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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Protozoan Infections, Animal
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Accession:DOID:9004157 term browser browse the term
Definition:Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary.
Synonyms:exact_synonym: Animal Protozoan Infection
 primary_id: MESH:D011529;   RDO:0004961
For additional species annotation, visit the Alliance of Genome Resources.



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Animal Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 IEP mRNA, protein:increased expression:blood vessel endothelial cell RGD PMID:15710456 RGD:2307183 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:19741601 RGD:8661685 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd209d CD209d molecule treatment ISO RGD PMID:32391004 RGD:39939012 NCBI chr12:1,891,109...1,897,559
Ensembl chr12:1,891,113...1,901,171
JBrowse link
G Foxp3 forkhead box P3 ISO mRNA:decreased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:8881756 RGD:12910478 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:31231617 RGD:39939039 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Il17a interleukin 17A ISO mRNA,protein:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il21 interleukin 21 ISO RGD PMID:23667536 RGD:127285360 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il23a interleukin 23 subunit alpha ISO RGD PMID:15265921 RGD:39457943 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il2rb interleukin 2 receptor subunit beta ameliorates ISO RGD PMID:11286020 RGD:42724468 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
JBrowse link
G Il6 interleukin 6 ISO mRNA:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ldlr low density lipoprotein receptor ISO RGD PMID:18316222 RGD:5490254 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mir146a microRNA 146a ameliorates ISO RGD PMID:24582962 RGD:126925172 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 ISO RGD PMID:25855987 RGD:11057198 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Rorc RAR-related orphan receptor C ISO mRNA:increased expression:placenta: RGD PMID:21923716 RGD:38501105 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 severity ISO RGD PMID:31416833 RGD:39128220 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335
JBrowse link
babesiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO protein:decreased expression:serum (human) RGD PMID:25539588 RGD:11541121 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
cryptosporidiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbl2 mannose binding lectin 2 susceptibility ISO
ISS
DNA:polymorphisms, haplotype:promoter,exon: MouseDO
RGD
PMID:19827946 RGD:12910843 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mir21 microRNA 21 ISO RNA:increased expression:ileum RGD PMID:25838265 RGD:40925950 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18145
    Animal Diseases 1694
      Parasitic Diseases, Animal 23
        Protozoan Infections, Animal 19
          Animal Toxoplasmosis 16
          Bovine Trypanosomiasis 0
          Dourine 0
          babesiosis 1
          cryptosporidiosis 2
          parasitic Ichthyosporea infectious disease + 0
          theileriasis 0
Path 2
Term Annotations click to browse term
  disease 18145
    disease by infectious agent 2136
      parasitic infectious disease 321
        parasitic protozoa infectious disease 172
          Protozoan Infections, Animal 19
            Animal Toxoplasmosis 16
            Bovine Trypanosomiasis 0
            Dourine 0
            babesiosis 1
            cryptosporidiosis 2
            parasitic Ichthyosporea infectious disease + 0
            theileriasis 0
paths to the root