RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Borrelia Infections
Accession: DOID:9004477
browse the term
Definition: Infections with bacteria of the genus BORRELIA.
Synonyms: exact_synonym: Borrelia Infection
primary_id: MESH:D001899
xref: EFO:1000842
G
CCL20
C-C motif chemokine ligand 20
IEP
protein:increased expression:synovial fluid
RGD
PMID:23371320
RGD:7488895
NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
G
CXCR2
C-X-C motif chemokine receptor 2
severity
ISO
RGD
PMID:12847259
RGD:7257681
NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
G
MIR146A
microRNA 146a
exacerbates
ISO
RGD
PMID:24967703
RGD:126925141
NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450
G
NOD2
nucleotide binding oligomerization domain containing 2
ISO
RGD
PMID:21387014
RGD:5508754
NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077
G
PLAUR
plasminogen activator, urokinase receptor
ISO IEP
mRNA:increased expression:skin
RGD
PMID:19461880 PMID:19461880
RGD:6483813 , RGD:6483813
NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547
G
CCL2
C-C motif chemokine ligand 2
IEP
protein:increased expression:serum (human)
RGD
PMID:16358960
RGD:11528571
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
G
CD40
CD40 molecule
IEP
protein:increased expression:cerebrospinal fluid (human)
RGD
PMID:16463218
RGD:11352252
NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
G
CD40LG
CD40 ligand
IEP
protein:increased expression:cerebrospinal fluid (human)
RGD
PMID:16463218
RGD:11352252
NCBI chr X:136,648,158...136,660,390
Ensembl chr X:136,648,158...136,660,390
G
CXCL8
C-X-C motif chemokine ligand 8
treatment
IEP
RGD
PMID:24239846
RGD:39939054
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
G
IL1B
interleukin 1 beta
ISO
RGD
PMID:23134838
RGD:7193053
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all