin receptor substrate 1 ISO protein:increased tyrosine nitration, decreased tyrosine phosphorylation:skeletal muscle RGD PMID:21206533 RGD:6483008 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G ITGA2B integrin subunit alpha 2b ISO RGD PMID:15280099 RGD:2316360 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO RGD PMID:15280099 RGD:2316360 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO RGD PMID:22609006 RGD:6892951 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G LBP lipopolysaccharide binding protein treatment ISO
IMP 		mRNA:increased expression:hepatocyte RGD PMID:8418776 PMID:8593028 PMID:16307218 RGD:9685191, RGD:9685196, RGD:9685193 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LCN2 lipocalin 2 ISO mRNA:increased expression:brain,liver RGD PMID:21943033 RGD:126779582 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G MAP2 microtubule associated protein 2 ISO mRNA, protein:decreased expression:neuron RGD PMID:21421895 RGD:6483086 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 treatment ISO protein:increased activity:small intestine mucosa RGD PMID:21641970 PMID:24312512 RGD:5135029, RGD:10047418 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO protein:increased phophorylation:hippocampus (rat) RGD PMID:12207162 RGD:150340687 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MC4R melanocortin 4 receptor ISO mRNA:increased expression:paraventricular nucleus (rat) RGD PMID:21343543 RGD:6484214 NCBI chr18:60,371,062...60,372,775
Ensembl chr18:60,371,062...60,372,775 		JBrowse link
G MIF macrophage migration inhibitory factor ISO protein:increased expression:plasma RGD PMID:16601957 RGD:1641983 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR146A microRNA 146a treatment ISO miRNA:increased expression:spleen (mouse) RGD PMID:30867482 RGD:34888227 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MIR155 microRNA 155 treatment ISO associated with familial hyperlipidemia RGD PMID:28970282 PMID:28264607 PMID:29079998 PMID:29979224 RGD:21079445, RGD:24922204, RGD:21081539, RGD:21081538 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MME membrane metalloendopeptidase severity ISO RGD PMID:11078421 RGD:13801040 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G MMP3 matrix metallopeptidase 3 ISO RGD PMID:17083784 RGD:2290426 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MT2A metallothionein 2A ISO mRNA:increased expression:liver (rat) RGD PMID:22100509 RGD:6483852 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MT3 metallothionein 3 ISO RGD PMID:12135776 RGD:10412330 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming ISO RGD PMID:19099858 RGD:7349370 NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511 		JBrowse link
G MYH6 myosin heavy chain 6 ISO RGD PMID:7874842 RGD:12792976 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273 		JBrowse link
G MYH7 myosin heavy chain 7 ISO RGD PMID:7874842 RGD:12792976 NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:26646455 RGD:42722616 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha exacerbates
treatment 		ISO RGD PMID:19098124 PMID:10229101 RGD:126908017, RGD:126928139 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO
EXP 		mRNA, protein:increased expression:intestine
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:12620498 PMID:16787348 PMID:20519137 RGD:4891470, RGD:5147779 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO protein:increased expression:aorta (rat) RGD PMID:10462376 RGD:7794732 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NPY neuropeptide Y treatment ISO RGD PMID:15342191 RGD:1580787 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:15640646 RGD:4892561 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G OTC ornithine transcarbamylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr  X:38,327,684...38,422,928
Ensembl chr  X:38,327,598...38,422,908 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 ISO RGD PMID:19268478 PMID:12217886 RGD:10427879, RGD:625688 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial ISO mRNA,protein:decreased expression,decreased activity:liver: RGD PMID:19268478 RGD:10427879 NCBI chr14:24,094,171...24,104,125
Ensembl chr14:24,094,053...24,110,598 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO RGD PMID:16337011 RGD:6483567 NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO RGD PMID:16337011 RGD:6483567 NCBI chr20:17,226,107...17,484,578
Ensembl chr20:17,226,107...17,484,578 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22119535 RGD:6771174 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PF4 platelet factor 4 treatment ISO RGD PMID:20601223 RGD:329901905 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G PGF placental growth factor ISO protein:increased expression:multiple RGD PMID:16702604 RGD:6483601 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PLA2G7 phospholipase A2 group VII ISO protein:increased expression: : RGD PMID:10748027 RGD:7248791 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693 		JBrowse link
