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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Borrelia Infections
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Accession:DOID:9004477 term browser browse the term
Definition:Infections with bacteria of the genus BORRELIA.
Synonyms:exact_synonym: Borrelia Infection
 primary_id: MESH:D001899
 xref: EFO:1000842


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Lyme disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 ISO protein:increased expression:synovial fluid RGD PMID:23371320 RGD:7488895 NCBI chr15:129,172,743...129,176,069 JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 severity ISO RGD PMID:12847259 RGD:7257681 NCBI chr15:120,219,657...120,230,203 JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:21387014 RGD:5508754 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO mRNA:increased expression:skin RGD PMID:19461880 RGD:6483813 NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418 		JBrowse link
Lyme Neuroborreliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 chemokine (C-C motif) ligand 2 ISO protein:increased expression:serum (human) RGD PMID:16358960 RGD:11528571 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CD40 CD40 molecule ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,709 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:24239846 RGD:39939054 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G LOC110258578 interleukin-1 beta-like ISO RGD PMID:23134838 RGD:7193053
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15436
    disease by infectious agent 2133
      Bacterial Infections and Mycoses 1042
        bacterial infectious disease 792
          Gram-Negative Bacterial Infections 192
            Borrelia Infections 9
              Borrelia miyamotoi disease 0
              Lyme disease + 9
              relapsing fever + 0
paths to the root