RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Protozoan Infections, Animal
Accession: DOID:9004157
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Definition: Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary.
Synonyms: exact_synonym: Animal Protozoan Infection
primary_id: MESH:D011529 ; RDO:0004961
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CCL5
C-C motif chemokine ligand 5
ISO
mRNA, protein:increased expression:blood vessel endothelial cell
RGD
PMID:15710456
RGD:2307183
NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
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CCR2
C-C motif chemokine receptor 2
ISO
RGD
PMID:19741601
RGD:8661685
NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698
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FOXP3
forkhead box P3
ISO
mRNA:decreased expression:placenta:
RGD
PMID:21923716
RGD:38501105
NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758
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HSPD1
heat shock protein family D (Hsp60) member 1
ISO
RGD
PMID:8881756
RGD:12910478
NCBI chr37:7,010,421...7,025,912
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IDO1
indoleamine 2,3-dioxygenase 1
ISO
RGD
PMID:31231617
RGD:39939039
NCBI chr16:25,391,759...25,407,161
Ensembl chr16:25,391,754...25,407,048
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IL17A
interleukin 17A
ISO
mRNA,protein:increased expression:placenta:
RGD
PMID:21923716
RGD:38501105
NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
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IL21
interleukin 21
ISO
RGD
PMID:23667536
RGD:127285360
NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266
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IL23A
interleukin 23 subunit alpha
ISO
RGD
PMID:15265921
RGD:39457943
NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359
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IL2RB
interleukin 2 receptor subunit beta
ameliorates
ISO
RGD
PMID:11286020
RGD:42724468
NCBI chr10:27,370,797...27,388,775
Ensembl chr10:27,370,797...27,388,775
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IL6
interleukin 6
ISO
mRNA:increased expression:placenta:
RGD
PMID:21923716
RGD:38501105
NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
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LDLR
low density lipoprotein receptor
ISO
RGD
PMID:18316222
RGD:5490254
NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355
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NR4A2
nuclear receptor subfamily 4 group A member 2
ISO
RGD
PMID:25855987
RGD:11057198
NCBI chr36:2,546,237...2,554,559
Ensembl chr36:2,547,421...2,552,780
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RORC
RAR related orphan receptor C
ISO
mRNA:increased expression:placenta:
RGD
PMID:21923716
RGD:38501105
NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453
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STING1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31416833
RGD:39128220
NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072
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PECAM1
platelet and endothelial cell adhesion molecule 1
ISO
protein:decreased expression:serum (human)
RGD
PMID:25539588
RGD:11541121
NCBI chr 9:12,166,124...12,219,553
Ensembl chr 9:12,166,775...12,219,778
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MBL1
mannose binding lectin 1
susceptibility
ISO
DNA:polymorphisms, haplotype:promoter,exon:
RGD
PMID:19827946
RGD:12910843
NCBI chr 4:29,419,886...29,424,377
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MIR21
microRNA mir-21
ISO
RNA:increased expression:ileum
RGD
PMID:25838265
RGD:40925950
NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624
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