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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Protozoan Infections, Animal
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Accession:DOID:9004157 term browser browse the term
Definition:Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary.
Synonyms:exact_synonym: Animal Protozoan Infection
 primary_id: MESH:D011529;   RDO:0004961


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Animal Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL5 C-C motif chemokine ligand 5 ISO mRNA, protein:increased expression:blood vessel endothelial cell RGD PMID:15710456 RGD:2307183 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:19741601 RGD:8661685 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G FOXP3 forkhead box P3 ISO mRNA:decreased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:8881756 RGD:12910478 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:31231617 RGD:39939039 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IL17A interleukin 17A ISO mRNA,protein:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL21 interleukin 21 ISO RGD PMID:23667536 RGD:127285360 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL23A interleukin 23 subunit alpha ISO RGD PMID:15265921 RGD:39457943 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta ameliorates ISO RGD PMID:11286020 RGD:42724468 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118 		JBrowse link
G IL6 interleukin 6 ISO mRNA:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G LDLR low density lipoprotein receptor ISO RGD PMID:18316222 RGD:5490254 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,462...11,133,820 		JBrowse link
G MIR146A microRNA 146a ameliorates ISO RGD PMID:24582962 RGD:126925172 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 ISO RGD PMID:25855987 RGD:11057198 NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348 		JBrowse link
G RORC RAR related orphan receptor C ISO mRNA:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr 1:151,806,071...151,831,802
Ensembl chr 1:151,806,071...151,831,845 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 severity ISO RGD PMID:31416833 RGD:39128220 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
babesiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PECAM1 platelet and endothelial cell adhesion molecule 1 IEP protein:decreased expression:serum (human) RGD PMID:25539588 RGD:11541121 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
cryptosporidiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MBL2 mannose binding lectin 2 susceptibility IAGP DNA:polymorphisms, haplotype:promoter,exon: RGD PMID:19827946 RGD:12910843 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MIR21 microRNA 21 ISO RNA:increased expression:ileum RGD PMID:25838265 RGD:40925950 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 29104
    Animal Diseases 1379
      Parasitic Diseases, Animal 22
        Protozoan Infections, Animal 18
          Animal Toxoplasmosis 15
          Bovine Trypanosomiasis 0
          Dourine 0
          babesiosis 1
          cryptosporidiosis 2
          parasitic Ichthyosporea infectious disease + 0
          theileriasis 0
Path 2
Term Annotations click to browse term
  disease 29104
    disease by infectious agent 2604
      parasitic infectious disease 331
        parasitic protozoa infectious disease 172
          Protozoan Infections, Animal 18
            Animal Toxoplasmosis 15
            Bovine Trypanosomiasis 0
            Dourine 0
            babesiosis 1
            cryptosporidiosis 2
            parasitic Ichthyosporea infectious disease + 0
            theileriasis 0
paths to the root