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ONTOLOGY REPORT - ANNOTATIONS


Term:Herpes Simplex Encephalitis
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Accession:DOID:9003870 term browser browse the term
Definition:An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)
Synonyms:exact_synonym: ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, SUSCEPTIBILITY TO, 2;   HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2;   Herpes Simplex Encephalitides;   Herpes Simplex Meningoencephalitides;   Herpes Simplex Meningoencephalitis;   Herpetic Acute Necrotizing Encephalitis;   Herpetic Encephalitides;   Herpetic Encephalitis;   Herpetic Meningoencephalitides;   Herpetic Meningoencephalitis;   IIAE2;   herpes encephalitis;   meningoencephalitis, herpes simplex virus
 primary_id: MESH:D020803
 alt_id: OMIM:613002;   RDO:0007432
For additional species annotation, visit the Alliance of Genome Resources.


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Herpes Simplex Encephalitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:7771554
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:8698664
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:7240516
G Calcr calcitonin receptor JBrowse link 4 28,627,439 28,702,559 RGD:7240516
G Ccr2 C-C motif chemokine receptor 2 RGD:8661752
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:8551839
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:8661752
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:8657070
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:11554173
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:8548806
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:8547868
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:8547867
RGD:8547868
G Stat4 signal transducer and activator of transcription 4 JBrowse link 9 54,340,649 54,457,753 RGD:8661706
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:11554173
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:8553026
RGD:5130178
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:8554872
RGD:11554173
RGD:7240710
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:5130178
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:5130178
G Traf3 Tnf receptor-associated factor 3 JBrowse link 6 135,610,698 135,720,247 RGD:11554173
G Unc93b1 unc-93 homolog B1, TLR signaling regulator JBrowse link 1 219,172,987 219,183,941 RGD:11554173
Herpes Simplex Encephalitis 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:8554872
G Unc93b1 unc-93 homolog B1, TLR signaling regulator JBrowse link 1 219,172,987 219,183,941 RGD:8554872
RGD:7240710
Herpes Simplex Encephalitis 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amn amnion associated transmembrane protein JBrowse link 6 135,724,455 135,731,896 RGD:8554872
G Traf3 Tnf receptor-associated factor 3 JBrowse link 6 135,610,698 135,720,247 RGD:8554872
RGD:7240710
Herpes Simplex Encephalitis 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:8554872
RGD:7240710
Herpes Simplex Encephalitis 7 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:7240710
RGD:8554872

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Path 1
Term Annotations click to browse term
  disease 15553
    disease by infectious agent 827
      viral infectious disease 511
        Viral Skin Diseases 62
          herpes simplex 52
            Herpes Simplex Encephalitis 32
              Herpes Simplex Encephalitis 1 2
              Herpes Simplex Encephalitis 3 2
              Herpes Simplex Encephalitis 4 1
              Herpes Simplex Encephalitis 7 1
Path 2
Term Annotations click to browse term
  disease 15553
    disease of anatomical entity 14837
      nervous system disease 10167
        sensory system disease 4596
          skin disease 2462
            Infectious Skin Diseases 146
              Viral Skin Diseases 62
                herpes simplex 52
                  Herpes Simplex Encephalitis 32
                    Herpes Simplex Encephalitis 1 2
                    Herpes Simplex Encephalitis 3 2
                    Herpes Simplex Encephalitis 4 1
                    Herpes Simplex Encephalitis 7 1
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