G PLAT plasminogen activator, tissue type treatment IDA RGD PMID:9091588 RGD:11541073 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO protein:increased expression:small intestine mucosa RGD PMID:21641970 RGD:5135029 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO mRNA:decreased expression:epididymal fat pad RGD PMID:20421294 RGD:6484543 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO protein:increased expression:liver, mitochondrion (mouse) RGD PMID:28615325 RGD:13432559 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment IDA RGD PMID:18205901 PMID:23170801 RGD:11100030, RGD:11100034 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242 		JBrowse link
G PTAFR platelet activating factor receptor treatment ISO RGD PMID:2178565 RGD:10041063 NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO protein:increased expression:paraventricular hypothalamic nucleus parvicellular division (rat) RGD PMID:11058222 RGD:10043329 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735 		JBrowse link
G PTGIS prostaglandin I2 synthase treatment ISO RGD PMID:11076704 RGD:401960076 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:21641970 RGD:5135029 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G REN renin ISO protein:increased activity:blood plasma (mouse)
protein:increased activity:blood plasma (rat) 		RGD PMID:30027346 PMID:16512638 RGD:125097481, RGD:125097499 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G SERPINC1 serpin family C member 1 treatment IDA
ISO 		RGD PMID:16457847 PMID:21396682 PMID:20519137 PMID:15995859 RGD:1599326, RGD:5147765, RGD:5147779, RGD:1599332 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327 		JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO RGD PMID:21396682 PMID:25396762 RGD:5147765, RGD:10449434 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SERPINF1 serpin family F member 1 IEP protein:increased expression:plasma (human) RGD PMID:12386642 RGD:36174005 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G SERPING1 serpin family G member 1 treatment IDA RGD PMID:18652771 RGD:8661643 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO protein:decreased expression:parietal cortex RGD PMID:17306796 RGD:5686693 NCBI chr10:49,610,310...49,612,720
Ensembl chr10:49,610,310...49,612,720 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 treatment ISO RGD PMID:18313662 RGD:7243881 NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 treatment ISO RGD PMID:18313662 RGD:7243881 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638 		JBrowse link
G SLC38A3 solute carrier family 38 member 3 ISO RGD PMID:20036385 RGD:9999227 NCBI chr 3:50,205,271...50,221,486
Ensembl chr 3:50,205,246...50,221,486 		JBrowse link
G SLC38A5 solute carrier family 38 member 5 ISO RGD PMID:20036385 RGD:9999227 NCBI chr  X:48,458,544...48,470,260
Ensembl chr  X:48,458,537...48,470,260 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 ISO RGD PMID:26337286 RGD:151361133 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
G SLPI secretory leukocyte peptidase inhibitor ISO RGD PMID:25466948 RGD:9999425 NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO mRNA:increased expression:liver, skeletal muscle RGD PMID:15169905 RGD:2298923 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO mRNA:increased expression:liver, skeletal muscle RGD PMID:15169905 PMID:12217886 RGD:2298923, RGD:625688 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA, protein:decreased expression:kidney RGD PMID:10703670 RGD:2300026 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B ISO protein:decreased tyrosine phosphorylation:liver RGD PMID:17327369 RGD:1601383 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633 		JBrowse link
G TBXA2R thromboxane A2 receptor ISO RGD PMID:15647606 PMID:2580129 RGD:1601450, RGD:11059531 NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO RGD PMID:15647606 RGD:1601450 NCBI chr 7:139,778,242...140,020,293
Ensembl chr 7:139,777,051...140,020,325 		JBrowse link
G TDO2 tryptophan 2,3-dioxygenase severity ISO RGD PMID:24930766 RGD:39939032 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406 		JBrowse link
G TFPI tissue factor pathway inhibitor treatment IDA RGD PMID:17537762 RGD:11062086 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G THBD thrombomodulin ISO
IDA 		mRNA:decreased expression:endothelial cell RGD PMID:12611420 PMID:20348393 PMID:19487933 RGD:1601652, RGD:5685037, RGD:5684988 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:17083784 RGD:2290426 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041 		JBrowse link
G TLR2 toll like receptor 2 treatment ISO
IEP 		associated with liver cirrhosis RGD PMID:22172266 PMID:12610323 RGD:7241094, RGD:597538466 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 treatment
disease_progression 		ISO mRNA:increased expression:liver: RGD PMID:22172266 PMID:23977376 PMID:23977376 RGD:7241094, RGD:14697731, RGD:14697731 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor treatment ISO protein:increased expression:plasma
XCO:0000822 JTE-607
associated with liver cirrhosis
protein:increased expression:plasma (rat) 		RGD PMID:17324147 PMID:10493164 PMID:15242491 PMID:18078960 PMID:8283134 More... RGD:4891465, RGD:40903016, RGD:38501090, RGD:15023464, RGD:14995443, RGD:14995427, RGD:5147765, RGD:5147779 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 treatment ISO
