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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Invasive Pulmonary Aspergillosis
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Accession:DOID:9003219 term browser browse the term
Definition:Lung infections with the invasive forms of ASPERGILLUS, usually after surgery, transplantation, prolonged NEUTROPENIA or treatment with high-doses of CORTICOSTEROIDS. Invasive pulmonary aspergillosis can progress to CHRONIC NECROTIZING PULMONARY ASPERGILLOSIS or hematogenous spread to other organs.
Synonyms:exact_synonym: Allergic Bronchopulmonary Mycoses;   Allergic Bronchopulmonary Mycosis;   Chronic Necrotizing Pulmonary Aspergillosis;   Pulmonary Aspergilloses, Invasive
 primary_id: MESH:D055744;   RDO:0007719
For additional species annotation, visit the Alliance of Genome Resources.

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Invasive Pulmonary Aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:12917249 RGD:11528529 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G FGF2 fibroblast growth factor 2 treatment ISO RGD PMID:23303813 RGD:8655596 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G IL1A interleukin 1 alpha ISO DNA:polymorphism, haplotype:promoter:-889C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO DNA:polymorphism, haplotype: :-511C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 ISO protein:increased expression:respiratory system fluid/secretion, serum RGD PMID:24360996 RGD:40903005 NCBI chr 3:52,754,664...52,774,867
Ensembl chr 3:53,980,668...53,998,038
JBrowse link
G MBL2 mannose binding lectin 2 treatment ISO RGD PMID:17335555 RGD:8693746 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
G PTX3 pentraxin 3 no_association
ISO DNA:SNP, missense mutation:intron, cds:rs2305619, rs3816527
protein:increased expression:plasma
DNA:SNP:intron:rs1840680 (human)
protein:increased expression:bronchoalveolar lavage fluid, plasma (human)
RGD PMID:29020397 PMID:29964232 RGD:38501098 RGD:38508894 NCBI chr 3:154,485,470...154,492,293
Ensembl chr 3:162,537,577...162,543,652
JBrowse link
G VEGFA vascular endothelial growth factor A treatment ISO RGD PMID:23303813 RGD:8655596 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13615
    disease by infectious agent 1731
      Bacterial Infections and Mycoses 661
        fungal infectious disease 89
          Invasive Fungal Infections 12
            Invasive Pulmonary Aspergillosis 8
Path 2
Term Annotations click to browse term
  disease 13615
    disease of anatomical entity 13274
      nervous system disease 10972
        sensory system disease 4894
          skin disease 2502
            Infectious Skin Diseases 177
              dermatomycosis 47
                Hyalohyphomycosis 35
                  aspergillosis 35
                    invasive aspergillosis 27
                      Invasive Pulmonary Aspergillosis 8
paths to the root