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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Protozoan Infections, Animal
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Accession:DOID:9004157 term browser browse the term
Definition:Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary.
Synonyms:exact_synonym: Animal Protozoan Infection
 primary_id: MESH:D011529;   RDO:0004961



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Animal Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL5 C-C motif chemokine ligand 5 ISO mRNA, protein:increased expression:blood vessel endothelial cell RGD PMID:15710456 RGD:2307183 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:19741601 RGD:8661685 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698
JBrowse link
G FOXP3 forkhead box P3 ISO mRNA:decreased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:8881756 RGD:12910478 NCBI chr37:7,010,421...7,025,912 JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:31231617 RGD:39939039 NCBI chr16:25,391,759...25,407,161
Ensembl chr16:25,391,754...25,407,048
JBrowse link
G IL17A interleukin 17A ISO mRNA,protein:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IL21 interleukin 21 ISO RGD PMID:23667536 RGD:127285360 NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266
JBrowse link
G IL23A interleukin 23 subunit alpha ISO RGD PMID:15265921 RGD:39457943 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359
JBrowse link
G IL2RB interleukin 2 receptor subunit beta ameliorates ISO RGD PMID:11286020 RGD:42724468 NCBI chr10:27,370,797...27,388,775
Ensembl chr10:27,370,797...27,388,775
JBrowse link
G IL6 interleukin 6 ISO mRNA:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G LDLR low density lipoprotein receptor ISO RGD PMID:18316222 RGD:5490254 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355
JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 ISO RGD PMID:25855987 RGD:11057198 NCBI chr36:2,546,237...2,554,559
Ensembl chr36:2,547,421...2,552,780
JBrowse link
G RORC RAR related orphan receptor C ISO mRNA:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453
JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 severity ISO RGD PMID:31416833 RGD:39128220 NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072
JBrowse link
babesiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO protein:decreased expression:serum (human) RGD PMID:25539588 RGD:11541121 NCBI chr 9:12,166,124...12,219,553
Ensembl chr 9:12,166,775...12,219,778
JBrowse link
cryptosporidiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MBL1 mannose binding lectin 1 susceptibility ISO DNA:polymorphisms, haplotype:promoter,exon: RGD PMID:19827946 RGD:12910843 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G MIR21 microRNA mir-21 ISO RNA:increased expression:ileum RGD PMID:25838265 RGD:40925950 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15675
    Animal Diseases 1332
      Parasitic Diseases, Animal 20
        Protozoan Infections, Animal 17
          Animal Toxoplasmosis 14
          Bovine Trypanosomiasis 0
          Dourine 0
          babesiosis 1
          cryptosporidiosis 2
          parasitic Ichthyosporea infectious disease + 0
          theileriasis 0
Path 2
Term Annotations click to browse term
  disease 15675
    disease by infectious agent 2162
      parasitic infectious disease 305
        parasitic protozoa infectious disease 158
          Protozoan Infections, Animal 17
            Animal Toxoplasmosis 14
            Bovine Trypanosomiasis 0
            Dourine 0
            babesiosis 1
            cryptosporidiosis 2
            parasitic Ichthyosporea infectious disease + 0
            theileriasis 0
paths to the root