IEP 		RGD PMID:21507332 PMID:15585833 RGD:126925982, RGD:126928122 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,100...41,286,682 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO mRNA:increased expression:brain: RGD PMID:20061033 RGD:7240511 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VWF von Willebrand factor ISO protein:increased expression:endothelial cell: RGD PMID:2650559 RGD:11079230 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770 		JBrowse link
endotoxin shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCH1 GTP cyclohydrolase 1 treatment ISO RGD PMID:8602831 RGD:329961578 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A treatment ISO RGD PMID:19318092 RGD:401901206 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076 		JBrowse link
Fungemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule treatment ISO RGD PMID:23663657 RGD:40818234 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G PDCD1 programmed cell death 1 treatment ISO protein:increased expression:CD4 Tcell, CD8 Tcell: RGD PMID:23663657 PMID:23663657 RGD:40818234, RGD:40818234 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 treatment
susceptibility 		IAGP
IDA 		DNA:SNP: :c3435C>T(human)
DNA:hypermethylation:promoter
DNA:SNPs,haplotype: :rs2032582, rs1128503 (human)
DNA:haplotype: :1236C>T, 2677G>T,3435C>T (human) 		RGD PMID:28934955 PMID:19331170 PMID:28422980 PMID:17015054 RGD:39456120, RGD:39457680, RGD:39457679, RGD:39456123 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ACE angiotensin I converting enzyme severity ISO RGD PMID:31234939 RGD:39939120 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACKR1 atypical chemokine receptor 1 (Duffy blood group) IAGP
EXP 		ClinVar Annotator: match by term: Plasmodium vivax, resistance to
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM		 PMID:7663520 PMID:8547665 PMID:8651934 PMID:10570183 PMID:10791881 More... NCBI chr 1:159,204,875...159,206,500
Ensembl chr 1:159,204,875...159,206,500 		JBrowse link
G AICDA activation induced cytidine deaminase ISO protein:increased expression: B cell RGD PMID:27980783 RGD:30310233 NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242 		JBrowse link
G ANK1 ankyrin 1 ISS OMIM:609148 | OMIM:611162 MouseDO NCBI chr 8:41,653,225...41,896,741
Ensembl chr 8:41,653,220...41,896,741 		JBrowse link
G APOE apolipoprotein E IAGP DNA:missense mutations:cds:p.C112R, p.C158R (human) RGD PMID:24116184 RGD:11039486 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G AQP4 aquaporin 4 ISS OMIM:609148 | OMIM:611162 MouseDO NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771 		JBrowse link
G CBS cystathionine beta-synthase susceptibility IAGP DNA:insertion:cds: (844ins68) (human) RGD PMID:27198213 RGD:40903062 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CD163 CD163 molecule exacerbates
severity 		IEP protein:increased expression:blood plasma (human)
protein:altered expression:blood plasma (human) 		RGD PMID:22290142 PMID:18632918 RGD:127285797, RGD:149735529 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893 		JBrowse link
G CD1D CD1d molecule ameliorates
exacerbates 		ISO RGD PMID:12938235 PMID:24703850 RGD:127345117, RGD:127345121 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) IAGP
EXP 		ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to
ClinVar Annotator: match by term: Malaria, susceptibility to
CTD Direct Evidence: marker/mechanism 		ClinVar
OMIM
CTD		 PMID:10890433 PMID:18305138 PMID:19403559 PMID:25741868 PMID:28960434 More... NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD40 CD40 molecule severity ISO RGD PMID:11485931 RGD:11352239 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand severity ISO RGD PMID:11485931 RGD:11352239 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CISH cytokine inducible SH2 containing protein susceptibility IAGP
EXP 		ClinVar Annotator: match by term: Malaria, susceptibility to
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM		 PMID:20484391 NCBI chr 3:50,606,489...50,611,774
Ensembl chr 3:50,606,489...50,611,774 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) IAGP
EXP 		ClinVar Annotator: match by term: CR1-related condition | ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar Annotator: match by term: Malaria, severe, resistance to
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD		 PMID:10528197 PMID:14694201 PMID:20855594 PMID:25741868 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765 		JBrowse link
G CRP C-reactive protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:8730300 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 treatment
disease_progression 		ISO
IEP 		RGD PMID:28892065 PMID:28892065 RGD:38455986, RGD:38455986 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G EPHB2 EPH receptor B2 ISO mRNA:increased expression:liver RGD PMID:25784101 RGD:127285023 NCBI chr 1:22,710,838...22,921,500
Ensembl chr 1:22,710,839...22,921,500 		JBrowse link
G EPHB3 EPH receptor B3 ISO RGD PMID:25784101 RGD:127285023 NCBI chr 3:184,561,785...184,582,408
Ensembl chr 3:184,561,785...184,582,408 		JBrowse link
G EPHB6 EPH receptor B6 ISO RGD PMID:25784101 RGD:127285023 NCBI chr 7:142,855,076...142,871,093
Ensembl chr 7:142,855,061...142,871,094 		JBrowse link
G FCGR2A Fc gamma receptor IIa susceptibility IAGP
EXP 		DNA:missense mutation:cds:p.H131R (human)
