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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Invasive Pulmonary Aspergillosis
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Accession:DOID:9003219 term browser browse the term
Definition:Lung infections with the invasive forms of ASPERGILLUS, usually after surgery, transplantation, prolonged NEUTROPENIA or treatment with high-doses of CORTICOSTEROIDS. Invasive pulmonary aspergillosis can progress to CHRONIC NECROTIZING PULMONARY ASPERGILLOSIS or hematogenous spread to other organs.
Synonyms:exact_synonym: Allergic Bronchopulmonary Mycoses;   Allergic Bronchopulmonary Mycosis;   Chronic Necrotizing Pulmonary Aspergillosis;   Pulmonary Aspergilloses, Invasive
 primary_id: MESH:D055744;   RDO:0007719
For additional species annotation, visit the Alliance of Genome Resources.


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Invasive Pulmonary Aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 chemokine (C-C motif) ligand 2 treatment ISO RGD PMID:12917249 RGD:11528529 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CD209 CD209 molecule susceptibility ISO DNA:SNPs:3'utr,intron:multiple RGD PMID:22384201 RGD:39938996 NCBI chr 2:71,394,414...71,397,711
Ensembl chr 2:71,394,390...71,397,969
JBrowse link
G FGF2 fibroblast growth factor 2 treatment ISO RGD PMID:23303813 RGD:8655596 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,878...101,343,916
JBrowse link
G IL1A interleukin 1 alpha ISO DNA:polymorphism, haplotype:promoter:-889C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119
JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 ISO protein:increased expression:respiratory system fluid/secretion, serum RGD PMID:24360996 RGD:40903005 NCBI chr13:34,928,455...34,948,250
Ensembl chr13:34,915,855...34,948,229
JBrowse link
G LOC110258578 interleukin-1 beta-like ISO DNA:polymorphism, haplotype: :-511C>T (human) RGD PMID:18484169 RGD:4142867
G MBL2 mannose binding lectin 2 treatment ISO RGD PMID:17335555 RGD:8693746 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,894...97,108,936
JBrowse link
G PTX3 pentraxin 3 no_association
susceptibility
ISO protein:increased expression:bronchoalveolar lavage fluid, plasma (human)
DNA:SNP, missense mutation:intron, cds:rs2305619, rs3816527
protein:increased expression:plasma
DNA:SNP:intron:rs1840680 (human)
RGD PMID:29020397 PMID:29964232 RGD:38501098 RGD:38508894 NCBI chr13:97,273,594...97,279,570
Ensembl chr13:97,273,594...97,279,569
JBrowse link
G VEGFA vascular endothelial growth factor A treatment ISO RGD PMID:23303813 RGD:8655596 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13437
    disease by infectious agent 1743
      Bacterial Infections and Mycoses 668
        fungal infectious disease 89
          Invasive Fungal Infections 12
            Invasive Pulmonary Aspergillosis 9
Path 2
Term Annotations click to browse term
  disease 13437
    disease of anatomical entity 13099
      nervous system disease 10832
        sensory system disease 4862
          skin disease 2479
            Infectious Skin Diseases 180
              dermatomycosis 48
                Hyalohyphomycosis 36
                  aspergillosis 36
                    invasive aspergillosis 28
                      Invasive Pulmonary Aspergillosis 9
paths to the root