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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Transplant Rejection
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Accession:DOID:9004283 term browser browse the term
Definition:A process in which a transplant recipient's immune system attacks the transplanted organ or tissue. The rejection can be hyperacute (occurring within a few minutes), acute (occurring within days to months), or chronic (occurring over many years).

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Transplant Rejection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B treatment ISO human construct in rat model RGD PMID:27732750 RGD:329322881 NCBI chrNW_004624731:2,557,993...2,600,250
Ensembl chrNW_004624731:2,566,063...2,600,035 		JBrowse link
G Apoa1 apolipoprotein A1 ISO protein:decreased expression:plasma RGD PMID:21730889 RGD:7241209 NCBI chrNW_004624784:12,249,283...12,251,215
Ensembl chrNW_004624784:12,249,283...12,251,136 		JBrowse link
G Arrb1 arrestin beta 1 ISO mRNA:decreased expression:blood, leukocyte RGD PMID:21193245 RGD:13506894 NCBI chrNW_004624817:1,750,448...1,828,399
Ensembl chrNW_004624817:1,750,156...1,823,309 		JBrowse link
G Arrb2 arrestin beta 2 ISO mRNA, protein:decreased expression:blood, leukocyte, monocyte RGD PMID:21193245 RGD:13506894 NCBI chrNW_004624786:8,568,102...8,576,445
Ensembl chrNW_004624786:8,568,198...8,577,914 		JBrowse link
G Bad BCL2 associated agonist of cell death treatment ISO RGD PMID:31828147 RGD:35316072 NCBI chrNW_004624767:22,025,721...22,037,283
Ensembl chrNW_004624767:22,026,133...22,037,277 		JBrowse link
G Bag6 BAG cochaperone 6 susceptibility ISO DNA:haplotype: :rs10484558(human) RGD PMID:25111513 RGD:14390152 NCBI chrNW_004624754:24,559,483...24,571,073
Ensembl chrNW_004624754:24,559,801...24,571,073 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:31828147 RGD:35316072 NCBI chrNW_004624832:5,050,222...5,068,565
Ensembl chrNW_004624832:5,050,222...5,055,506 		JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:31828147 RGD:35316072 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344 		JBrowse link
G Cd274 CD274 molecule ISO RGD PMID:14662900 RGD:8657367 NCBI chrNW_004624736:9,991,851...10,017,047
Ensembl chrNW_004624736:9,996,156...10,013,814 		JBrowse link
G Cd4 CD4 molecule treatment ISO RGD PMID:1704648 PMID:11081762 RGD:10058956 RGD:10058974 NCBI chrNW_004624860:3,470,886...3,492,247
Ensembl chrNW_004624860:3,470,631...3,492,846 		JBrowse link
G Cd40 CD40 molecule disease_progression
treatment 		ISO associated with Diabetes Mellitus, Experimental RGD PMID:14698004 PMID:15221125 PMID:21472009 RGD:7248441 RGD:7248755 RGD:8547788 NCBI chrNW_004624790:8,475,640...8,485,927
Ensembl chrNW_004624790:8,476,158...8,485,856 		JBrowse link
G Cd40lg CD40 ligand treatment ISO associated with Diabetes Mellitus
protein:increased expression:blood, T cell 		RGD PMID:10949194 PMID:15016184 PMID:15808676 PMID:22948742 RGD:7248420 RGD:7248598 RGD:7248719 RGD:8547783 NCBI chrNW_004624808:10,472,028...10,484,407
Ensembl chrNW_004624808:10,472,572...10,484,338 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO RGD PMID:25121092 RGD:151347544 NCBI chrNW_004624894:2,324,480...2,357,389
Ensembl chrNW_004624894:2,324,501...2,357,723 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO RGD PMID:25121092 RGD:151347544 NCBI chrNW_004624894:2,305,815...2,322,264
Ensembl chrNW_004624894:2,305,820...2,322,505 		JBrowse link
G Col1a2 collagen type I alpha 2 chain ISO mRNA:increased expression:kidney RGD PMID:20150539 RGD:7248773 NCBI chrNW_004624813:1,174,071...1,209,929
