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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Bunyaviridae Infections
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Accession:DOID:9004137 term browser browse the term
Definition:Virus diseases caused by the BUNYAVIRIDAE.
Synonyms:exact_synonym: Bunyaviridae Infection;   Bunyavirus Infection;   Bunyavirus Infections
 primary_id: MESH:D002044;   RDO:0005081
For additional species annotation, visit the Alliance of Genome Resources.


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Bunyaviridae Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STAT2 signal transducer and activator of transcription 2 exacerbates ISO RGD PMID:30814285 RGD:41789623 NCBI chr 5:21,733,030...21,748,960
Ensembl chr 5:21,733,035...21,751,354
JBrowse link
Crimean-Congo hemorrhagic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNA1 interferon, alpha 1 susceptibility ISO DNA:SNP:promoter: -1823G>A (rs1332190)(human) RGD PMID:26694082 RGD:36174029 NCBI chr 1:201,515,835...201,516,477
Ensembl chr 1:201,736,694...201,750,298
JBrowse link
Hantavirus hemorrhagic fever with renal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin severity ISO RGD PMID:14555823 RGD:11035280 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,718,304
JBrowse link
G APOC3 apolipoprotein C3 disease_progression ISO RGD PMID:20797315 RGD:7207210 NCBI chr 9:44,211,171...44,213,538 JBrowse link
G CD163 CD163 molecule exacerbates ISO protein:increased expression:blood plasma (human)
protein:increased expression:CD14-positive, CD16-positive monocyte, blood plasma (human)
protein:increased expression:CD14-positive monocyte (human)
RGD PMID:25392926 PMID:25789628 PMID:29857122 RGD:127285679 RGD:127285683 RGD:127345131 NCBI chr 5:63,300,200...63,334,497
Ensembl chr 5:63,300,146...63,334,498
JBrowse link
G IFNG interferon gamma severity ISO protein:increased expression:serum RGD PMID:22613426 RGD:6893374 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 severity ISO RGD PMID:25658420 RGD:40400702 NCBI chr 3:51,868,549...51,902,454
Ensembl chr 3:51,803,165...51,951,383
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO protein:increased expression:T cell RGD PMID:21436245 RGD:5147436 NCBI chr10:64,948,149...65,001,320
Ensembl chr10:64,948,552...65,001,173
JBrowse link
G IL33 interleukin 33 severity ISO RGD PMID:25658420 RGD:40400702 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,435...215,941,840
JBrowse link
G ITGB3 integrin subunit beta 3 severity ISO protein:increased expression:platelet RGD PMID:18419255 RGD:6907404 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,505...16,752,292
JBrowse link
G SLA-DRB1 MHC class II histocompatibility antigen SLA-DRB1 susceptibility ISO DNA:polymorphism:cds:HLA-DRB5*0101-0201 (human) RGD PMID:25169964 RGD:40818303 NCBI chr 7:24,901,386...24,914,016
Ensembl chr 7:24,881,775...24,914,053
JBrowse link
Hantavirus Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB3 integrin subunit beta 3 ISO RGD PMID:15886525 RGD:6907410 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,505...16,752,292
JBrowse link
G MKI67 marker of proliferation Ki-67 ISO RGD PMID:21795350 RGD:6483519 NCBI chr14:137,266,622...137,296,312 JBrowse link
Korean hemorrhagic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 ISO mRNA:increased expression:lung RGD PMID:17878294 RGD:2325989 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,782...43,328,735
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha treatment ISO RGD PMID:17878294 RGD:2325989 NCBI chr10:64,948,149...65,001,320
Ensembl chr10:64,948,552...65,001,173
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13613
    disease by infectious agent 1783
      viral infectious disease 1490
        RNA Virus Infections 1298
          Bunyaviridae Infections 13
            Crimean-Congo hemorrhagic fever 1
            Hantavirus Infections + 11
            La Crosse encephalitis 0
            Nairobi Sheep Disease 0
            Phlebotomus fever 0
            Rift Valley fever 0
paths to the root