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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Fungal Keratitis
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Accession:DOID:9004055 term browser browse the term
Definition:Fungal infection of the cornea which can follow from an injury or from wearing contact lenses. It usually develops very quickly, and if left untreated, can cause blindness.
Synonyms:exact_synonym: fungal infection of cornea;   keratomycosis;   mycotic keratitis


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Fungal Keratitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A treatment ISO mRNA:increased expression:cornea RGD PMID:26963514 PMID:26963514 RGD:11526921, RGD:11526921 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G TLR4 toll like receptor 4 ISO associated with Aspergillosis RGD PMID:20617171 RGD:7794847 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 treatment IEP
ISO		 mRNA:increased expression:cornea RGD PMID:26963514 PMID:26963514 PMID:26963514 RGD:11526921, RGD:11526921, RGD:11526921 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682 		JBrowse link
G TSLP thymic stromal lymphopoietin disease_progression ISO RGD PMID:29550278 PMID:30853520 RGD:38549371, RGD:38549574 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 29219
    sensory system disease 8030
      eye disease 4140
        corneal disease 279
          keratitis 66
            Fungal Keratitis 4
Path 2
Term Annotations click to browse term
  disease 29219
    disease of anatomical entity 23394
      nervous system disease 18908
        Neurologic Manifestations 12214
          sensory system disease 8030
            eye disease 4140
              Eye Infections 58
                Fungal Eye Infections 5
                  Fungal Keratitis 4
paths to the root