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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Carcinoma, Lewis Lung
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Accession:DOID:9003690 term browser browse the term
Definition:A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
Synonyms:primary_id: MESH:D018827
 xref: EFO:1001770


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Carcinoma, Lewis Lung term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 treatment ISO RGD PMID:16947020 RGD:7401280 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Coq7 coenzyme Q7, hydroxylase susceptibility ISO RGD PMID:23166727 RGD:10402105 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ameliorates ISO mouse cell line in a mouse model RGD PMID:20008303 RGD:150524291 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:16767432 RGD:8655941 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il2 interleukin 2 treatment ISO RGD PMID:9399664 RGD:8663451 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO RGD PMID:21278795 RGD:36049796 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Jam3 junctional adhesion molecule 3 ISO RGD PMID:15994945 RGD:7488936 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355 		JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:30453282 NCBI chr17:8,044,759...8,050,983
Ensembl chr17:8,044,759...8,050,983 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 ameliorates ISO mouse cell line in a mouse model RGD PMID:29907597 RGD:151665504 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor treatment ISO mouse cell line in a mouse model RGD PMID:26111447 RGD:150521531 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16565519 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21108
    disease of cellular proliferation 7662
      Experimental Neoplasms 638
        Carcinoma, Lewis Lung 11
Path 2
Term Annotations click to browse term
  disease 21108
    disease of cellular proliferation 7662
      cancer 5483
        cell type cancer 3746
          carcinoma 3218
            Carcinoma, Lewis Lung 11
paths to the root