Ensembl chrNW_004624813:1,174,224...1,209,616 		JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO mRNA:increased expression:kidney RGD PMID:20150539 RGD:7248773 NCBI chrNW_004624899:1,192,078...1,230,528
Ensembl chrNW_004624899:1,192,360...1,230,404 		JBrowse link
G Csf1 colony stimulating factor 1 ISO mRNA:increased expression:kidney RGD PMID:11981428 PMID:19196448 RGD:7257570 RGD:7257590 NCBI chrNW_004624772:5,663,374...5,705,965
Ensembl chrNW_004624772:5,663,070...5,707,753 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:24056626 RGD:151665812 NCBI chrNW_004624774:9,363,156...9,391,939
Ensembl chrNW_004624774:9,363,908...9,391,986 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:18589159 RGD:11039422 NCBI chrNW_004624795:3,162,999...3,167,248
Ensembl chrNW_004624795:3,163,009...3,166,594 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 susceptibility ISO DNA:SNP: :rs231775, korean(human)
DNA:SNP: :rs733618, chinese(human) 		RGD PMID:12096784 PMID:14551031 PMID:18074399 PMID:20940051 PMID:22418270 RGD:7204515 RGD:7204516 RGD:7204518 RGD:7204671 RGD:7204678 NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 severity ISO RGD PMID:28245475 RGD:27095950 NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 ISO DNA:SNP:promoter:g.-2668G>A (rs2671222) (human) RGD PMID:21452410 RGD:7257676 NCBI chrNW_004624823:6,857,649...6,861,219
Ensembl chrNW_004624823:6,859,356...6,860,426 		JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) treatment ISO RGD PMID:8443191 RGD:11040447 NCBI chrNW_004624746:14,254,811...14,268,034
Ensembl chrNW_004624746:14,254,193...14,268,034 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:10401760 RGD:7244165 NCBI chrNW_004624764:6,222,301...6,318,423
Ensembl chrNW_004624764:6,221,867...6,318,477 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:10656876 RGD:9685445 NCBI chrNW_004624737:7,011,792...7,193,903
Ensembl chrNW_004624737:7,084,818...7,191,918 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 treatment ISO RGD PMID:31828147 RGD:35316072 NCBI chrNW_004624849:1,521,996...1,625,878
Ensembl chrNW_004624849:1,525,235...1,625,893 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit treatment ISO RGD PMID:27784285 RGD:126781722 NCBI chrNW_004624800:6,781,848...6,874,221
Ensembl chrNW_004624800:6,802,901...6,874,196 		JBrowse link
G Faslg Fas ligand ISO mRNA, protein:increased expression:liver RGD PMID:10357921 RGD:14700698 NCBI chrNW_004624771:9,031,978...9,038,760
Ensembl chrNW_004624771:9,032,016...9,038,825 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa treatment ISO RGD PMID:10762218 RGD:9588604 NCBI chrNW_004624826:23,930...34,735 JBrowse link
G Foxp3 forkhead box P3 treatment ISO mRNA:increased expression:liver RGD PMID:17414718 PMID:21199671 PMID:28457422 RGD:38456005 RGD:38549577 RGD:38599144 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration ISO RGD PMID:22819311 RGD:9685732 NCBI chrNW_004624913:273,126...276,353
Ensembl chrNW_004624913:273,705...275,693 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 treatment ISO RGD PMID:28596681 RGD:13504864 NCBI chrNW_004624746:27,557,994...27,586,257
Ensembl chrNW_004624746:27,558,005...27,586,257 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:23435265 RGD:7244382 NCBI chrNW_004624733:32,284,793...32,310,980 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 ISO mRNA,protein:increased expression:lung:
mRNA:increased expression:Leukocytes, Mononuclear: 		RGD PMID:22172823 PMID:24508263 RGD:7245954 RGD:9686116 NCBI chrNW_004624733:32,521,318...32,527,499 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:23953577 RGD:12910541 NCBI chrNW_004624889:2,736,727...2,746,333 JBrowse link
