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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Granuloma, Foreign-Body
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Accession:DOID:9003615 term browser browse the term
Definition:Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.
Synonyms:exact_synonym: Foreign-Body Granulomas
 primary_id: MESH:D015745;   RDO:0006915
For additional species annotation, visit the Alliance of Genome Resources.


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Granuloma, Foreign-Body term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr9 toll-like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19797157 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17150
    Pathological Conditions, Signs and Symptoms 10222
      Pathologic Processes 6694
        Granuloma 31
          Granuloma, Foreign-Body 1
Path 2
Term Annotations click to browse term
  disease 17150
    disease of anatomical entity 16494
      Immune & Inflammatory Diseases 3891
        immune system disease 3257
          lymphatic system disease 1210
            lymphoproliferative syndrome 777
              Granuloma 31
                Granuloma, Foreign-Body 1
paths to the root