RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Experimental Leukemia
Accession: DOID:9004441
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Definition: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
Synonyms: exact_synonym: Animal Leukemia Model; Animal Leukemia Models; Experimental Leukemias
primary_id: MESH:D007942
alt_id: RDO:0004956
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Cbl
Cbl proto-oncogene
treatment
ISO
RGD
PMID:20890046
RGD:11038805
NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:44,489,410...44,571,176
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Cbx7
chromobox 7
ISO
RGD
PMID:25434821
RGD:11352713
NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:111,460,656...111,477,973
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
RGD
PMID:10090949
RGD:11251764
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
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Fgfr1
Fibroblast growth factor receptor 1
treatment
ISO
RGD
PMID:22781593
RGD:11352669
NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
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Il1a
interleukin 1 alpha
treatment
ISO
RGD
PMID:2117483
RGD:11051972
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Lat2
linker for activation of T cells family, member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32587277
NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288
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Nras
NRAS proto-oncogene, GTPase
induced
IAGP
DNA:transversion mutation, loss of heterozygosity:cds:
RGD
PMID:9142215
RGD:11535063
NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
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Ptpn11
protein tyrosine phosphatase, non-receptor type 11
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32417439
NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
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Runx1
RUNX family transcription factor 1
treatment
ISO
RGD
PMID:19236814
RGD:11251683
NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
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