G Ifng interferon gamma ISO RGD PMID:22564629 RGD:7364833 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO mRNA:increased expression:kidney RGD PMID:19249479 PMID:20500684 RGD:4892204 RGD:7495769 NCBI chrNW_004624780:922,524...978,687
Ensembl chrNW_004624780:923,744...970,519 		JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:17275523 PMID:22564629 PMID:23870834 RGD:11049523 RGD:7364833 RGD:7364994 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732 		JBrowse link
G Il13 interleukin 13 treatment ISO mRNA:increased expression:liver RGD PMID:17331844 PMID:17532783 PMID:17902182 RGD:10402939 RGD:8549629 RGD:8549647 NCBI chrNW_004624733:39,427,189...39,430,019
Ensembl chrNW_004624733:39,428,095...39,429,843 		JBrowse link
G Il15 interleukin 15 ISO mRNA:increased expression:liver RGD PMID:17532783 RGD:10402939 NCBI chrNW_004624853:1,059,625...1,144,799
Ensembl chrNW_004624853:1,128,519...1,144,941 		JBrowse link
G Il17a interleukin 17A treatment ISO protein:increased expression:liver, serum (rat) RGD PMID:20651239 PMID:21043049 PMID:23429965 RGD:4781440 RGD:9068426 RGD:9068938 NCBI chrNW_004624855:3,911,349...3,914,214
Ensembl chrNW_004624855:3,911,349...3,913,136 		JBrowse link
G Il18 interleukin 18 ISO RGD PMID:21962809 RGD:8655943 NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687 		JBrowse link
G Il18bp interleukin 18 binding protein ISO RGD PMID:21962809 RGD:8655943 NCBI chrNW_004624817:4,963,586...4,967,122
Ensembl chrNW_004624817:4,964,403...4,965,944 		JBrowse link
G Il1b interleukin 1 beta severity ISO DNA:snp:intron:g.3962C>T (human) RGD PMID:8094579 PMID:22663993 RGD:7175098 RGD:7401188 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO cornea transplant; human protein in a mouse model RGD PMID:9175817 RGD:8549799 NCBI chrNW_004624749:13,210,365...13,224,471
Ensembl chrNW_004624749:13,210,476...13,225,890 		JBrowse link
G Il2 interleukin 2 treatment ISO RGD PMID:3291556 PMID:18089405 PMID:22564629 RGD:10047078 RGD:7364833 RGD:8662936 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453 		JBrowse link
G Il21 interleukin 21 ISO associated with hepatitis B;DNA:SNPs, haplotype:intron, CDS:1472G>T, 5250C>T (rs2055979, rs4833837) (human) RGD PMID:23656167 RGD:127285550 NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta ameliorates ISO RGD PMID:9293878 RGD:42733040 NCBI chrNW_004624752:10,662,053...10,682,891
Ensembl chrNW_004624752:10,672,432...10,683,045 		JBrowse link
G Il5 interleukin 5 treatment ISO RGD PMID:11267027 RGD:11354977 NCBI chrNW_004624733:39,544,487...39,558,943
Ensembl chrNW_004624733:39,556,797...39,559,119 		JBrowse link
G Il7 interleukin 7 ISO mRNA:increased expression:liver RGD PMID:17532783 RGD:10402939 NCBI chrNW_004624744:12,562,536...12,604,037
Ensembl chrNW_004624744:12,567,661...12,604,074 		JBrowse link
G Itga4 integrin subunit alpha 4 treatment ISO RGD PMID:9721793 RGD:9698437 NCBI chrNW_004624844:3,264,794...3,353,355
Ensembl chrNW_004624844:3,265,110...3,354,087 		JBrowse link
G Kdr kinase insert domain receptor ISO RGD PMID:22997228 RGD:8549738 NCBI chrNW_004624761:14,330,224...14,380,680
Ensembl chrNW_004624761:14,330,489...14,379,051 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO mRNA:increased expression:liver: RGD PMID:9862859 RGD:12910749 NCBI chrNW_004624761:14,733,912...14,831,428 JBrowse link
G LOC101703821 HLA class II histocompatibility antigen, DQ beta 1 chain ISO RGD PMID:1547813 RGD:7421554 NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713 		JBrowse link