ClinVar Annotator: match by term: Malaria, severe, susceptibility to
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM
RGD		 PMID:8636449 PMID:9843982 PMID:10675363 PMID:15367919 PMID:19915573 More... RGD:5147921 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G FCGR2B Fc gamma receptor IIb IAGP
ISS
EXP 		ClinVar Annotator: match by term: Malaria, resistance to
CTD Direct Evidence: marker/mechanism 		ClinVar
OMIM
MouseDO
CTD		 PMID:12115230 PMID:15459183 PMID:16115811 PMID:16170323 PMID:17435165 More... NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FOXP3 forkhead box P3 disease_progression IEP RGD PMID:19338000 PMID:16169501 RGD:38455985, RGD:38455992 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase susceptibility
severity 		IAGP
EXP 		DNA:SNPs: :multiple
ClinVar Annotator: match by term: Malaria, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:point mutation:cds:c.968T>C (human) 		ClinVar
CTD
OMIM
RGD		 PMID:5448 PMID:16832 PMID:511159 PMID:736032 PMID:853376 More... RGD:10449111, RGD:10449115 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GYPA glycophorin A (MNS blood group) IAGP
EXP 		CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr 4:144,109,303...144,140,718
Ensembl chr 4:144,109,303...144,140,751 		JBrowse link
G GYPB glycophorin B (MNS blood group) IAGP
EXP 		CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr 4:143,995,188...144,019,380
Ensembl chr 4:143,996,104...144,019,380 		JBrowse link
G GYPC glycophorin C (Gerbich blood group) IAGP
EXP 		ClinVar Annotator: match by term: Malaria, resistance to
ClinVar Annotator: match by term: GYPC-related condition
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM		 PMID:1991173 PMID:5011657 PMID:8157284 PMID:11719395 PMID:12469115 More... NCBI chr 2:126,656,158...126,696,667
Ensembl chr 2:126,656,133...126,696,667 		JBrowse link
G HBB hemoglobin subunit beta resistance IAGP
EXP 		Hemoglobin C; DNA:polymorphism:CDS:69G>A, amino acid E6K
ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar Annotator: match by term: Malaria, resistance to
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM
RGD		 PMID:14973 PMID:81926 PMID:88735 PMID:750553 PMID:893136 More... RGD:1600894 NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395 		JBrowse link
G HMOX1 heme oxygenase 1 ISS OMIM:609148 | OMIM:611162 MouseDO NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HP haptoglobin EXP CTD Direct Evidence: marker/mechanism CTD PMID:8730300 PMID:16597321 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 susceptibility IAGP
ISS
EXP 		ClinVar Annotator: match by term: ICAM1-related condition
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to
ClinVar Annotator: match by term: Malaria, susceptibility to
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
MouseDO
CTD		 PMID:9259284 PMID:9861406 PMID:10417733 PMID:10699175 PMID:23609612 More... NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNG interferon gamma ISS OMIM:609148 | OMIM:611162 MouseDO NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma IAGP ClinVar Annotator: match by term: Malaria, susceptibility to ClinVar PMID:1945893 PMID:3198117 PMID:6805883 PMID:7803800 PMID:8244337 More... NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 ISO RGD PMID:28359899 RGD:39938859 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL21 interleukin 21 exacerbates ISO RGD PMID:25763578 RGD:127285358 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL27 interleukin 27 ameliorates ISO RGD PMID:24522137 PMID:26968425 RGD:126790512, RGD:11530371 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL33 interleukin 33 ISO protein:increased expression:serum: RGD PMID:28359899 RGD:39938859 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G KIR3DL1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 severity IAGP DNA:deletion:cds RGD PMID:21889618 RGD:38676475 NCBI chr19:54,816,468...54,830,778
Ensembl chr19:54,816,468...54,830,778 		JBrowse link
G KIR3DS1 killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 exacerbates IAGP DNA:deletion: (human) RGD PMID:21889618 RGD:38676475
G LIMASI lncRNA inflammatory and mucous response associated, antisense to ICAM1 IAGP ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to 		ClinVar PMID:9259284 PMID:9861406 PMID:10417733 PMID:10699175 PMID:23609612 More... NCBI chr19:10,260,010...10,283,450 JBrowse link
G LOC106099062 HBB recombination region IAGP ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar Annotator: match by term: Malaria, resistance to 		ClinVar PMID:81926 PMID:88735 PMID:909565 PMID:1301203 PMID:1353069 More... NCBI chr11:5,226,570...5,228,834 JBrowse link
G LOC107133510 origin of replication at HBB IAGP ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar Annotator: match by term: Malaria, resistance to 		ClinVar PMID:14973 PMID:81926 PMID:88735 PMID:750553 PMID:893136 More... NCBI chr11:5,222,166...5,229,620 JBrowse link
G LOC107181288 origin of replication in promoter of G6PD IAGP ClinVar Annotator: match by term: Malaria, susceptibility to ClinVar PMID:38592584 NCBI chr  X:154,546,511...154,547,759 JBrowse link
G LOC110006319 beta-globin gene 3' regulatory region IAGP ClinVar Annotator: match by term: Malaria, susceptibility to ClinVar PMID:14973 PMID:750553 PMID:893136 PMID:1112610 PMID:1177278 More... NCBI chr11:5,223,780...5,226,590 JBrowse link
