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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Body Weight Changes
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Accession:DOID:9003287 term browser browse the term
Definition:A clinical manifestation consisting of alterations in an individual's weight from his or her norm.
Synonyms:exact_synonym: Body Weight Change
 primary_id: MESH:D001836
For additional species annotation, visit the Alliance of Genome Resources.


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Body Weight Changes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lep leptin IMP RGD PMID:21328617 RGD:5128513 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
Cachexia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IEP associated with hepatocellular carcinoma RGD PMID:23200745 RGD:13782066 NCBI chr 1:181,026,606...181,044,859 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 IEP associated with hepatocellular carcinoma RGD PMID:23200745 RGD:13782066 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Bard1 BRCA1 associated RING domain 1 IEP associated with Carcinoma, Hepatocellular;protein:increased expression:skeletal muscle RGD PMID:16685375 RGD:2315732 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G Cd27 CD27 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17878525 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
JBrowse link
G Cdh6 cadherin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17878525 NCBI chr 2:62,079,139...62,225,228
Ensembl chr 2:62,079,137...62,225,228
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta treatment ISO RGD PMID:27122162 RGD:40903021 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Coq7 coenzyme Q7, hydroxylase susceptibility ISO RGD PMID:23166727 RGD:10402105 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158
JBrowse link
G Ddx42 DEAD-box helicase 42 IEP
ISO
associated with Diabetes Mellitus, Experimental;mRNA:increased expression:gastrocnemius muscle (rat)
associated with Malnutrition;mRNA:increased expression:gastrocnemius muscle (mouse)
RGD PMID:14718385 PMID:14718385 RGD:1641826, RGD:1641826 NCBI chr10:91,148,926...91,180,940
Ensembl chr10:91,148,254...91,180,939
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30782979 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:17347304 PMID:12576449 RGD:7242556 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30782979 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1b interleukin 1 beta IDA associated with Inflammation RGD PMID:15005009 RGD:1626680 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist IDA associated with Inflammation RGD PMID:15005009 RGD:1626680 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il6 interleukin 6 IEP
ISO
associated with Leukemia, T-Cell;protein:increased activity:plasma (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:17878525 PMID:9110147 RGD:11062106 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jak2 Janus kinase 2 treatment ISO associated with colon adenocarcinoma RGD PMID:28489606 RGD:127285673 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Lpin1 lipin 1 IEP associated with Carcinoma, Hepatocellular;mRNA:increased expression:skeletal muscle RGD PMID:14718385 RGD:1641826 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lta lymphotoxin alpha susceptibility ISO associated with Breast Neoplasms;DNA:polymorphism:intron:252G>A (human) RGD PMID:18953879 RGD:8548798 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Mc4r melanocortin 4 receptor ISO associated with Myocardial Infarction RGD PMID:20371568 RGD:6484229 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mstn myostatin IEP associated with Carcinoma, Hepatocellular;mRNA:increased expression:skeletal muscle RGD PMID:18578694 RGD:2303552 NCBI chr 9:48,453,982...48,458,809
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Parl presenilin associated, rhomboid-like ISO RGD PMID:16839884 RGD:12902627 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO associated with Pulmonary Disease, Chronic Obstructive (COPD, MeSH:D029424); RNA:decreased expression:skeletal muscle (human) RGD PMID:17459894 RGD:5683621 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17878525 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:17878525 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Slc25a4 solute carrier family 25 member 4 IEP associated with hepatocellular carcinoma RGD PMID:23200745 RGD:13782066 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Tfam transcription factor A, mitochondrial ISO associated with Pulmonary Disease, Chronic Obstructive (COPD, MeSH:D029424); RNA, protein:decreased expression:skeletal muscle (human) RGD PMID:17459894 RGD:5683621 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO RGD PMID:2054795 RGD:7394820 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor ISO
IEP
CTD Direct Evidence: marker/mechanism
associated with hepatocellular carcinoma;mRNA:altered expression:skeletal muscle tissue, adipose tissue (rat)
CTD PMID:17878525 PMID:16077938 RGD:1624190 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP
ISO
associated with Carcinoma, Hepatocellular;protein, mRNA:increased expression:skeletal muscle, adipose tissue
CTD Direct Evidence: therapeutic
CTD PMID:18801959 PMID:16077938 RGD:1624190 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Zfp36 zinc finger protein 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12756304 PMID:15944294 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
Emaciation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgme1 mitochondrial genome maintenance exonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23313956 NCBI chr 3:131,640,770...131,649,933
Ensembl chr 3:131,640,944...131,649,932
JBrowse link
Weight Gain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17194745 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322899 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:12860835 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27020609 PMID:30813227 PMID:31306034 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akap2 A-kinase anchoring protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 5:72,536,986...72,648,524
Ensembl chr 5:72,181,718...72,648,524
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322899 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Anxa2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Anxa5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr14:41,557,918...41,878,622 JBrowse link
