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ONTOLOGY REPORT - ANNOTATIONS


Term:AIDS Dementia Complex
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Accession:DOID:9004086 term browser browse the term
Definition:A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Synonyms:exact_synonym: AIDS Encephalopathies;   AIDS Encephalopathy;   AIDS Related Dementia Complex;   Acquired-Immune Deficiency Syndrome Dementia Complex;   HAND;   HIV 1 Associated Cognitive Motor Complex;   HIV 1 Cognitive and Motor Complex;   HIV Associated Cognitive Motor Complex;   HIV Dementia;   HIV Dementias;   HIV Encephalopathies;   HIV Encephalopathy;   HIV-associated neurocognitive disorders
 primary_id: MESH:D015526;   RDO:0006901
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AIDS Dementia Complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRB2 adrenoceptor beta 2 JBrowse link 5 148,826,593 148,828,634 RGD:11554173
G EPO erythropoietin JBrowse link 7 100,720,468 100,723,700 RGD:10395393
G GC GC vitamin D binding protein JBrowse link 4 71,741,693 71,805,520 RGD:5509882
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:1626641
G INSR insulin receptor JBrowse link 19 7,112,257 7,294,414 RGD:10403033
G IRS1 insulin receptor substrate 1 JBrowse link 2 226,731,317 226,798,790 RGD:10403033
G NPY neuropeptide Y JBrowse link 7 24,284,190 24,291,862 RGD:10431910
G OPRM1 opioid receptor mu 1 JBrowse link 6 154,010,496 154,246,867 RGD:11554173
G PDGFB platelet derived growth factor subunit B JBrowse link 22 39,223,359 39,244,982 RGD:6482787

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Path 1
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  disease 16489
    syndrome 5587
      acquired immunodeficiency syndrome 45
        AIDS Dementia Complex 9
Path 2
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  disease 16489
    disease of anatomical entity 15414
      Urogenital Diseases 4318
        Female Urogenital Diseases and Pregnancy Complications 1867
          Female Urogenital Diseases 1562
            female reproductive system disease 1558
              Sexually Transmitted Diseases 183
                Viral Sexually Transmitted Diseases 179
                  human immunodeficiency virus infectious disease 174
                    acquired immunodeficiency syndrome 45
                      AIDS Dementia Complex 9
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