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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Carcinoma, Lewis Lung
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Accession:DOID:9003690 term browser browse the term
Definition:A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
Synonyms:primary_id: MESH:D018827
 xref: EFO:1001770


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Carcinoma, Lewis Lung term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 treatment ISO RGD PMID:16947020 RGD:7401280 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G Coq7 coenzyme Q7, hydroxylase susceptibility ISO RGD PMID:23166727 RGD:10402105 NCBI chrNW_004936501:5,035,986...5,043,864
Ensembl chrNW_004936501:5,034,224...5,043,909
JBrowse link
G Csf1r colony stimulating factor 1 receptor ameliorates ISO mouse cell line in a mouse model RGD PMID:20008303 RGD:150524291 NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923
JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:16767432 RGD:8655941 NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189
JBrowse link
G Il2 interleukin 2 treatment ISO RGD PMID:9399664 RGD:8663451 NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625
JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:21278795 RGD:36049796 NCBI chrNW_004936545:4,233,353...4,284,324
Ensembl chrNW_004936545:4,233,358...4,282,806
JBrowse link
G Jam3 junctional adhesion molecule 3 ISO RGD PMID:15994945 RGD:7488936 NCBI chrNW_004936684:1,689,594...1,762,066
Ensembl chrNW_004936684:1,692,089...1,762,087
JBrowse link
G Lect2 leukocyte cell derived chemotaxin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:30453282 NCBI chrNW_004936597:3,051,143...3,057,383
Ensembl chrNW_004936597:3,051,143...3,057,383
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 ameliorates ISO mouse cell line in a mouse model RGD PMID:29907597 RGD:151665504 NCBI chrNW_004936476:23,237,762...23,310,211
Ensembl chrNW_004936476:23,237,277...23,310,232
JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor treatment ISO mouse cell line in a mouse model RGD PMID:26111447 RGD:150521531 NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372
JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16565519 NCBI chrNW_004936492:10,185,096...10,244,466
Ensembl chrNW_004936492:10,187,206...10,225,989
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16465
    disease of cellular proliferation 6817
      Experimental Neoplasms 422
        Carcinoma, Lewis Lung 11
Path 2
Term Annotations click to browse term
  disease 16465
    disease of cellular proliferation 6817
      cancer 4940
        cell type cancer 3391
          carcinoma 2863
            Carcinoma, Lewis Lung 11
paths to the root