G App amyloid beta precursor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arhgef12 Rho guanine nucleotide exchange factor 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Calm1 calmodulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Cav1 caveolin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cavin1 caveolae associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120
JBrowse link
G Cd36 CD36 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Clic4 chloride intracellular channel 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 5:147,456,819...147,513,278
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20107430 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Copg2 COPI coat complex subunit gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618
JBrowse link
G Ctsd cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19997080 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 6:138,839,175...139,155,554
Ensembl chr 6:138,839,177...139,155,536
JBrowse link
G Drd2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20375926 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:30971429 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fam126b family with sequence similarity 126, member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
JBrowse link
G Fbln2 fibulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
JBrowse link
G Fbxo21 F-box protein 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 6:16,654,572...16,694,628
Ensembl chr 6:16,654,614...16,694,626
JBrowse link
G Fgf1 fibroblast growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fggy FGGY carbohydrate kinase domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:29220483 NCBI chr 5:110,398,866...110,786,019
Ensembl chr 5:110,398,863...110,786,017
JBrowse link
G Fstl1 follistatin-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322899 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gh1 growth hormone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17372281 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:16493877 PMID:33301842 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Gnb3 G protein subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16141801 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
JBrowse link
G Gpr55 G protein-coupled receptor 55 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30148676 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
JBrowse link
G Grb14 growth factor receptor bound protein 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
JBrowse link
G Gsn gelsolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Hcrt hypocretin neuropeptide precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27071101 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Hdhd2 haloacid dehalogenase-like hydrolase domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr18:70,475,037...70,526,471
Ensembl chr18:70,474,926...70,526,470
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19434072 PMID:19997080 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27020609 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il7 interleukin 7 ISO CTD Direct Evidence: therapeutic CTD PMID:20376352 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Insig2 insulin induced gene 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18195716 PMID:20373477 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27605626 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27288421 NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798
JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
JBrowse link
G Lbp lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lep leptin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15070752 PMID:15809509 PMID:17502770 PMID:19716478 PMID:21561152 More... NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15809509 PMID:29143802 PMID:29988851 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
JBrowse link
G Map4 microtubule-associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983
JBrowse link
G Mapt microtubule-associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:29203278 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Me1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mest mesoderm specific transcript ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator ISO CTD Direct Evidence: therapeutic CTD PMID:30213948 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
JBrowse link
G Mir21 microRNA 21 ISO CTD Direct Evidence: therapeutic CTD PMID:26996129 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322899 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mprip myosin phosphatase Rho interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr10:44,453,929...44,569,442
Ensembl chr10:44,453,929...44,569,118
JBrowse link
G Myo10 myosin X ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 2:76,100,962...76,304,164
Ensembl chr 2:76,100,987...76,303,030
JBrowse link
G Myo1b myosin Ib ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
JBrowse link
G Ndc1 NDC1 transmembrane nucleoporin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 5:122,155,992...122,202,295
Ensembl chr 5:122,155,967...122,202,291
JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 7:90,481,013...90,487,360 JBrowse link
G Nek7 NIMA-related kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
JBrowse link
G Nid1 nidogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr17:86,085,046...86,158,277
Ensembl chr17:86,085,077...86,158,267
JBrowse link
G Npr3 natriuretic peptide receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G Osbpl8 oxysterol binding protein-like 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:18562099 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr16:28,228,006...28,621,349 JBrowse link
G Pcyox1 prenylcysteine oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 4:118,832,114...118,842,951
Ensembl chr 4:118,830,638...118,842,951
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:4367732 PMID:6143199 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta ISO CTD Direct Evidence: therapeutic CTD PMID:20176998 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Prkd3 protein kinase D3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187
JBrowse link