G LOC111365141 NOS2 5' regulatory region IAGP ClinVar Annotator: match by term: Malaria, resistance to ClinVar PMID:12433515 NCBI chr17:27,800,158...27,817,264 JBrowse link
G LOC129929052 ATAC-STARR-seq lymphoblastoid silent region 21114 IAGP ClinVar Annotator: match by term: Malaria, susceptibility to ClinVar PMID:38592584 NCBI chr  X:154,546,728...154,547,287 JBrowse link
G LOC129936806 ATAC-STARR-seq lymphoblastoid silent region 14400 IAGP ClinVar Annotator: match by term: Malaria, susceptibility to ClinVar PMID:20484391 NCBI chr 3:50,611,643...50,612,122 JBrowse link
G LTBR lymphotoxin beta receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:15788153 NCBI chr12:6,375,160...6,391,566
Ensembl chr12:6,375,045...6,391,571 		JBrowse link
G MAPKAPK3 MAPK activated protein kinase 3 IAGP ClinVar Annotator: match by term: Malaria, susceptibility to ClinVar PMID:20484391 NCBI chr 3:50,611,520...50,649,291
Ensembl chr 3:50,611,520...50,649,291 		JBrowse link
G MIR122 microRNA 122 treatment ISO RGD PMID:28123381 RGD:35673288 NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158 		JBrowse link
G MIR142 microRNA 142 treatment ISO RGD PMID:28123381 RGD:35673288 NCBI chr17:58,331,232...58,331,318
Ensembl chr17:58,331,232...58,331,318 		JBrowse link
G MIRLET7A1 microRNA let-7a-1 treatment ISO RGD PMID:28123381 RGD:35673288 NCBI chr 9:94,175,957...94,176,036
Ensembl chr 9:94,175,957...94,176,036 		JBrowse link
G MIRLET7C microRNA let-7c treatment ISO RGD PMID:28123381 RGD:35673288 NCBI chr21:16,539,828...16,539,911
Ensembl chr21:16,539,828...16,539,911 		JBrowse link
G MKI67 marker of proliferation Ki-67 ISO associated with Lung Neoplasms RGD PMID:21931708 RGD:6483517 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 susceptibility IAGP
EXP 		ClinVar Annotator: match by term: Malaria, severe, susceptibility to
ClinVar Annotator: match by term: Malaria, severe, susceptibility to | ClinVar Annotator: match by term: NCR3-related condition
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM		 PMID:17208487 NCBI chr 6:31,588,895...31,593,006
Ensembl chr 6:31,588,895...31,593,006 		JBrowse link
G NOS2 nitric oxide synthase 2 IAGP
EXP 		ClinVar Annotator: match by term: Malaria, resistance to
ClinVar Annotator: match by term: NOS2-related condition
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar Annotator: match by term: Malaria, severe, resistance to 		ClinVar
CTD
OMIM		 PMID:9457101 PMID:12433515 PMID:25741868 PMID:28492532 PMID:31995689 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PKLR pyruvate kinase L/R susceptibility IAGP
ISS
ISO 		DNA:mutations, haplotype:multiple (human)
OMIM:609148 | OMIM:611162
DNA:missense mutation:cds:p.I90N (mouse) 		MouseDO
RGD		 PMID:20377593 PMID:14595440 RGD:11535999, RGD:11537407 NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438 		JBrowse link
G PRF1 perforin 1 ISO RGD PMID:21525386 RGD:6482803 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759 		JBrowse link
G PROCR protein C receptor disease_progression IEP RGD PMID:27671831 RGD:126848795 NCBI chr20:35,171,096...35,216,259
Ensembl chr20:35,172,072...35,216,240 		JBrowse link
G SCN8A sodium voltage-gated channel alpha subunit 8 IAGP ClinVar Annotator: match by term: Malaria, susceptibility to ClinVar PMID:25741868 NCBI chr12:51,591,233...51,812,864
Ensembl chr12:51,590,266...51,812,864 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 IAGP DNA:SNP::g.80G>A (human) RGD PMID:27198213 RGD:40903062 NCBI chr21:45,502,517...45,563,025
Ensembl chr21:45,493,572...45,573,365 		JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) EXP
IAGP 		CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malaria, susceptibility to
ClinVar Annotator: match by term: Malaria, cerebral, resistance to 		CTD
ClinVar		 PMID:1378323 PMID:1722314 PMID:1737855 PMID:2146504 PMID:4116984 More... NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:16552072 RGD:1581333 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G TBX21 T-box transcription factor 21 IEP RGD PMID:19338000 RGD:38455985 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
G TIRAP TIR domain containing adaptor protein EXP
IAGP 		CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malaria, resistance to 		CTD
OMIM
ClinVar		 PMID:16991088 PMID:17322885 PMID:18305471 PMID:25741868 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TNF tumor necrosis factor susceptibility IAGP
EXP 		DNA:polymorphism:promoter:-376G>A
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD
RGD		 PMID:8056188 PMID:9818939 PMID:10369255 PMID:10450718 PMID:11261930 More... RGD:1624967 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 severity IEP
IAGP 		DNA:SNP: :rs2234237A>T (human) RGD PMID:27671831 PMID:27671831 RGD:126848795, RGD:126848795 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,100...41,286,682 		JBrowse link
G TSLP thymic stromal lymphopoietin ISO mRNA:altered expression:multiple (mouse) RGD PMID:28955823 RGD:38596344 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026 		JBrowse link
Malarial Anemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCGR3A Fc gamma receptor IIIa severity
susceptibility 		IEP
