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Term:AIDS Dementia Complex
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Accession:DOID:9004086 term browser browse the term
Definition:A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Synonyms:exact_synonym: AIDS Encephalopathies;   AIDS Encephalopathy;   AIDS Related Dementia Complex;   Acquired-Immune Deficiency Syndrome Dementia Complex;   HAND;   HIV 1 Associated Cognitive Motor Complex;   HIV 1 Cognitive and Motor Complex;   HIV Associated Cognitive Motor Complex;   HIV Dementia;   HIV Dementias;   HIV Encephalopathies;   HIV Encephalopathy;   HIV-associated neurocognitive disorders
 primary_id: MESH:D015526;   RDO:0006901
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AIDS Dementia Complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenergic receptor, beta 2 JBrowse link 18 62,177,713 62,179,981 RGD:11554173
G Epo erythropoietin JBrowse link 5 137,483,020 137,485,816 RGD:10395393
G Gc vitamin D binding protein JBrowse link 5 89,417,511 89,457,898 RGD:5509882
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:1626641
G Insr insulin receptor JBrowse link 8 3,150,922 3,279,649 RGD:10403033
G Irs1 insulin receptor substrate 1 JBrowse link 1 82,233,105 82,291,439 RGD:10403033
G Npy neuropeptide Y JBrowse link 6 49,822,710 49,829,507 RGD:10431910
G Oprm1 opioid receptor, mu 1 JBrowse link 10 6,758,593 7,038,209 RGD:11554173
G Pdgfb platelet derived growth factor, B polypeptide JBrowse link 15 79,995,865 80,024,614 RGD:6482787

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  disease 12617
    syndrome 4912
      acquired immunodeficiency syndrome 39
        AIDS Dementia Complex 9
Path 2
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  disease 12617
    disease of anatomical entity 12180
      Urogenital Diseases 3650
        Female Urogenital Diseases and Pregnancy Complications 1738
          Female Urogenital Diseases 1450
            female reproductive system disease 1446
              Sexually Transmitted Diseases 177
                Viral Sexually Transmitted Diseases 172
                  human immunodeficiency virus infectious disease 167
                    acquired immunodeficiency syndrome 39
                      AIDS Dementia Complex 9
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