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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Borrelia Infections
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Accession:DOID:9004477 term browser browse the term
Definition:Infections with bacteria of the genus BORRELIA.
Synonyms:exact_synonym: Borrelia Infection
 primary_id: MESH:D001899
 xref: EFO:1000842


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Lyme disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 ISO protein:increased expression:synovial fluid RGD PMID:23371320 RGD:7488895 NCBI chr25:40,506,385...40,509,903
Ensembl chr25:40,506,753...40,509,709 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 severity ISO RGD PMID:12847259 RGD:7257681 NCBI chr37:24,831,351...24,846,387
Ensembl chr37:24,843,171...24,844,247 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:21387014 RGD:5508754 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO mRNA:increased expression:skin RGD PMID:19461880 RGD:6483813 NCBI chr 1:111,476,804...111,490,876
Ensembl chr 1:111,476,893...111,490,880 		JBrowse link
Lyme Neuroborreliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 C-C motif chemokine ligand 2 ISO protein:increased expression:serum (human) RGD PMID:16358960 RGD:11528571 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CD40 CD40 molecule ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301 		JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:24239846 RGD:39939054 NCBI chr13:62,435,035...62,438,354
Ensembl chr13:62,434,422...62,438,354 		JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:23134838 RGD:7193053 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15757
    disease by infectious agent 2168
      Bacterial Infections and Mycoses 1053
        bacterial infectious disease 798
          Gram-Negative Bacterial Infections 188
            Borrelia Infections 9
              Borrelia miyamotoi disease 0
              Lyme disease + 9
              relapsing fever + 0
paths to the root