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Term:AIDS Dementia Complex
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Accession:DOID:9004086 term browser browse the term
Definition:A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Synonyms:exact_synonym: AIDS Encephalopathies;   AIDS Encephalopathy;   AIDS Related Dementia Complex;   Acquired-Immune Deficiency Syndrome Dementia Complex;   HAND;   HIV 1 Associated Cognitive Motor Complex;   HIV 1 Cognitive and Motor Complex;   HIV Associated Cognitive Motor Complex;   HIV Dementia;   HIV Dementias;   HIV Encephalopathies;   HIV Encephalopathy;   HIV-associated neurocognitive disorders
 primary_id: MESH:D015526;   RDO:0006901
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AIDS Dementia Complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRB2 adrenoceptor beta 2 JBrowse link 5 150,267,321 150,269,339 RGD:9068941
G EPO erythropoietin JBrowse link 7 106,148,062 106,150,974 RGD:9068941
G GC GC vitamin D binding protein JBrowse link 4 58,749,384 58,792,073 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 2A 113,846,299 113,853,424 RGD:9068941
G INSR insulin receptor JBrowse link 19 7,255,444 7,411,916 RGD:9068941
G IRS1 insulin receptor substrate 1 JBrowse link 2B 232,785,822 232,853,997 RGD:9068941
G NPY neuropeptide Y JBrowse link 7 24,566,963 24,574,657 RGD:9068941
G OPRM1 opioid receptor mu 1 JBrowse link 6 156,517,666 156,627,758 RGD:9068941
G PDGFB platelet derived growth factor subunit B JBrowse link 22 37,944,018 37,964,883 RGD:9068941

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Path 1
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  disease 11912
    syndrome 4700
      acquired immunodeficiency syndrome 36
        AIDS Dementia Complex 9
Path 2
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  disease 11912
    disease of anatomical entity 11517
      Urogenital Diseases 3480
        Female Urogenital Diseases and Pregnancy Complications 1678
          Female Urogenital Diseases 1400
            female reproductive system disease 1396
              Sexually Transmitted Diseases 165
                Viral Sexually Transmitted Diseases 161
                  human immunodeficiency virus infectious disease 156
                    acquired immunodeficiency syndrome 36
                      AIDS Dementia Complex 9
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