G Lta lymphotoxin alpha treatment ISO RGD PMID:2338821 PMID:8356596 RGD:8548835 RGD:8548836 NCBI chrNW_004624754:24,626,930...24,628,412
Ensembl chrNW_004624754:24,627,318...24,628,182 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:22845765 RGD:7241226 NCBI chrNW_004624878:39,282...47,386
Ensembl chrNW_004624878:39,358...47,075 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO RGD PMID:12717211 RGD:7349372 NCBI chrNW_004624766:21,493,125...21,522,535 JBrowse link
G Muc4 mucin 4, cell surface associated ISO RGD PMID:12717211 RGD:7349372 NCBI chrNW_004624730:61,153,753...61,176,859 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO cornea RGD PMID:22149555 RGD:7240566 NCBI chrNW_004624735:27,780,338...27,784,714
Ensembl chrNW_004624735:27,780,037...27,784,806 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment ISO RGD PMID:19399405 PMID:31828147 RGD:10413870 RGD:35316072 NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO RGD PMID:29218089 RGD:13504718 NCBI chrNW_004624800:5,600,215...5,619,020
Ensembl chrNW_004624800:5,600,212...5,619,004 		JBrowse link
G Nppa natriuretic peptide A treatment ISO RGD PMID:23826817 RGD:7297054 NCBI chrNW_004624818:1,147,654...1,149,722
Ensembl chrNW_004624818:1,147,974...1,148,927 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO protein:decreased activity:blood, mononuclear cell RGD PMID:10959477 RGD:7174721 NCBI chrNW_004624774:2,496,276...2,603,894
Ensembl chrNW_004624774:2,495,304...2,602,632 		JBrowse link
G Pdcd1 programmed cell death 1 severity ISO mRNA:increased expression:leukocytes, Mononuclear: RGD PMID:17198268 PMID:17489865 PMID:21518556 RGD:7248673 RGD:9589060 RGD:9589063 NCBI chrNW_004624847:5,732,922...5,741,908
Ensembl chrNW_004624847:5,732,767...5,742,269 		JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chrNW_004624918:1,052,640...1,293,138
Ensembl chrNW_004624918:1,052,567...1,293,192 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO RGD PMID:10458478 RGD:1625382 NCBI chrNW_004624774:9,432,765...9,469,690
Ensembl chrNW_004624774:9,432,541...9,469,881 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:17311089 RGD:8693431 NCBI chrNW_004624828:2,121,262...2,131,645
Ensembl chrNW_004624828:2,121,329...2,131,645 		JBrowse link
G Plat plasminogen activator, tissue type susceptibility ISO protein:increased expression:plasma (human) RGD PMID:11423054 RGD:11541079 NCBI chrNW_004624780:1,014,429...1,063,636
Ensembl chrNW_004624780:1,028,085...1,063,649 		JBrowse link
G Plau plasminogen activator, urokinase ISO mRNA, protein:increased expression:kidney (human) RGD PMID:14531820 RGD:7241140 NCBI chrNW_004624754:7,405,637...7,415,870
Ensembl chrNW_004624754:7,408,983...7,416,559 		JBrowse link
G Prrc2a proline rich coiled-coil 2A susceptibility ISO DNA:haplotype: :rs11538264(human) RGD PMID:25111513 RGD:14390152 NCBI chrNW_004624754:24,572,178...24,586,696
Ensembl chrNW_004624754:24,572,546...24,584,643 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 severity ISO protein:increased expression:liver, kidney (rat) RGD PMID:22834313 RGD:9854627 NCBI chrNW_004624754:23,811,008...23,815,432
Ensembl chrNW_004624754:23,807,272...23,815,417 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 treatment ISO RGD PMID:18178058 RGD:9835362 NCBI chrNW_004624816:4,496,848...4,519,782
Ensembl chrNW_004624816:4,496,856...4,519,911 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit treatment ISO RGD PMID:31828147 RGD:35316072 NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit treatment ISO RGD PMID:23196258 RGD:7777161 NCBI chrNW_004624907:1,806,784...1,829,686
