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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Invasive Pulmonary Aspergillosis
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Accession:DOID:9003219 term browser browse the term
Definition:Lung infections with the invasive forms of ASPERGILLUS, usually after surgery, transplantation, prolonged NEUTROPENIA or treatment with high-doses of CORTICOSTEROIDS. Invasive pulmonary aspergillosis can progress to CHRONIC NECROTIZING PULMONARY ASPERGILLOSIS or hematogenous spread to other organs.
Synonyms:exact_synonym: Allergic Bronchopulmonary Mycoses;   Allergic Bronchopulmonary Mycosis;   Chronic Necrotizing Pulmonary Aspergillosis;   Pulmonary Aspergilloses, Invasive
 primary_id: MESH:D055744;   RDO:0007719
For additional species annotation, visit the Alliance of Genome Resources.


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Invasive Pulmonary Aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1a interleukin 1 alpha ISO DNA:polymorphism, haplotype:promoter:-889C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chrNW_004936783:1,210,715...1,218,315 JBrowse link
G Il1b interleukin 1 beta ISO DNA:polymorphism, haplotype: :-511C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 ISO protein:increased expression:respiratory system fluid/secretion, serum RGD PMID:24360996 RGD:40903005 NCBI chrNW_004936473:3,573,282...3,589,345 JBrowse link
G Ptx3 pentraxin 3 no_association
susceptibility
ISO protein:increased expression:plasma
DNA:SNP, missense mutation:intron, cds:rs2305619, rs3816527
protein:increased expression:bronchoalveolar lavage fluid, plasma (human)
DNA:SNP:intron:rs1840680 (human)
RGD PMID:29020397 PMID:29964232 RGD:38501098 RGD:38508894 NCBI chrNW_004936519:4,303,549...4,309,143 JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO RGD PMID:23303813 RGD:8655596 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12792
    disease by infectious agent 1642
      Bacterial Infections and Mycoses 628
        fungal infectious disease 78
          Invasive Fungal Infections 8
            Invasive Pulmonary Aspergillosis 5
Path 2
Term Annotations click to browse term
  disease 12792
    disease of anatomical entity 12471
      nervous system disease 10342
        sensory system disease 4707
          skin disease 2409
            Infectious Skin Diseases 167
              dermatomycosis 39
                Hyalohyphomycosis 27
                  aspergillosis 27
                    invasive aspergillosis 19
                      Invasive Pulmonary Aspergillosis 5
paths to the root