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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Borrelia Infections
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Accession:DOID:9004477 term browser browse the term
Definition:Infections with bacteria of the genus BORRELIA.
Synonyms:exact_synonym: Borrelia Infection
 primary_id: MESH:D001899
 xref: EFO:1000842


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Lyme disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 ISO protein:increased expression:synovial fluid RGD PMID:23371320 RGD:7488895 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 severity IMP RGD PMID:12847259 RGD:7257681 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Mir146 microRNA 146 exacerbates IMP RGD PMID:24967703 RGD:126925141 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IMP RGD PMID:21387014 RGD:5508754 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Plaur plasminogen activator, urokinase receptor IMP
ISO		 mRNA:increased expression:skin RGD PMID:19461880 PMID:19461880 RGD:6483813, RGD:6483813 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
Lyme Neuroborreliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO protein:increased expression:serum (human) RGD PMID:16358960 RGD:11528571 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Cd40 CD40 antigen ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 treatment ISO RGD PMID:24239846 RGD:39939054 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:23134838 RGD:7193053 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16268
    disease by infectious agent 2241
      Bacterial Infections and Mycoses 1086
        bacterial infectious disease 832
          Gram-Negative Bacterial Infections 201
            Borrelia Infections 10
              Borrelia miyamotoi disease 0
              Lyme disease + 10
              relapsing fever + 0
paths to the root