IAGP 		DNA:polymorphism: :p.F176V (human) RGD PMID:20231419 PMID:23045477 RGD:11040771, RGD:11344971 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) severity IAGP DNA:snp:promoter:g.-5699T>C (human) RGD PMID:16960783 RGD:10450507 NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141 		JBrowse link
G TLR9 toll like receptor 9 susceptibility IAGP DNA:SNP:promoter:g.-1237T>C (rs5743836) (human) RGD PMID:23045477 RGD:11344971 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
Neonatal Sepsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMP cathelicidin antimicrobial peptide ameliorates IDA RGD PMID:15645239 RGD:458925287 NCBI chr 3:48,223,495...48,225,485
Ensembl chr 3:48,223,347...48,225,491 		JBrowse link
G CRP C-reactive protein treatment ISO RGD PMID:15645239 RGD:458925287 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G IL27 interleukin 27 ISO
IEP 		protein:increased expression:blood serum (mouse)
protien:increased expression:blood serum (human) 		RGD PMID:31818960 PMID:22766719 RGD:126790524, RGD:126790543 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G PLA2G2A phospholipase A2 group IIA susceptibility IAGP DNA:SNP:enhancer: (rs1891320) (human) RGD PMID:20463618 RGD:6482720 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
Plasmodium falciparum malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility IAGP DNA:SNPs,haplotype:multiple RGD PMID:18003641 RGD:39938831 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024 		JBrowse link
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 IEP protein:decreased activity:plasma (human) RGD PMID:20062916 RGD:10449041 NCBI chr 9:133,414,337...133,459,386
Ensembl chr 9:133,414,358...133,459,402 		JBrowse link
G BSG basigin (Ok blood group) EXP CTD Direct Evidence: therapeutic CTD PMID:22080952 PMID:26195724 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494 		JBrowse link
G CAST calpastatin IEP protein:alter localization:erythrocyte RGD PMID:17359359 RGD:5509812 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595
Ensembl chr 5:96,247,756...96,779,595 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 IEP mRNA, protein:increased expression:blood, RGD PMID:15972509 RGD:5683898 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CLEC11A C-type lectin domain containing 11A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19884328 NCBI chr19:50,723,364...50,725,708
Ensembl chr19:50,723,364...50,725,708 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:9230440 PMID:11724985 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 treatment IAGP DNA:polymorphisms:: RGD PMID:10471063 RGD:124713538 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G FAS Fas cell surface death receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625619 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FCGR2A Fc gamma receptor IIa severity IAGP DNA:missense mutation:cds:p.R131H (rs1801274) (human) RGD PMID:18194515 RGD:5147927 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase severity IAGP DNA:missense mutation:cds:202G>A (p.V68M) (human) RGD PMID:24943486 RGD:10449113 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 severity IAGP RGD PMID:19635899 RGD:10450848 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HBB hemoglobin subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:20305663 NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP DNA:polymorphism:cds:HLA-DQB1*0501 (human) RGD PMID:11076705 RGD:11041780 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HP haptoglobin severity IAGP DNA:missense mutation:cds:p.K54E (human) RGD PMID:24478401 RGD:11041793 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G IL13 interleukin 13 IEP protein:increased expression:plasma RGD PMID:21985368 RGD:5684362 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP DNA:haplotype:exon: RGD PMID:18396436 RGD:11530064 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G TNF tumor necrosis factor severity IEP protein:increased expression:plasma RGD PMID:1984482 RGD:10450571 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Plasmodium vivax malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACKR1 atypical chemokine receptor 1 (Duffy blood group) IAGP ClinVar Annotator: match by term: ACKR1-related condition
ClinVar Annotator: match by term: Resistance to Plasmodium vivax infection 		OMIM
ClinVar		 PMID:7663520 PMID:7669660 PMID:7705836 PMID:8547665 PMID:8651934 More... NCBI chr 1:159,204,875...159,206,500
Ensembl chr 1:159,204,875...159,206,500 		JBrowse link
Pregnancy-associated Malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 IEP RGD PMID:24717969 RGD:11041890 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G MIR146A microRNA 146a susceptibility IAGP miRNA:SNP: (rs2910164) (human) RGD PMID:30642347 RGD:126925184 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
toxic shock syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin treatment ISO RGD PMID:2424486 RGD:10046036 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229 		JBrowse link
G ACE angiotensin I converting enzyme severity IAGP DNA:SNP, insertion/deletion:promoter, intron: (rs4291, rs4646994) RGD PMID:28336767 RGD:39939121 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ADK adenosine kinase ISO RGD PMID:8207212 RGD:6482670 NCBI chr10:74,151,221...74,709,290
Ensembl chr10:74,151,202...74,709,963 		JBrowse link
