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Term:AIDS Dementia Complex
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Accession:DOID:9004086 term browser browse the term
Definition:A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Synonyms:exact_synonym: AIDS Encephalopathies;   AIDS Encephalopathy;   AIDS Related Dementia Complex;   Acquired-Immune Deficiency Syndrome Dementia Complex;   HAND;   HIV 1 Associated Cognitive Motor Complex;   HIV 1 Cognitive and Motor Complex;   HIV Associated Cognitive Motor Complex;   HIV Dementia;   HIV Dementias;   HIV Encephalopathies;   HIV Encephalopathy;   HIV-associated neurocognitive disorders
 primary_id: MESH:D015526;   RDO:0006901
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AIDS Dementia Complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRB2 adrenoceptor beta 2 JBrowse link 2 150,032,649 150,035,591 RGD:9068941
G EPO erythropoietin JBrowse link 3 8,620,508 8,622,936 RGD:9068941
G GC GC vitamin D binding protein JBrowse link 8 68,326,293 68,360,262 RGD:9068941
G INSR insulin receptor JBrowse link 2 71,797,209 71,939,923 RGD:9068941
G IRS1 insulin receptor substrate 1 JBrowse link 15 128,245,846 128,307,321 RGD:9068941
G LOC110258578 interleukin-1 beta-like RGD:9068941
G NPY neuropeptide Y JBrowse link 18 47,985,796 47,993,726 RGD:9068941
G OPRM1 opioid receptor mu 1 JBrowse link 1 12,634,125 12,702,295 RGD:9068941
G PDGFB platelet derived growth factor subunit B RGD:9068941

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  disease 12016
    syndrome 4729
      acquired immunodeficiency syndrome 39
        AIDS Dementia Complex 9
Path 2
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  disease 12016
    disease of anatomical entity 11623
      Urogenital Diseases 3525
        Female Urogenital Diseases and Pregnancy Complications 1694
          Female Urogenital Diseases 1416
            female reproductive system disease 1412
              Sexually Transmitted Diseases 170
                Viral Sexually Transmitted Diseases 166
                  human immunodeficiency virus infectious disease 162
                    acquired immunodeficiency syndrome 39
                      AIDS Dementia Complex 9
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