RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Protozoan Infections, Animal
Accession: DOID:9004157
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Definition: Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary.
Synonyms: exact_synonym: Animal Protozoan Infection
primary_id: MESH:D011529 ; RDO:0004961
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Ccl5
C-C motif chemokine ligand 5
ISO
mRNA, protein:increased expression:blood vessel endothelial cell
RGD
PMID:15710456
RGD:2307183
NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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Ccr2
C-C motif chemokine receptor 2
IMP
RGD
PMID:19741601
RGD:8661685
NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
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Cd209d
CD209d antigen
treatment
IMP
RGD
PMID:32391004
RGD:39939012
NCBI chr 8:3,921,824...3,928,548
Ensembl chr 8:3,921,824...3,928,555
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Foxp3
forkhead box P3
IEP
mRNA:decreased expression:placenta:
RGD
PMID:21923716
RGD:38501105
NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484
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Hspd1
heat shock protein 1 (chaperonin)
IEP
RGD
PMID:8881756
RGD:12910478
NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
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Ido1
indoleamine 2,3-dioxygenase 1
IMP
RGD
PMID:31231617
RGD:39939039
NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025
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Il17a
interleukin 17A
IEP
mRNA,protein:increased expression:placenta:
RGD
PMID:21923716
RGD:38501105
NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
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Il21
interleukin 21
IMP
RGD
PMID:23667536
RGD:127285360
NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785
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Il23a
interleukin 23, alpha subunit p19
IMP
RGD
PMID:15265921
RGD:39457943
NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
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Il2rb
interleukin 2 receptor, beta chain
ameliorates
IMP
RGD
PMID:11286020
RGD:42724468
NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471
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Il6
interleukin 6
IEP
mRNA:increased expression:placenta:
RGD
PMID:21923716
RGD:38501105
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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Ldlr
low density lipoprotein receptor
IMP
RGD
PMID:18316222
RGD:5490254
NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
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Mir146
microRNA 146
ameliorates
IMP
RGD
PMID:24582962
RGD:126925172
NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
IMP
RGD
PMID:25855987
RGD:11057198
NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
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Rorc
RAR-related orphan receptor gamma
IEP
mRNA:increased expression:placenta:
RGD
PMID:21923716
RGD:38501105
NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583
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Sting1
stimulator of interferon response cGAMP interactor 1
severity
IMP
RGD
PMID:31416833
RGD:39128220
NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607
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Pecam1
platelet/endothelial cell adhesion molecule 1
ISO
protein:decreased expression:serum (human)
RGD
PMID:25539588
RGD:11541121
NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454
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Mbl2
mannose-binding lectin (protein C) 2
susceptibility
ISO
DNA:polymorphisms, haplotype:promoter,exon:
RGD
PMID:19827946
RGD:12910843
NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
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Mir21a
microRNA 21a
IEP
RNA:increased expression:ileum
RGD
PMID:25838265
RGD:40925950
NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
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