G ADM adrenomedullin ISO RGD PMID:17318497 PMID:17766482 RGD:1625310, RGD:1642599 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADRB2 adrenoceptor beta 2 disease_progression
treatment 		IAGP
IDA 		DNA:polymorphism: :rs1042717(human) RGD PMID:19850944 PMID:16076286 RGD:8548487, RGD:8548529 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO RGD PMID:21270403 RGD:6767566 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:24028651 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517 		JBrowse link
G C5AR1 complement C5a receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18063050 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G CCKBR cholecystokinin B receptor ISO mRNA:increased expression:myocardium RGD PMID:15948246 RGD:2311332 NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 disease_progression IEP RGD PMID:28834779 RGD:14995949 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CD274 CD274 molecule severity IEP protein:increased expression:serum
protein:increased expression:lymphocyte, mononcyte 		RGD PMID:29702526 PMID:26063974 RGD:40822808, RGD:41410786 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G ELANE elastase, neutrophil expressed treatment ISO RGD PMID:18323746 RGD:10450579 NCBI chr19:852,303...856,243
Ensembl chr19:851,014...856,247 		JBrowse link
G ENO2 enolase 2 ISO proteiin:increased expression:serum RGD PMID:17083782 RGD:2293748 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G F2 coagulation factor II, thrombin severity IEP protein:decreased expression:blood plasma (human) RGD PMID:2788582 RGD:40822807 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FANCC FA complementation group C ISO RGD PMID:17404312 RGD:11045879 NCBI chr 9:95,099,054...95,317,709
Ensembl chr 9:95,099,054...95,426,796 		JBrowse link
G GC GC vitamin D binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:17852808 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 IEP mRNA:decreased expression:polymorphonuclear leukocyte RGD PMID:24465168 RGD:126848796 NCBI chr11:67,266,473...67,286,556
Ensembl chr11:67,266,473...67,286,556 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha disease_progression IEP
EXP 		associated with Burns
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:28771573 PMID:17568330 PMID:15644645 RGD:5490160, RGD:5490203 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 IEP mRNA:decreased expression:blood RGD PMID:15644645 RGD:5490203 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:18208666 RGD:4145362 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B susceptibility IAGP associated wit community-acquired pneumonia;DNA:SNP: :1267A>G (human) RGD PMID:12771604 RGD:5147601 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 severity IEP protein:increased activity, increased expression:plasma, heart (human) RGD PMID:21765346 RGD:39939075 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IFNG interferon gamma IEP protein:increased expression:plasma RGD PMID:25403265 RGD:38455982 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL10 interleukin 10 severity
onset 		IDA
ISO
IEP 		protein:increased expression:lung (mouse)
protein:increased expression:plasma 		RGD PMID:12117955 PMID:12117955 PMID:28659355 PMID:25403265 PMID:7593621 RGD:1598471, RGD:1598471, RGD:40890272, RGD:38455982, RGD:11049456 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL19 interleukin 19 IEP protein:increased expression:serum RGD PMID:18246602 RGD:5037232 NCBI chr 1:206,770,773...206,842,981
Ensembl chr 1:206,770,764...206,842,981 		JBrowse link
G IL1B interleukin 1 beta severity ISO protein:increased expression:lung (mouse) RGD PMID:28659355 RGD:40890272 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment
susceptibility 		IMP
IAGP 		human gene in a mouse model
associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:polymorphism:: 		RGD PMID:15516267 PMID:23014359 RGD:8551736, RGD:11522756 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL20RA interleukin 20 receptor subunit alpha ISO mRNA:increased expression:multiple RGD PMID:18246602 RGD:5037232 NCBI chr 6:136,999,971...137,044,965
Ensembl chr 6:136,999,971...137,045,180 		JBrowse link
G IL20RB interleukin 20 receptor subunit beta ISO mRNA:increased expression:multiple RGD PMID:18246602 RGD:5037232 NCBI chr 3:136,957,983...137,011,085
Ensembl chr 3:136,946,230...137,011,085 		JBrowse link
G IL27 interleukin 27 ISO protein, mRNA:increased expression:blood serum, spleen (mouse) RGD PMID:20435892 RGD:126790535 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL6 interleukin 6 treatment ISO RGD PMID:2124237 RGD:11060276 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP associated with acute pyelonephritis;DNA:SNPs, missense mutations, haplotypes:promoter, cds:multiple RGD PMID:17202308 RGD:6903268 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MC2R melanocortin 2 receptor ISO protein:increased expression:liver (rat) RGD PMID:2822467 RGD:6484558 NCBI chr18:13,882,044...13,915,707
Ensembl chr18:13,882,044...13,915,707 		JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:17381395 PMID:17565848 RGD:4891013, RGD:1641978 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR155 microRNA 155 IEP RGD PMID:29979224 RGD:21081538 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR21 microRNA 21 exacerbates