Ensembl chrNW_004624907:1,806,874...1,829,417 		JBrowse link
G Sell selectin L ISO RGD PMID:11095659 RGD:7175511 NCBI chrNW_004624826:7,590,576...7,612,370
Ensembl chrNW_004624826:7,587,970...7,610,163 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO protein:increased expression:kidney, mononuclear cell RGD PMID:19201987 RGD:9999387 NCBI chrNW_004624749:11,347,602...11,371,113
Ensembl chrNW_004624749:11,347,609...11,371,330 		JBrowse link
G Spi1 Spi-1 proto-oncogene treatment ISO RGD PMID:24282365 RGD:9586451 NCBI chrNW_004624767:1,376,649...1,404,382
Ensembl chrNW_004624767:1,394,704...1,404,406 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 ISO DNA:SNP: :rs7574865 (human) RGD PMID:21237270 RGD:7207871 NCBI chrNW_004624854:4,975,724...5,056,940
Ensembl chrNW_004624854:4,976,507...5,057,391 		JBrowse link
G Tbxa2r thromboxane A2 receptor ISO RGD PMID:7964472 RGD:11059606 NCBI chrNW_004624828:6,291,010...6,312,438
Ensembl chrNW_004624828:6,291,167...6,309,482 		JBrowse link
G Tlr2 toll like receptor 2 ISO kidney
liver;DNA:SNP: :p.R753Q (human) 		RGD PMID:20038715 PMID:20090572 PMID:20628182 PMID:22042224 RGD:7207901 RGD:7240551 RGD:7240554 RGD:7240555 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833 		JBrowse link
G Tlr4 toll like receptor 4 ISO pancreatic islet RGD PMID:20038715 PMID:20642685 RGD:7240548 RGD:7240555 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
G Tnf tumor necrosis factor treatment ISO RGD PMID:2038191 PMID:2338821 PMID:8094579 RGD:7394793 RGD:7401188 RGD:8548836 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO RGD PMID:19298452 RGD:7245520 NCBI chrNW_004624818:894,470...922,806
Ensembl chrNW_004624818:896,150...922,710 		JBrowse link
G Tpmt thiopurine S-methyltransferase ISO RGD PMID:24121523 RGD:11038722 NCBI chrNW_004624756:8,511,275...8,532,100
Ensembl chrNW_004624756:8,511,315...8,531,745 		JBrowse link
G Tpo thyroid peroxidase ISO RGD PMID:19506389 RGD:7207487 NCBI chrNW_004624846:1,934,084...1,962,637
Ensembl chrNW_004624846:1,934,469...1,961,291 		JBrowse link
G Traf2 TNF receptor associated factor 2 treatment ISO RGD PMID:31828147 RGD:35316072 NCBI chrNW_004624760:952,574...973,511
Ensembl chrNW_004624760:952,574...965,661 		JBrowse link
G Xdh xanthine dehydrogenase treatment ISO RGD PMID:24768926 RGD:13209011 NCBI chrNW_004624738:13,116,317...13,180,935
Ensembl chrNW_004624738:13,115,982...13,181,352 		JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor ISO RGD PMID:9916935 RGD:11341701 NCBI chrNW_004624742:3,112,827...3,123,424
Ensembl chrNW_004624742:3,112,801...3,124,301 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:21489814 RGD:155260371 NCBI chrNW_004624809:7,538,568...7,548,272 JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chrNW_004624918:1,052,640...1,293,138
Ensembl chrNW_004624918:1,052,567...1,293,192 		JBrowse link
Chronic Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor treatment ISO RGD PMID:22217518 PMID:23769041 RGD:7245568 RGD:8695995 NCBI chrNW_004624754:24,138,086...24,140,900 JBrowse link
G C3 complement C3 treatment ISO RGD PMID:25122638 RGD:11040803 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946 		JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:22826618 RGD:11352297 NCBI chrNW_004624790:8,475,640...8,485,927
Ensembl chrNW_004624790:8,476,158...8,485,856 		JBrowse link
G Cd40lg CD40 ligand treatment ISO liver RGD PMID:22826618 RGD:11352297 NCBI chrNW_004624808:10,472,028...10,484,407
Ensembl chrNW_004624808:10,472,572...10,484,338 		JBrowse link
