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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Invasive Pulmonary Aspergillosis
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Accession:DOID:9003219 term browser browse the term
Definition:Lung infections with the invasive forms of ASPERGILLUS, usually after surgery, transplantation, prolonged NEUTROPENIA or treatment with high-doses of CORTICOSTEROIDS. Invasive pulmonary aspergillosis can progress to CHRONIC NECROTIZING PULMONARY ASPERGILLOSIS or hematogenous spread to other organs.
Synonyms:exact_synonym: Allergic Bronchopulmonary Mycoses;   Allergic Bronchopulmonary Mycosis;   Chronic Necrotizing Pulmonary Aspergillosis;   Pulmonary Aspergilloses, Invasive
 primary_id: MESH:D055744;   RDO:0007719
For additional species annotation, visit the Alliance of Genome Resources.


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Invasive Pulmonary Aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 chemokine (C-C motif) ligand 2 treatment ISO RGD PMID:12917249 RGD:11528529 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Fgf2 fibroblast growth factor 2 treatment ISO RGD PMID:23303813 RGD:8655596 NCBI chr 3:37,348,477...37,410,106
Ensembl chr 3:37,348,346...37,410,108
JBrowse link
G Il1a interleukin 1 alpha ISO DNA:polymorphism, haplotype:promoter:-889C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta ISO DNA:polymorphism, haplotype: :-511C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Itih4 inter alpha-trypsin inhibitor, heavy chain 4 ISO protein:increased expression:respiratory system fluid/secretion, serum RGD PMID:24360996 RGD:40903005 NCBI chr14:30,886,476...30,901,986
Ensembl chr14:30,886,476...30,902,353
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 treatment ISO RGD PMID:17335555 RGD:8693746 NCBI chr19:30,232,906...30,239,687
Ensembl chr19:30,232,942...30,239,687
JBrowse link
G Ptx3 pentraxin related gene susceptibility
no_association
ISO DNA:SNP:intron:rs1840680 (human)
DNA:SNP, missense mutation:intron, cds:rs2305619, rs3816527
protein:increased expression:plasma
protein:increased expression:bronchoalveolar lavage fluid, plasma (human)
RGD PMID:29020397, PMID:29020397, PMID:29020397, PMID:29964232 RGD:38501098, RGD:38501098, RGD:38501098, RGD:38508894 NCBI chr 3:66,219,887...66,225,806
Ensembl chr 3:66,219,910...66,225,805
JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO RGD PMID:23303813 RGD:8655596 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14272
    disease by infectious agent 1844
      Bacterial Infections and Mycoses 702
        fungal infectious disease 96
          Invasive Fungal Infections 12
            Invasive Pulmonary Aspergillosis 8
Path 2
Term Annotations click to browse term
  disease 14272
    disease of anatomical entity 13872
      nervous system disease 11393
        sensory system disease 5151
          skin disease 2614
            Infectious Skin Diseases 188
              dermatomycosis 51
                Hyalohyphomycosis 39
                  aspergillosis 39
                    invasive aspergillosis 29
                      Invasive Pulmonary Aspergillosis 8
paths to the root