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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:AIDS-Related Complex
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Accession:DOID:9003393 term browser browse the term
Definition:A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.
Synonyms:exact_synonym: ARC;   Lymphadenopathy Syndrome;   Lymphadenopathy Syndromes
 primary_id: MESH:D000386;   RDO:0004787
 xref: EFO:0007137


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AIDS-Related Complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KLRK1 killer cell lectin like receptor K1 treatment ISO RGD PMID:23018378 RGD:39018554 NCBI chr27:35,634,938...35,658,978
Ensembl chr27:35,639,280...35,658,882 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17774
    disease by infectious agent 2126
      viral infectious disease 1622
        Slow Virus Diseases 42
          acquired immunodeficiency syndrome 38
            AIDS-Related Complex 1
Path 2
Term Annotations click to browse term
  disease 17774
    disease of anatomical entity 15146
      Urogenital Diseases 4732
        Female Urogenital Diseases and Pregnancy Complications 2355
          Female Urogenital Diseases 1915
            female reproductive system disease 1912
              Sexually Transmitted Diseases 221
                Viral Sexually Transmitted Diseases 214
                  human immunodeficiency virus infectious disease 191
                    acquired immunodeficiency syndrome 38
                      AIDS-Related Complex 1
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