G F7 coagulation factor VII treatment ISO human protein in a rat model RGD PMID:12095034 RGD:11049508 NCBI chrNW_004624793:780,057...788,105
Ensembl chrNW_004624793:780,059...788,095 		JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO RGD PMID:22217518 RGD:7245568 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 ameliorates ISO RGD PMID:24312257 RGD:401700379 NCBI chrNW_004624907:1,266,348...1,279,258
Ensembl chrNW_004624907:1,266,348...1,278,699 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:23985719 RGD:10041002 NCBI chrNW_004624818:1,570,155...1,698,264
Ensembl chrNW_004624818:1,570,276...1,698,259 		JBrowse link
G Tnf tumor necrosis factor treatment ISO RGD PMID:24598936 RGD:10450586 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
Chronic Allograft Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 ISO RGD PMID:20176611 RGD:11541086 NCBI chrNW_004624736:37,063,540...37,127,772
Ensembl chrNW_004624736:37,063,246...37,126,702 		JBrowse link
G Alb albumin disease_progression ISO RGD PMID:24370342 RGD:11035281 NCBI chrNW_004624735:34,105,237...34,123,479
Ensembl chrNW_004624735:34,104,537...34,123,624 		JBrowse link
G Ccn2 cellular communication network factor 2 disease_progression ISO mRNA, protein:increased expression:kidney (rat) RGD PMID:19921985 RGD:150517553 NCBI chrNW_004624753:6,022,033...6,024,866
Ensembl chrNW_004624753:6,023,069...6,024,833 		JBrowse link
G Clu clusterin treatment ISO RGD PMID:22494435 RGD:9068431 NCBI chrNW_004624758:22,431,331...22,444,185
Ensembl chrNW_004624758:22,426,918...22,444,357 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:22845765 RGD:7241226 NCBI chrNW_004624878:39,282...47,386
Ensembl chrNW_004624878:39,358...47,075 		JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment ISO RGD PMID:18209025 RGD:9685339 NCBI chrNW_004624878:345,038...364,986
Ensembl chrNW_004624878:345,038...361,652 		JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO RGD PMID:11889420 RGD:11080974 NCBI chrNW_004624740:26,172,808...26,191,557
Ensembl chrNW_004624740:26,169,064...26,188,866 		JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO mRNA:increased expression:kidney: RGD PMID:11889420 PMID:15785371 RGD:10449491 RGD:11080974 NCBI chrNW_004624752:9,072,471...9,088,289
Ensembl chrNW_004624752:9,072,512...9,088,593 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO RGD PMID:11889420 RGD:11080974 NCBI chrNW_004624761:15,223,789...15,269,685
Ensembl chrNW_004624761:15,225,356...15,269,810 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO RGD PMID:11889420 RGD:11080974 NCBI chrNW_004624774:9,432,765...9,469,690
Ensembl chrNW_004624774:9,432,541...9,469,881 		JBrowse link
G Plau plasminogen activator, urokinase ISO protein:increased secretion:T lymphocyte (human) RGD PMID:16387096 RGD:7241259 NCBI chrNW_004624754:7,405,637...7,415,870
Ensembl chrNW_004624754:7,408,983...7,416,559 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO protein:increased expression:kidney: RGD PMID:16221712 RGD:13208600 NCBI chrNW_004624956:84,673...207,176
Ensembl chrNW_004624956:83,842...149,481 		JBrowse link
G Serpine1 serpin family E member 1 treatment ISO protein:increased expression:kidney: RGD PMID:16221712 PMID:18192922 RGD:13208600 RGD:13208601 NCBI chrNW_004624740:16,128,145...16,136,696
Ensembl chrNW_004624740:16,128,059...16,137,337 		JBrowse link
Chronic Lung Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 ISO mRNA:increased expression:lung RGD PMID:22305384 RGD:10395369 NCBI chrNW_004624738:27,747,770...27,831,213
Ensembl chrNW_004624738:27,747,696...27,834,054 		JBrowse link
