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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Carcinoma, Lewis Lung
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Accession:DOID:9003690 term browser browse the term
Definition:A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
Synonyms:primary_id: MESH:D018827;   RDO:0007236
For additional species annotation, visit the Alliance of Genome Resources.


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Carcinoma, Lewis Lung term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 treatment ISO RGD PMID:16947020 RGD:7401280 NCBI chr 9:2,087,437...2,114,366 JBrowse link
G Coq7 coenzyme Q7, hydroxylase susceptibility ISO RGD PMID:23166727 RGD:10402105 NCBI chr 1:172,836,359...172,851,173 JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:16767432 RGD:8655941 NCBI chr 8:50,904,630...50,932,887 JBrowse link
G Il2 interleukin 2 treatment ISO RGD PMID:9399664 RGD:8663451 NCBI chr 2:120,004,862...120,009,566 JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO RGD PMID:21278795 RGD:36049796 NCBI chr 7:55,653,949...55,714,371 JBrowse link
G Jam3 junctional adhesion molecule 3 ISO RGD PMID:15994945 RGD:7488936 NCBI chr 8:25,508,461...25,569,306 JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:30453282 NCBI chr17:8,044,759...8,050,983 JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16565519 NCBI chr 7:20,830,042...20,914,990 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17160
    disease of cellular proliferation 6949
      Experimental Neoplasms 608
        Carcinoma, Lewis Lung 8
Path 2
Term Annotations click to browse term
  disease 17160
    disease of cellular proliferation 6949
      cancer 4897
        cell type cancer 3396
          carcinoma 2914
            Carcinoma, Lewis Lung 8
paths to the root