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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Corneal Graft Rejection
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Accession:DOID:9003223 term browser browse the term
Definition:A process in which a transplant recipient's immune system attacks the transplanted cornea. Each layer of the cornea can undergo rejection, endothelial rejection being the most severe form.
Synonyms:exact_synonym: corneal transplant rejection
 primary_id: RDO:9000102



show annotations for term's descendants           Sort by:
Corneal Graft Rejection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule treatment IMP RGD PMID:22300371 RGD:41412184 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd4 Cd4 molecule treatment IMP RGD PMID:1358194 RGD:10059315 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO human gene in a rat model RGD PMID:23723965 RGD:9684950 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    disease of anatomical entity 18212
      immune system disease 4771
        Transplant Rejection 124
          Corneal Graft Rejection 3
Path 2
Term Annotations click to browse term
  disease 21128
    disease of anatomical entity 18212
      nervous system disease 14060
        Neurologic Manifestations 10040
          sensory system disease 6939
            eye disease 3475
              corneal disease 233
                Corneal Graft Rejection 3
paths to the root