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Term:AIDS Dementia Complex
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Accession:DOID:9004086 term browser browse the term
Definition:A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Synonyms:exact_synonym: AIDS Encephalopathies;   AIDS Encephalopathy;   AIDS Related Dementia Complex;   Acquired-Immune Deficiency Syndrome Dementia Complex;   HAND;   HIV 1 Associated Cognitive Motor Complex;   HIV 1 Cognitive and Motor Complex;   HIV Associated Cognitive Motor Complex;   HIV Dementia;   HIV Dementias;   HIV Encephalopathies;   HIV Encephalopathy;   HIV-associated neurocognitive disorders
 primary_id: MESH:D015526;   RDO:0006901
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AIDS Dementia Complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link NW_004936504 5,985,407 5,987,453 RGD:9068941
G Epo erythropoietin JBrowse link NW_004936543 742,722 745,332 RGD:9068941
G Gc GC vitamin D binding protein JBrowse link NW_004936598 3,220,029 3,256,091 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004936783 1,251,678 1,256,807 RGD:9068941
G Insr insulin receptor JBrowse link NW_004936588 4,345,306 4,453,380 RGD:9068941
G Irs1 insulin receptor substrate 1 JBrowse link NW_004936525 9,064,442 9,125,972 RGD:9068941
G Npy neuropeptide Y JBrowse link NW_004936478 1,289,437 1,296,819 RGD:9068941
G Oprm1 opioid receptor mu 1 JBrowse link NW_004936489 6,506,207 6,567,136 RGD:9068941
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004936492 2,353,840 2,368,573 RGD:9068941

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Path 1
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  disease 11417
    syndrome 4542
      acquired immunodeficiency syndrome 35
        AIDS Dementia Complex 9
Path 2
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  disease 11417
    disease of anatomical entity 11086
      Urogenital Diseases 3381
        Female Urogenital Diseases and Pregnancy Complications 1632
          Female Urogenital Diseases 1372
            female reproductive system disease 1368
              Sexually Transmitted Diseases 162
                Viral Sexually Transmitted Diseases 158
                  human immunodeficiency virus infectious disease 153
                    acquired immunodeficiency syndrome 35
                      AIDS Dementia Complex 9
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