Corneal Graft Rejection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule treatment ISO RGD PMID:22300371 RGD:41412184 NCBI chrNW_004624736:9,991,851...10,017,047
Ensembl chrNW_004624736:9,996,156...10,013,814 		JBrowse link
G Cd4 CD4 molecule treatment ISO RGD PMID:1358194 RGD:10059315 NCBI chrNW_004624860:3,470,886...3,492,247
Ensembl chrNW_004624860:3,470,631...3,492,846 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO human gene in a rat model RGD PMID:23723965 RGD:9684950 NCBI chrNW_004624749:13,210,365...13,224,471
Ensembl chrNW_004624749:13,210,476...13,225,890 		JBrowse link
G Tlr2 toll like receptor 2 treatment ISO RGD PMID:21918429 RGD:597538536 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833 		JBrowse link
heart transplant rejection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fto FTO alpha-ketoglutarate dependent dioxygenase ISO DNA:SNP: :rs17817449 (human) RGD PMID:30408245 RGD:329845888 NCBI chrNW_004624757:2,675,810...3,081,751
Ensembl chrNW_004624757:2,675,671...3,080,480 		JBrowse link
Primary Graft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 exacerbates ISO protein:increased expression:urine (rat) RGD PMID:19921985 RGD:150517553 NCBI chrNW_004624753:6,022,033...6,024,866
Ensembl chrNW_004624753:6,023,069...6,024,833 		JBrowse link
G Cd40lg CD40 ligand treatment ISO RGD PMID:12244161 RGD:7248713 NCBI chrNW_004624808:10,472,028...10,484,407
Ensembl chrNW_004624808:10,472,572...10,484,338 		JBrowse link
G Gata2 GATA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chrNW_004624961:147,685...155,614
Ensembl chrNW_004624961:143,358...154,003 		JBrowse link
G Gpx3 glutathione peroxidase 3 treatment ISO RGD PMID:29290803 RGD:401827126 NCBI chrNW_004624733:40,957,895...40,963,469
Ensembl chrNW_004624733:40,957,999...40,962,993 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:10666412 PMID:22617707 RGD:11520779 RGD:8547722 NCBI chrNW_004624828:2,432,584...2,451,997
Ensembl chrNW_004624828:2,432,550...2,453,071 		JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:21911153 RGD:11049478 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732 		JBrowse link
G Npy neuropeptide Y ISO mRNA, protein:decreased expression:blood, mononuclear cell RGD PMID:18981110 RGD:10448956 NCBI chrNW_004624739:6,277,704...6,285,454
Ensembl chrNW_004624739:6,277,612...6,285,397 		JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chrNW_004624826:7,510,039...7,544,332
Ensembl chrNW_004624826:7,511,646...7,537,924 		JBrowse link
G Senp1 SUMO specific peptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chrNW_004624816:4,173,321...4,231,711
Ensembl chrNW_004624816:4,179,890...4,232,312 		JBrowse link
G Tnf tumor necrosis factor treatment ISO liver RGD PMID:18972563 RGD:15023490 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chrNW_004624857:3,606,573...3,625,991
Ensembl chrNW_004624857:3,606,431...3,627,063 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14234
    disease of anatomical entity 13936
      immune system disease 4283
        Transplant Rejection 114
          Chronic Allograft Dysfunction + 26
          Corneal Graft Rejection 4
          Primary Graft Dysfunction 11
          heart transplant rejection 1
Path 2
Term Annotations click to browse term
  disease 14234
    disease of anatomical entity 13936
      Immune & Inflammatory Diseases 4782
        immune system disease 4283
          Transplant Rejection 114
            Chronic Allograft Dysfunction + 26
            Corneal Graft Rejection 4
            Primary Graft Dysfunction 11
            heart transplant rejection 1
paths to the root