G Pycard PYD and CARD domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:24508291 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Ramp2 receptor activity modifying protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr10:86,187,366...86,190,692 JBrowse link
G Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr10:106,047,221...106,050,331
Ensembl chr10:106,047,221...106,050,345
JBrowse link
G Rpl28 ribosomal protein L28 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
JBrowse link
G Rps28 ribosomal protein S28 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 7:14,607,801...14,609,170
Ensembl chr 7:14,607,801...14,609,170
JBrowse link
G Rps8 ribosomal protein S8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
JBrowse link
G Ryk receptor-like tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 8:103,419,348...103,492,083
Ensembl chr 8:103,419,275...103,491,698
JBrowse link
G Scd stearoyl-CoA desaturase ISO CTD Direct Evidence: therapeutic CTD PMID:21661758 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
JBrowse link
G Sepsecs Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740
JBrowse link
G Serpinb6a serpin family B member 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr17:30,871,428...30,989,703
Ensembl chr17:30,871,468...31,014,427
JBrowse link
G Sestd1 SEC14 and spectrin domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 3:62,123,590...62,220,759
Ensembl chr 3:62,129,887...62,220,546
JBrowse link
G Setbp1 SET binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr18:72,190,542...72,551,272
Ensembl chr18:72,191,035...72,552,556
JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950
JBrowse link
G Slu7 SLU7 homolog, splicing factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr10:27,908,325...27,923,784
Ensembl chr10:27,908,396...27,923,349
JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Stim2 stromal interaction molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179
JBrowse link
G Sts steroid sulfatase ISO CTD Direct Evidence: therapeutic CTD PMID:24497646 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:21467195 RGD:5147668 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20521320 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tpm4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Tsen2 tRNA splicing endonuclease subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215
JBrowse link
G Vdr vitamin D receptor ISO RGD PMID:30905785 PMID:30905785 RGD:14402029, RGD:14402029 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 5:156,830,509...157,055,895
Ensembl chr 5:156,830,512...157,055,891
JBrowse link
G Zdhhc2 zinc finger DHHC-type palmitoyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060
JBrowse link
G Zwilch zwilch kinetochore protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19030233 NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916
JBrowse link
Weight Loss term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: therapeutic CTD PMID:33007385 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin I converting enzyme 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33007385 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:18230824 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26526685 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Alpk1 alpha-kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157
JBrowse link
G Atg5 autophagy related 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26568842 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26568842 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Cd14 CD14 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28411859 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cln6 CLN6, transmembrane ER protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23789114 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31570772 PMID:32365865 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:27611972 PMID:30102254 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Col2a1 collagen type II alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:26070417 PMID:29908986 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Crh corticotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:8986836 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:8260696 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Fst follistatin ISO CTD Direct Evidence: therapeutic CTD PMID:33034787 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Gh1 growth hormone 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7711889 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:24314293 PMID:27580383 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: therapeutic CTD PMID:24314293 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22940631 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Lep leptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27417254 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lif LIF, interleukin 6 family cytokine ISO CTD Direct Evidence: marker/mechanism CTD PMID:23291613 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31174552 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:24587916 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Mapt microtubule-associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:24556215 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mt1 metallothionein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:24163136 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:25825358 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:18562099 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:1459535 PMID:11193135 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Snca synuclein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:32278788 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24163136 PMID:29434186 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tlr3 toll-like receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28726298 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31442584 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22556341 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link

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  disease 17205
    Pathological Conditions, Signs and Symptoms 10235
      Signs and Symptoms 6497
        Body Weight 943
          Body Weight Changes 235
            Weight Gain 165
            Weight Loss + 68
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