ameliorates 		ISO RGD PMID:28437377 PMID:31189875 RGD:41404641, RGD:41404698 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR494 microRNA 494 severity IEP RGD PMID:30783439 RGD:150527846 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 susceptibility IAGP associated with Burns; DNA:missense mutation:cds:m.4216T>C (human) RGD PMID:19487983 RGD:5148017 NCBI chr MT:3,307...4,262
Ensembl chr MT:3,307...4,262 		JBrowse link
G NFKBIA NFKB inhibitor alpha treatment ISO RGD PMID:11961112 RGD:126928137 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:8745224 PMID:16601845 RGD:1580268 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NPPC natriuretic peptide C IEP protein:increased expression:plasma RGD PMID:8117275 RGD:1642297 NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO RGD PMID:15677345 RGD:8657146 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:12445868 RGD:10414070 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDCD1 programmed cell death 1 severity IEP protein:increased expression:serum
protein:increased expression:lymphocyte, mononcyte 		RGD PMID:29702526 PMID:26063974 RGD:40822808, RGD:41410786 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta severity ISO RGD PMID:28659355 RGD:40890272 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO RGD PMID:20693875 RGD:6484122 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment ISO
IDA 		RGD PMID:19320827 PMID:21850534 RGD:11100015, RGD:11100041 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242 		JBrowse link
G PTX3 pentraxin 3 IEP protein:increased expression:plasma (human) RGD PMID:30687307 RGD:38508896 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633 		JBrowse link
G REN renin exacerbates IEP protein:increased activity:blood plasma (human) RGD PMID:31723628 RGD:125097502 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G SELL selectin L ISO protein:increased expression:plasma RGD PMID:19375498 RGD:5685700 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702 		JBrowse link
G SERPINC1 serpin family C member 1 treatment IDA RGD PMID:16732381 RGD:1599323 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327 		JBrowse link
G SERPINE1 serpin family E member 1 susceptibility IAGP associated with Pneumonia; DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:20429897 RGD:4144828 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SERPINF1 serpin family F member 1 severity IEP protein:decreased expression:plasma (human) RGD PMID:6158114 RGD:36174004 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G SERPING1 serpin family G member 1 treatment IDA RGD PMID:8172580 RGD:8661646 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171 		JBrowse link
G SFTPB surfactant protein B IAGP associated with Pneumonia;DNA:polymorphism: :1580C>T (human) RGD PMID:15190959 RGD:4143404 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 severity ISO RGD PMID:19469017 RGD:150573701 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G TBXA2R thromboxane A2 receptor treatment ISO RGD PMID:7816742 RGD:11059599 NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875 		JBrowse link
G TFPI tissue factor pathway inhibitor treatment IDA RGD PMID:11776329 RGD:11062085 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G THPO thrombopoietin IEP protein:increased expression:serum: RGD PMID:20467749 RGD:10449021 NCBI chr 3:184,371,935...184,379,688
Ensembl chr 3:184,371,935...184,381,968 		JBrowse link
G TNF tumor necrosis factor treatment ISO
EXP 		protein:increased expression:peritoneal macrophage, cell surface (rat)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:20054000 PMID:2213560 PMID:12622907 RGD:10449465, RGD:1598936 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 IEP mRNA:decreased expression:polymorphonuclear leukocyte RGD PMID:24465168 RGD:126848796 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,100...41,286,682 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A ISO RGD PMID:23422584 RGD:39938961 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377 		JBrowse link
Viremia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BST2 bone marrow stromal cell antigen 2 IDA associated with Retroviridae Infections; RGD PMID:28381565 RGD:14398820 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630 		JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: therapeutic CTD PMID:11132533 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta IEP RGD PMID:29307521 RGD:42724467 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 151455
    syndrome 39471
      Systemic Inflammatory Response Syndrome 637
        Sepsis 626
          Fungemia + 12
          Neonatal Sepsis 4
          Parasitemia + 234
          Viremia + 3
          bacterial sepsis + 212
          toxic shock syndrome 62
Path 2
Term Annotations click to browse term
  disease 151455
    Pathological Conditions, Signs and Symptoms 70618
      Pathologic Processes 34780
        Shock 656
          Systemic Inflammatory Response Syndrome 637
            Sepsis 626
              Fungemia + 12
              Neonatal Sepsis 4
              Parasitemia + 234
              Viremia + 3
              bacterial sepsis + 212
              toxic shock syndrome 62
paths to the root