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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Borrelia Infections
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Accession:DOID:9004477 term browser browse the term
Definition:Infections with bacteria of the genus BORRELIA.
Synonyms:exact_synonym: Borrelia Infection
 primary_id: MESH:D001899
 xref: EFO:1000842


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Lyme disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 ISO protein:increased expression:synovial fluid RGD PMID:23371320 RGD:7488895 NCBI chr 9:91,837,139...91,839,736 JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 severity ISO RGD PMID:12847259 RGD:7257681 NCBI chr 9:75,729,493...75,735,868 JBrowse link
G Mir146a microRNA 146a exacerbates ISO RGD PMID:24967703 RGD:126925141 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO RGD PMID:21387014 RGD:5508754 NCBI chr19:34,555,832...34,596,281 JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO mRNA:increased expression:skin RGD PMID:19461880 PMID:19461880 RGD:6483813, RGD:6483813 NCBI chr 1:89,181,363...89,196,308 JBrowse link
Lyme Neuroborreliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO protein:increased expression:serum (human) RGD PMID:16358960 RGD:11528571 NCBI chr10:67,503,077...67,504,875 JBrowse link
G Cd40 CD40 molecule ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr 3:174,209,113...174,224,592 JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr  X:140,164,341...140,176,057 JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:23134838 RGD:7193053 NCBI chr 3:137,030,200...137,036,581 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19139
    disease by infectious agent 2254
      Bacterial Infections and Mycoses 1118
        bacterial infectious disease 824
          Gram-Negative Bacterial Infections 200
            Borrelia Infections 9
              Borrelia miyamotoi disease 0
              Lyme disease + 9
              relapsing fever + 0
paths to the root