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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Fungal Keratitis
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Accession:DOID:9004055 term browser browse the term
Definition:Fungal infection of the cornea which can follow from an injury or from wearing contact lenses. It usually develops very quickly, and if left untreated, can cause blindness.
Synonyms:exact_synonym: fungal infection of cornea;   keratomycosis;   mycotic keratitis
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
Fungal Keratitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain family 7, member a treatment IMP
IEP		 mRNA:increased expression:cornea RGD PMID:26963514 PMID:26963514 RGD:11526921, RGD:11526921 NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742 		JBrowse link
G Tlr4 toll-like receptor 4 IMP associated with Aspergillosis RGD PMID:20617171 RGD:7794847 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment ISO
IEP
IDA		 mRNA:increased expression:cornea RGD PMID:26963514 PMID:26963514 PMID:26963514 RGD:11526921, RGD:11526921, RGD:11526921 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Tslp thymic stromal lymphopoietin disease_progression IMP RGD PMID:29550278 PMID:30853520 RGD:38549371, RGD:38549574 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18170
    sensory system disease 6945
      eye disease 3286
        corneal disease 216
          keratitis 66
            Fungal Keratitis 4
Path 2
Term Annotations click to browse term
  disease 18170
    disease of anatomical entity 15603
      nervous system disease 13545
        Neurologic Manifestations 9853
          sensory system disease 6945
            eye disease 3286
              Eye Infections 58
                Fungal Eye Infections 5
                  Fungal Keratitis 4
paths to the root