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Term:AIDS Dementia Complex
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Accession:DOID:9004086 term browser browse the term
Definition:A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Synonyms:exact_synonym: AIDS Encephalopathies;   AIDS Encephalopathy;   AIDS Related Dementia Complex;   Acquired-Immune Deficiency Syndrome Dementia Complex;   HAND;   HIV 1 Associated Cognitive Motor Complex;   HIV 1 Cognitive and Motor Complex;   HIV Associated Cognitive Motor Complex;   HIV Dementia;   HIV Dementias;   HIV Encephalopathies;   HIV Encephalopathy;   HIV-associated neurocognitive disorders
 primary_id: MESH:D015526;   RDO:0006901
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AIDS Dementia Complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link NW_004955415 5,515,157 5,517,198 RGD:9068941
G Epo erythropoietin JBrowse link NW_004955573 203,875 206,078 RGD:9068941
G Gc GC vitamin D binding protein JBrowse link NW_004955447 1,361,698 1,400,633 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
G Insr insulin receptor JBrowse link NW_004955563 1,867,400 2,011,845 RGD:9068941
G Irs1 insulin receptor substrate 1 JBrowse link NW_004955453 7,685,715 7,742,262 RGD:9068941
G Npy neuropeptide Y JBrowse link NW_004955410 26,348,388 26,355,232 RGD:9068941
G Oprm1 opioid receptor mu 1 JBrowse link NW_004955439 7,870,563 7,923,817 RGD:9068941
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004955413 25,150,702 25,166,987 RGD:9068941

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Path 1
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  disease 11284
    syndrome 4513
      acquired immunodeficiency syndrome 32
        AIDS Dementia Complex 9
Path 2
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  disease 11284
    disease of anatomical entity 10903
      Urogenital Diseases 3342
        Female Urogenital Diseases and Pregnancy Complications 1630
          Female Urogenital Diseases 1366
            female reproductive system disease 1362
              Sexually Transmitted Diseases 159
                Viral Sexually Transmitted Diseases 155
                  human immunodeficiency virus infectious disease 151
                    acquired immunodeficiency syndrome 32
                      AIDS Dementia Complex 9
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