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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Phyllodes Tumor
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Accession:DOID:9004240 term browser browse the term
Definition:A type of connective tissue neoplasm typically arising from intralobular stroma of the breast. It is characterized by the rapid enlargement of an asymmetric firm mobile mass. Histologically, its leaf-like stromal clefts are lined by EPITHELIAL CELLS. Rare phyllodes tumor of the prostate is also known.
Synonyms:exact_synonym: cystosarcoma phyllodes;   cystosarcoma phylloides;   phyllodes tumors
 primary_id: MESH:D003557
 alt_id: RDO:0004681
For additional species annotation, visit the Alliance of Genome Resources.

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Phyllodes Tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A severity ISO RGD PMID:17090194 RGD:2289654 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ctnnb1 catenin beta 1 ISO protein:increased expression:nucleus RGD PMID:12898599 RGD:2289832 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO protein:increased expression:tumor RGD PMID:11206334 RGD:2289951 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:11206334 RGD:2289951 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:11206334 RGD:2289951 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Flna filamin A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437033 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha severity ISO protein:increased expression:breast (human) RGD PMID:16168127 RGD:8694472 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase severity ISO RGD PMID:15044924 RGD:2292419 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Kmt2d lysine methyltransferase 2D ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437033 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
JBrowse link
G Med12 mediator complex subunit 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437033 NCBI chr  X:66,404,622...66,427,772
Ensembl chr  X:66,404,760...66,428,387
JBrowse link
G Nos3 nitric oxide synthase 3 ISO protein:increased expression:breast RGD PMID:15917410 RGD:2292077 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Pcna proliferating cell nuclear antigen disease_progression ISO RGD PMID:10374321 RGD:2315010 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Rara retinoic acid receptor, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437033 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rb1 RB transcriptional corepressor 1 severity ISO protein:increased expression:breast RGD PMID:15981808 RGD:2299889 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437033 NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489
JBrowse link
G Tfrc transferrin receptor ISO protein:increased expression:myoepithelial cell RGD PMID:2174150 RGD:2292026 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tp53 tumor protein p53 disease_progression ISO RGD PMID:16889904 RGD:2290545 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18032
    disease of cellular proliferation 7258
      cancer 5226
        cell type cancer 3547
          sarcoma 254
            Phyllodes Tumor 17
              benign breast phyllodes tumor 0
              benign prostate phyllodes tumor 0
              breast malignant phyllodes tumor 0
              prostate malignant phyllodes tumor 0
paths to the root