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Term:AIDS Dementia Complex
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Accession:DOID:9004086 term browser browse the term
Definition:A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Synonyms:exact_synonym: AIDS Encephalopathies;   AIDS Encephalopathy;   AIDS Related Dementia Complex;   Acquired-Immune Deficiency Syndrome Dementia Complex;   HAND;   HIV 1 Associated Cognitive Motor Complex;   HIV 1 Cognitive and Motor Complex;   HIV Associated Cognitive Motor Complex;   HIV Dementia;   HIV Dementias;   HIV Encephalopathies;   HIV Encephalopathy;   HIV-associated neurocognitive disorders
 primary_id: MESH:D015526;   RDO:0006901
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AIDS Dementia Complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRB2 adrenoceptor beta 2 JBrowse link 4 60,048,502 60,050,447 RGD:9068941
G EPO erythropoietin JBrowse link 6 8,994,211 8,995,954 RGD:9068941
G GC GC vitamin D binding protein JBrowse link 13 60,795,305 60,828,038 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:9068941
G INSR insulin receptor JBrowse link 20 52,017,261 52,136,061 RGD:9068941
G IRS1 insulin receptor substrate 1 JBrowse link 25 39,624,554 39,687,991 RGD:9068941
G NPY neuropeptide Y JBrowse link 14 37,824,579 37,831,289 RGD:9068941
G OPRM1 opioid receptor mu 1 JBrowse link 1 43,972,915 44,037,477 RGD:9068941
G PDGFB platelet derived growth factor subunit B JBrowse link 10 25,798,877 25,819,422 RGD:9068941

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Path 1
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  disease 12065
    syndrome 4742
      acquired immunodeficiency syndrome 38
        AIDS Dementia Complex 9
Path 2
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  disease 12065
    disease of anatomical entity 11668
      Urogenital Diseases 3519
        Female Urogenital Diseases and Pregnancy Complications 1691
          Female Urogenital Diseases 1406
            female reproductive system disease 1402
              Sexually Transmitted Diseases 172
                Viral Sexually Transmitted Diseases 168
                  human immunodeficiency virus infectious disease 163
                    acquired immunodeficiency syndrome 38
                      AIDS Dementia Complex 9
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