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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Experimental Leukemia
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Accession:DOID:9004441 term browser browse the term
Definition:Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
Synonyms:exact_synonym: Animal Leukemia Model;   Animal Leukemia Models;   Experimental Leukemias
 primary_id: MESH:D007942
 alt_id: RDO:0004956



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Experimental Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene treatment ISO RGD PMID:20890046 RGD:11038805 NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:44,489,410...44,571,176
JBrowse link
G Cbx7 chromobox 7 ISO RGD PMID:25434821 RGD:11352713 NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO RGD PMID:10090949 RGD:11251764 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 treatment ISO RGD PMID:22781593 RGD:11352669 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Il1a interleukin 1 alpha treatment ISO RGD PMID:2117483 RGD:11051972 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Lat2 linker for activation of T cells family, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32587277 NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288
JBrowse link
G Nras NRAS proto-oncogene, GTPase induced IAGP DNA:transversion mutation, loss of heterozygosity:cds: RGD PMID:9142215 RGD:11535063 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32417439 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Runx1 RUNX family transcription factor 1 treatment ISO RGD PMID:19236814 RGD:11251683 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19145
    disease of cellular proliferation 7895
      Experimental Neoplasms 644
        Experimental Leukemia 9
          Avian Leukosis 0
          Leukemia L1210 0
          Leukemia L5178 0
          Leukemia P388 0
Path 2
Term Annotations click to browse term
  disease 19145
    disease of anatomical entity 18457
      Hemic and Lymphatic Diseases 4334
        hematopoietic system disease 3842
          Hematologic Neoplasms 1088
            hematologic cancer 1088
              leukemia 660
                Experimental Leukemia 9
                  Avian Leukosis 0
                  Leukemia L1210 0
                  Leukemia L5178 0
                  Leukemia P388 0
paths to the root