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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Invasive Pulmonary Aspergillosis
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Accession:DOID:9003219 term browser browse the term
Definition:Lung infections with the invasive forms of ASPERGILLUS, usually after surgery, transplantation, prolonged NEUTROPENIA or treatment with high-doses of CORTICOSTEROIDS. Invasive pulmonary aspergillosis can progress to CHRONIC NECROTIZING PULMONARY ASPERGILLOSIS or hematogenous spread to other organs.
Synonyms:exact_synonym: Allergic Bronchopulmonary Mycoses;   Allergic Bronchopulmonary Mycosis;   Chronic Necrotizing Pulmonary Aspergillosis;   Pulmonary Aspergilloses, Invasive
 primary_id: MESH:D055744;   RDO:0007719
For additional species annotation, visit the Alliance of Genome Resources.


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Invasive Pulmonary Aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:12917249 RGD:11528529 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CD209 CD209 molecule susceptibility ISO DNA:SNPs:3'utr,intron:multiple RGD PMID:22384201 RGD:39938996 NCBI chr20:52,517,759...52,542,085
Ensembl chr20:52,518,036...52,520,942
JBrowse link
G FGF2 fibroblast growth factor 2 treatment ISO RGD PMID:23303813 RGD:8655596 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151
JBrowse link
G IL1A interleukin 1 alpha ISO DNA:polymorphism, haplotype:promoter:-889C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435
JBrowse link
G IL1B interleukin 1 beta ISO DNA:polymorphism, haplotype: :-511C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 ISO protein:increased expression:respiratory system fluid/secretion, serum RGD PMID:24360996 RGD:40903005
G LOC479260 mannose-binding protein A treatment ISO RGD PMID:17335555 RGD:8693746 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G PTX3 pentraxin 3 susceptibility
no_association
ISO DNA:SNP:intron:rs1840680 (human)
protein:increased expression:plasma
DNA:SNP, missense mutation:intron, cds:rs2305619, rs3816527
protein:increased expression:bronchoalveolar lavage fluid, plasma (human)
RGD PMID:29020397 PMID:29964232 RGD:38501098 RGD:38508894 NCBI chr23:50,952,835...50,958,607
Ensembl chr23:50,952,885...50,958,167
JBrowse link
G VEGFA vascular endothelial growth factor A treatment ISO RGD PMID:23303813 RGD:8655596 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13595
    disease by infectious agent 1752
      Bacterial Infections and Mycoses 664
        fungal infectious disease 93
          Invasive Fungal Infections 12
            Invasive Pulmonary Aspergillosis 9
Path 2
Term Annotations click to browse term
  disease 13595
    disease of anatomical entity 13255
      nervous system disease 10971
        sensory system disease 4918
          skin disease 2517
            Infectious Skin Diseases 182
              dermatomycosis 48
                Hyalohyphomycosis 36
                  aspergillosis 36
                    invasive aspergillosis 28
                      Invasive Pulmonary Aspergillosis 9
paths to the root